e-Drug3D

451

HALAZEPAM

DISCONTINUED

INN
HALAZEPAM

cas 23092-17-3

CLASS

NERVOUS SYSTEM
ANXIOLYTIC
BENZODIAZEPINES
MUSCLE RELAXANTS
SEDATIVE
PRECUSOR OF DESMETHYLDIAZEPAM (PMID6123659)

ROUTE (list)

ORAL

ATC code

N05BA13

PK parameters

Cl 24 LITER / HOUR (PMID1980307)
t1/2 21.15 HOUR

Target

TARGET GAMMA-AMINOBUTYRIC-ACID RECEPTOR

GABA-A receptor

Download SDF file

7-chloro-5-phenyl-1-(2,2,2-trifluoroethyl)-3H-1,4-benzodiazepin-2-one

Formula:
C17H12ClF3N2O

Calculated chemical properties:

MW 352.74
NB_atoms 24
XLogP 4.09
PSA 27.719
NB_HD 0
NB_HA 3
fsp3 0.18
Lipinski(0=no;1=yes) 1

FDA
NDA 017736 (pdf not found) INN (HALAZEPAM) PAXIPAM (SCHERING) APPROVAL= AP YEAR= 1981 NEWMOLECULARENTITY DISCONTINUED