e-Drug3D

443

LOMUSTINE

INN
LOMUSTINE

cas 13010-47-4

CLASS

ANTINEOPLASTIC
ALKYLATING
NITROSOUREAS

ROUTE (list)

ORAL

ATC code

L01AD02

PK parameters

Solubility

RELATIVELY INSOLUBLE IN WATER (< 0.05 MILLIGRAM PER MILLILITER)

Target

TARGET DNA
RNA

Unknown

Download SDF file

1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea

Formula:
C9H16ClN3O2

Calculated chemical properties:

MW 233.70
NB_atoms 15
XLogP 2.25
PSA 60.087
NB_HD 1
NB_HA 5
fsp3 0.89
Lipinski(0=no;1=yes) 1

FDA
NDA 017588 (pdf not found) INN (LOMUSTINE) GLEOSTINE (AZURITY) APPROVAL= AP YEAR= 1976