e-Drug3D
442
NAPROXEN
INN
NAPROXEN
cas 22204-53-1
CLASS
MUSCULO-SKELETAL
CYCLOOXYGENASE INHIBITORS
ANTIPYRETIC
ANTIINFLAMMATORY
ANALGESIC
NSAID
ROUTE (list)
ORAL
PK parameters
F 95 PERCENT
Tmax 3 HOUR
VD 10.4 LITER (65 KILOGRAM)
Cl 0.507 LITER / HOUR (65 KILOGRAM)
PPB 99 PERCENT
t1/2 14.5 HOUR
Solubility
FREELY SOLUBLE IN WATER AT NEUTRAL PH (LOGP = 1.6)
TARGET PROSTAGLANDIN G/H SYNTHASE 1
PROSTAGLANDIN G/H SYNTHASE 2
PROSTAGLANDIN G/H SYNTHASE 2
PDB
4OR0 (CRYSTAL STRUCTURE OF BOVINE SERUM ALBUMIN IN COMPLEX WITH NAPROXEN)
Ligand code = NPS (link to the list of PDB complexes)
Download experimental 3D coordinates of NPS with added hydrogens
Prostaglandin G,H synthase 2 UNIPROT P35354 PTGS2
Prostaglandin G,H synthase 1 UNIPROT P23219 PTGS1
Formula:
C14H14O3
Calculated chemical properties:
MW 229.24
NB_atoms 17
XLogP 1.70
PSA 45.475
NB_HD 0
NB_HA 3
fsp3 0.21
Lipinski(0=no;1=yes) 1
NB_atoms 17
XLogP 1.70
PSA 45.475
NB_HD 0
NB_HA 3
fsp3 0.21
Lipinski(0=no;1=yes) 1
FDA
NDA 074319 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (PUREPAC PHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 017581 (pdf not found) INN (NAPROXEN) NAPROSYN (ATNAHS PHARMA US) APPROVAL= AP YEAR= 1976
NDA 018164 (pdf not found) INN (NAPROXEN SODIUM) ANAPROX (ATNAHS PHARMA US) APPROVAL= AP YEAR= 1980
NDA 018965 (pdf not found) INN (NAPROXEN) NAPROSYN (ATNAHS PHARMA US) APPROVAL= AP YEAR= 1987
NDA 074110 (pdf not found) INN (NAPROXEN) NAPROXEN (HAMILTON PHARMS) APPROVAL= AP YEAR= 1992 DISCONTINUED
NDA 074105 (pdf not found) INN (NAPROXEN) NAPROXEN (DAVA PHARMS INC) APPROVAL= AP YEAR= 1993 DISCONTINUED
NDA 074106 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (HAMILTON PHARMS) APPROVAL= AP YEAR= 1993 DISCONTINUED
NDA 074121 (pdf not found) INN (NAPROXEN) NAPROXEN (PHARMOBEDIENT) APPROVAL= AP YEAR= 1993 DISCONTINUED
NDA 074129 (pdf not found) INN (NAPROXEN) NAPROXEN (TEVA) APPROVAL= AP YEAR= 1993 DISCONTINUED
NDA 074140 (pdf not found) INN (NAPROXEN) NAPROXEN (GRANULES) APPROVAL= AP YEAR= 1993
NDA 074142 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (TEVA) APPROVAL= AP YEAR= 1993 DISCONTINUED
NDA 074162 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (SANDOZ) APPROVAL= AP YEAR= 1993 DISCONTINUED
NDA 074195 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (WATSON LABS) APPROVAL= AP YEAR= 1993 DISCONTINUED
NDA 074198 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (TEVA) APPROVAL= AP YEAR= 1993 DISCONTINUED
NDA 074201 (pdf not found) INN (NAPROXEN) NAPROXEN (TEVA) APPROVAL= AP YEAR= 1993
NDA 074207 (pdf not found) INN (NAPROXEN) NAPROXEN (TEVA PHARMS) APPROVAL= AP YEAR= 1993 DISCONTINUED
NDA 074257 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (ROXANE) APPROVAL= AP YEAR= 1993 DISCONTINUED
NDA 074263 (pdf not found) INN (NAPROXEN) NAPROXEN (PUREPAC PHARM) APPROVAL= TA YEAR= 1993
NDA 020067 (pdf not found) INN (NAPROXEN) EC-NAPROSYN (ATNAHS PHARMA US) APPROVAL= AP YEAR= 1994
NDA 020204 (pdf not found) INN (NAPROXEN SODIUM) ALEVE (BAYER) APPROVAL= AP YEAR= 1994
NDA 074190 (pdf not found) INN (NAPROXEN) NAPROXEN (HIKMA) APPROVAL= AP YEAR= 1994
NDA 074211 (pdf not found) INN (NAPROXEN) NAPROXEN (ROXANE) APPROVAL= AP YEAR= 1994 DISCONTINUED
NDA 074289 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (TEVA PHARMS) APPROVAL= AP YEAR= 1994 DISCONTINUED
NDA 074367 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (PHARMOBEDIENT) APPROVAL= AP YEAR= 1994 DISCONTINUED
NDA 074495 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (SANDOZ) APPROVAL= AP YEAR= 1994 DISCONTINUED
NDA 074111 (pdf not found) INN (NAPROXEN) NAPROXEN (IVAX SUB TEVA PHARMS) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 074163 (pdf not found) INN (NAPROXEN) NAPROXEN (WATSON LABS TEVA) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 074230 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (IVAX SUB TEVA PHARMS) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 074410 (pdf not found) INN (NAPROXEN) NAPROXEN (CHARTWELL MOLECULES) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 074455 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (WATSON LABS) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 074457 (pdf not found) INN (NAPROXEN) NAPROXEN (WATSON LABS) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 020353 (pdf not found) INN (NAPROXEN SODIUM) NAPRELAN (TWI PHARMS) APPROVAL= AP YEAR= 1996
NDA 074182 (pdf not found) INN (NAPROXEN) NAPROXEN (PLIVA) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 074216 (pdf not found) INN (NAPROXEN) NAPROXEN (TEVA) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 074242 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (PLIVA) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 074480 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (HIKMA) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 074635 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (CONTRACT PHARMACAL) APPROVAL= AP YEAR= 1997
NDA 074646 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (PLD ACQUISITIONS LLC) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 074661 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (PERRIGO) APPROVAL= AP YEAR= 1997
NDA 074789 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (CONTRACT PHARMACAL) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 074936 (pdf not found) INN (NAPROXEN) NAPROXEN (ACTAVIS ELIZABETH) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 075061 (pdf not found) INN (NAPROXEN) NAPROXEN (FOSUN PHARMA) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 075168 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (DR REDDYS LABS INC) APPROVAL= AP YEAR= 1998
NDA 075227 (pdf not found) INN (NAPROXEN) NAPROXEN (TEVA) APPROVAL= AP YEAR= 1998
NDA 021076 (pdf not found) INN (NAPROXEN SODIUM ; PSEUDOEPHEDRINE HYDROCHLORIDE) ALEVE-D SINUS & COLD (BAYER) APPROVAL= AP YEAR= 1999 DISCONTINUED
NDA 075337 (pdf not found) INN (NAPROXEN) NAPROXEN (PLIVA) APPROVAL= AP YEAR= 1999 DISCONTINUED
NDA 075390 (pdf not found) INN (NAPROXEN) NAPROXEN (AUROBINDO PHARMA USA) APPROVAL= AP YEAR= 2001
NDA 075927 (pdf not found) INN (NAPROXEN) NAPROXEN (AMNEAL PHARMS NY) APPROVAL= AP YEAR= 2001
NDA 075416 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (ACTAVIS LABS FL INC) APPROVAL= AP YEAR= 2002
NDA 021507 (pdf not found) INN (LANSOPRAZOLE ; NAPROXEN) PREVACID NAPRAPAC 250 COPACKAGED (TAKEDA PHARMS NA) APPROVAL= AP YEAR= 2003 DISCONTINUED
NDA 076544 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (ABLE) APPROVAL= AP YEAR= 2003 DISCONTINUED
NDA 076494 (pdf not found) INN (NAPROXEN) NAPROXEN (HIKMA INTL PHARMS) APPROVAL= AP YEAR= 2004 DISCONTINUED
NDA 076518 (pdf not found) INN (NAPROXEN SODIUM ; PSEUDOEPHEDRINE HYDROCHLORIDE) NAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDE (PERRIGO) APPROVAL= AP YEAR= 2004
NDA 077339 (pdf not found) INN (NAPROXEN) NAPROXEN (L PERRIGO CO) APPROVAL= AP YEAR= 2005 DISCONTINUED
NDA 021920 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (BIONPHARMA) APPROVAL= AP YEAR= 2006
NDA 077381 (pdf not found) INN (NAPROXEN SODIUM ; PSEUDOEPHEDRINE HYDROCHLORIDE) NAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDE (DR REDDYS LABS INC) APPROVAL= AP YEAR= 2006
NDA 078250 (pdf not found) INN (NAPROXEN) NAPROXEN (GLENMARK PHARMS LTD) APPROVAL= AP YEAR= 2007
NDA 078314 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (GLENMARK PHARMS LTD) APPROVAL= AP YEAR= 2007
NDA 078432 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (AMNEAL PHARMS NY) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 078486 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (DR REDDYS LABS LTD) APPROVAL= AP YEAR= 2007
NDA 078620 (pdf not found) INN (NAPROXEN) NAPROXEN (ZYDUS PHARMS USA) APPROVAL= AP YEAR= 2007
NDA 021926 (pdf not found) INN (NAPROXEN SODIUM ; SUMATRIPTAN SUCCINATE) TREXIMET (CURRAX) APPROVAL= AP YEAR= 2008
NDA 079096 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (AMNEAL PHARMS NY) APPROVAL= AP YEAR= 2008
NDA 022511 (pdf not found) INN (ESOMEPRAZOLE MAGNESIUM ; NAPROXEN) VIMOVO (HORIZON) APPROVAL= AP YEAR= 2010 DISCONTINUED
NDA 090545 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (MARKSANS PHARMA) APPROVAL= AP YEAR= 2011
NDA 090930 (pdf not found) INN (SUMATRIPTAN ; NAPROXEN SODIUM) SUMATRIPTAN; NAPROXEN SODIUM (DR REDDYS LABS LTD) APPROVAL= TA YEAR= 2011
NDA 091183 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (SUN PHARM INDS LTD) APPROVAL= AP YEAR= 2011 DISCONTINUED
NDA 091416 (pdf not found) INN (NAPROXEN) NAPROXEN (ADAPTIS) APPROVAL= AP YEAR= 2011
NDA 091305 (pdf not found) INN (NAPROXEN) NAPROXEN (INVAGEN PHARMS) APPROVAL= AP YEAR= 2011 DISCONTINUED
NDA 091353 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (GRANULES INDIA) APPROVAL= AP YEAR= 2011
NDA 091432 (pdf not found) INN (NAPROXEN) NAPROXEN (NUVO PHARMS INC) APPROVAL= AP YEAR= 2011
NDA 200429 (pdf not found) INN (NAPROXEN) NAPROXEN (AUROBINDO PHARMA) APPROVAL= AP YEAR= 2011
NDA 200629 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (AUROBINDO PHARMA LTD) APPROVAL= AP YEAR= 2011
NDA 090753 (pdf not found) INN (SUMATRIPTAN ; NAPROXEN SODIUM) SUMATRIPTAN; NAPROXEN SODIUM (PAR PHARM) APPROVAL= TA YEAR= 2013
NDA 205352 (pdf not found) INN (DIPHENHYDRAMINE HYDROCHLORIDE ; NAPROXEN SODIUM) ALEVE PM (BAYER HLTHCARE) APPROVAL= AP YEAR= 2014
NDA 205497 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (AUROBINDO PHARMA LTD) APPROVAL= AP YEAR= 2016
NDA 204872 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (LNK INTL INC) APPROVAL= AP YEAR= 2017
NDA 090872 (pdf not found) INN (NAPROXEN SODIUM ; SUMATRIPTAN SUCCINATE) SUMATRIPTAN AND NAPROXEN SODIUM (RISING) APPROVAL= AP YEAR= 2018
NDA 202461 (pdf not found) INN (ESOMEPRAZOLE MAGNESIUM ; NAPROXEN) NAPROXEN AND ESOMEPRAZOLE MAGNESIUM (DR REDDYS LABS LTD) APPROVAL= TA YEAR= 2018
NDA 207457 (pdf not found) INN (NAPROXEN SODIUM ; SUMATRIPTAN SUCCINATE) SUMATRIPTAN AND NAPROXEN SODIUM (AUROBINDO PHARMA LTD) APPROVAL= AP YEAR= 2018
NDA 202803 (pdf not found) INN (NAPROXEN SODIUM ; SUMATRIPTAN SUCCINATE) SUMATRIPTAN AND NAPROXEN SODIUM (SUN PHARM) APPROVAL= AP YEAR= 2018
NDA 207612 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (NOVELGENIX THERAPS) APPROVAL= AP YEAR= 2018 DISCONTINUED
NDA 208363 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (PURACAP PHARM LLC) APPROVAL= AP YEAR= 2018
NDA 209726 (pdf not found) INN (DIPHENHYDRAMINE HYDROCHLORIDE ; NAPROXEN SODIUM) NAPROXEN SODIUM AND DIPHENHYDRAMINE HYDROCHLORIDE (AMNEAL PHARMS CO) APPROVAL= AP YEAR= 2018
NDA 202807 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (CATALENT) APPROVAL= AP YEAR= 2019
NDA 207597 (pdf not found) INN (DIPHENHYDRAMINE HYDROCHLORIDE ; NAPROXEN SODIUM) NAPROXEN SODIUM AND DIPHENHYDRAMINE HYDROCHLORIDE (P AND L) APPROVAL= AP YEAR= 2019 DISCONTINUED
NDA 208499 (pdf not found) INN (DIPHENHYDRAMINE HYDROCHLORIDE ; NAPROXEN SODIUM) NAPROXEN SODIUM AND DIPHENHYDRAMINE HYDROCHLORIDE (PERRIGO R AND D) APPROVAL= AP YEAR= 2019
NDA 211830 (pdf not found) INN (DIPHENHYDRAMINE HYDROCHLORIDE ; NAPROXEN SODIUM) NAPROXEN SODIUM AND DIPHENHYDRAMINE HYDROCHLORIDE (COREPHARMA) APPROVAL= AP YEAR= 2019
NDA 212033 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (YICHANG HUMANWELL) APPROVAL= AP YEAR= 2019
NDA 212199 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (SCIEGEN PHARMS INC) APPROVAL= AP YEAR= 2019
NDA 204206 (pdf not found) INN (ESOMEPRAZOLE MAGNESIUM ; NAPROXEN) NAPROXEN AND ESOMEPRAZOLE MAGNESIUM (DR REDDYS) APPROVAL= AP YEAR= 2020
NDA 212517 (pdf not found) INN (NAPROXEN) NAPROXEN (SCIEGEN PHARMS INC) APPROVAL= AP YEAR= 2020
NDA 212705 (pdf not found) INN (NAPROXEN) NAPROXEN (AMNEAL) APPROVAL= AP YEAR= 2020
NDA 213663 (pdf not found) INN (DIPHENHYDRAMINE HYDROCHLORIDE ; NAPROXEN SODIUM) NAPROXEN SODIUM AND DIPHENHYDRAMINE HYDROCHLORIDE (GRANULES) APPROVAL= AP YEAR= 2020
NDA 211910 (pdf not found) INN (NAPROXEN) NAPROXEN (NOVITIUM PHARMA) APPROVAL= AP YEAR= 2021
NDA 204920 (pdf not found) INN (ESOMEPRAZOLE MAGNESIUM ; NAPROXEN) NAPROXEN AND ESOMEPRAZOLE MAGNESIUM (PHARMOBEDIENT) APPROVAL= AP YEAR= 2021 DISCONTINUED
NDA 211360 (pdf not found) INN (NAPROXEN SODIUM ; PSEUDOEPHEDRINE HYDROCHLORIDE) NAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDE (AUROBINDO PHARMA) APPROVAL= AP YEAR= 2022 DISCONTINUED
NDA 215776 (pdf not found) INN (NAPROXEN) NAPROXEN (HETERO LABS LTD III) APPROVAL= AP YEAR= 2022
NDA 204470 (pdf not found) INN (ESOMEPRAZOLE MAGNESIUM ; NAPROXEN) NAPROXEN AND ESOMEPRAZOLE MAGNESIUM (ACTAVIS LABS FL INC) APPROVAL= AP YEAR= 2022 DISCONTINUED
NDA 211065 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (HETERO LABS LTD V) APPROVAL= AP YEAR= 2022
NDA 213699 (pdf not found) INN (ESOMEPRAZOLE MAGNESIUM ; NAPROXEN) NAPROXEN AND ESOMEPRAZOLE MAGNESIUM (AJANTA PHARMA LTD) APPROVAL= AP YEAR= 2022
NDA 215472 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (ONESOURCE SPECIALTY) APPROVAL= AP YEAR= 2022 DISCONTINUED
NDA 214463 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (PATHEON SOFTGELS) APPROVAL= AP YEAR= 2023
NDA 216908 (pdf not found) INN (NAPROXEN) NAPROXEN (TRUPHARMA) APPROVAL= AP YEAR= 2023
NDA 217738 (pdf not found) INN (ESOMEPRAZOLE MAGNESIUM ; NAPROXEN) NAPROXEN AND ESOMEPRAZOLE MAGNESIUM (SCIEGEN PHARMS INC) APPROVAL= AP YEAR= 2023
NDA 218497 (pdf not found) INN (NAPROXEN) NAPROXEN (NOVITIUM PHARMA) APPROVAL= AP YEAR= 2024
NDA 074319 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (PUREPAC PHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 017581 (pdf not found) INN (NAPROXEN) NAPROSYN (ATNAHS PHARMA US) APPROVAL= AP YEAR= 1976
NDA 018164 (pdf not found) INN (NAPROXEN SODIUM) ANAPROX (ATNAHS PHARMA US) APPROVAL= AP YEAR= 1980
NDA 018965 (pdf not found) INN (NAPROXEN) NAPROSYN (ATNAHS PHARMA US) APPROVAL= AP YEAR= 1987
NDA 074110 (pdf not found) INN (NAPROXEN) NAPROXEN (HAMILTON PHARMS) APPROVAL= AP YEAR= 1992 DISCONTINUED
NDA 074105 (pdf not found) INN (NAPROXEN) NAPROXEN (DAVA PHARMS INC) APPROVAL= AP YEAR= 1993 DISCONTINUED
NDA 074106 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (HAMILTON PHARMS) APPROVAL= AP YEAR= 1993 DISCONTINUED
NDA 074121 (pdf not found) INN (NAPROXEN) NAPROXEN (PHARMOBEDIENT) APPROVAL= AP YEAR= 1993 DISCONTINUED
NDA 074129 (pdf not found) INN (NAPROXEN) NAPROXEN (TEVA) APPROVAL= AP YEAR= 1993 DISCONTINUED
NDA 074140 (pdf not found) INN (NAPROXEN) NAPROXEN (GRANULES) APPROVAL= AP YEAR= 1993
NDA 074142 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (TEVA) APPROVAL= AP YEAR= 1993 DISCONTINUED
NDA 074162 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (SANDOZ) APPROVAL= AP YEAR= 1993 DISCONTINUED
NDA 074195 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (WATSON LABS) APPROVAL= AP YEAR= 1993 DISCONTINUED
NDA 074198 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (TEVA) APPROVAL= AP YEAR= 1993 DISCONTINUED
NDA 074201 (pdf not found) INN (NAPROXEN) NAPROXEN (TEVA) APPROVAL= AP YEAR= 1993
NDA 074207 (pdf not found) INN (NAPROXEN) NAPROXEN (TEVA PHARMS) APPROVAL= AP YEAR= 1993 DISCONTINUED
NDA 074257 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (ROXANE) APPROVAL= AP YEAR= 1993 DISCONTINUED
NDA 074263 (pdf not found) INN (NAPROXEN) NAPROXEN (PUREPAC PHARM) APPROVAL= TA YEAR= 1993
NDA 020067 (pdf not found) INN (NAPROXEN) EC-NAPROSYN (ATNAHS PHARMA US) APPROVAL= AP YEAR= 1994
NDA 020204 (pdf not found) INN (NAPROXEN SODIUM) ALEVE (BAYER) APPROVAL= AP YEAR= 1994
NDA 074190 (pdf not found) INN (NAPROXEN) NAPROXEN (HIKMA) APPROVAL= AP YEAR= 1994
NDA 074211 (pdf not found) INN (NAPROXEN) NAPROXEN (ROXANE) APPROVAL= AP YEAR= 1994 DISCONTINUED
NDA 074289 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (TEVA PHARMS) APPROVAL= AP YEAR= 1994 DISCONTINUED
NDA 074367 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (PHARMOBEDIENT) APPROVAL= AP YEAR= 1994 DISCONTINUED
NDA 074495 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (SANDOZ) APPROVAL= AP YEAR= 1994 DISCONTINUED
NDA 074111 (pdf not found) INN (NAPROXEN) NAPROXEN (IVAX SUB TEVA PHARMS) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 074163 (pdf not found) INN (NAPROXEN) NAPROXEN (WATSON LABS TEVA) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 074230 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (IVAX SUB TEVA PHARMS) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 074410 (pdf not found) INN (NAPROXEN) NAPROXEN (CHARTWELL MOLECULES) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 074455 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (WATSON LABS) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 074457 (pdf not found) INN (NAPROXEN) NAPROXEN (WATSON LABS) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 020353 (pdf not found) INN (NAPROXEN SODIUM) NAPRELAN (TWI PHARMS) APPROVAL= AP YEAR= 1996
NDA 074182 (pdf not found) INN (NAPROXEN) NAPROXEN (PLIVA) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 074216 (pdf not found) INN (NAPROXEN) NAPROXEN (TEVA) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 074242 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (PLIVA) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 074480 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (HIKMA) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 074635 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (CONTRACT PHARMACAL) APPROVAL= AP YEAR= 1997
NDA 074646 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (PLD ACQUISITIONS LLC) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 074661 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (PERRIGO) APPROVAL= AP YEAR= 1997
NDA 074789 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (CONTRACT PHARMACAL) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 074936 (pdf not found) INN (NAPROXEN) NAPROXEN (ACTAVIS ELIZABETH) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 075061 (pdf not found) INN (NAPROXEN) NAPROXEN (FOSUN PHARMA) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 075168 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (DR REDDYS LABS INC) APPROVAL= AP YEAR= 1998
NDA 075227 (pdf not found) INN (NAPROXEN) NAPROXEN (TEVA) APPROVAL= AP YEAR= 1998
NDA 021076 (pdf not found) INN (NAPROXEN SODIUM ; PSEUDOEPHEDRINE HYDROCHLORIDE) ALEVE-D SINUS & COLD (BAYER) APPROVAL= AP YEAR= 1999 DISCONTINUED
NDA 075337 (pdf not found) INN (NAPROXEN) NAPROXEN (PLIVA) APPROVAL= AP YEAR= 1999 DISCONTINUED
NDA 075390 (pdf not found) INN (NAPROXEN) NAPROXEN (AUROBINDO PHARMA USA) APPROVAL= AP YEAR= 2001
NDA 075927 (pdf not found) INN (NAPROXEN) NAPROXEN (AMNEAL PHARMS NY) APPROVAL= AP YEAR= 2001
NDA 075416 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (ACTAVIS LABS FL INC) APPROVAL= AP YEAR= 2002
NDA 021507 (pdf not found) INN (LANSOPRAZOLE ; NAPROXEN) PREVACID NAPRAPAC 250 COPACKAGED (TAKEDA PHARMS NA) APPROVAL= AP YEAR= 2003 DISCONTINUED
NDA 076544 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (ABLE) APPROVAL= AP YEAR= 2003 DISCONTINUED
NDA 076494 (pdf not found) INN (NAPROXEN) NAPROXEN (HIKMA INTL PHARMS) APPROVAL= AP YEAR= 2004 DISCONTINUED
NDA 076518 (pdf not found) INN (NAPROXEN SODIUM ; PSEUDOEPHEDRINE HYDROCHLORIDE) NAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDE (PERRIGO) APPROVAL= AP YEAR= 2004
NDA 077339 (pdf not found) INN (NAPROXEN) NAPROXEN (L PERRIGO CO) APPROVAL= AP YEAR= 2005 DISCONTINUED
NDA 021920 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (BIONPHARMA) APPROVAL= AP YEAR= 2006
NDA 077381 (pdf not found) INN (NAPROXEN SODIUM ; PSEUDOEPHEDRINE HYDROCHLORIDE) NAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDE (DR REDDYS LABS INC) APPROVAL= AP YEAR= 2006
NDA 078250 (pdf not found) INN (NAPROXEN) NAPROXEN (GLENMARK PHARMS LTD) APPROVAL= AP YEAR= 2007
NDA 078314 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (GLENMARK PHARMS LTD) APPROVAL= AP YEAR= 2007
NDA 078432 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (AMNEAL PHARMS NY) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 078486 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (DR REDDYS LABS LTD) APPROVAL= AP YEAR= 2007
NDA 078620 (pdf not found) INN (NAPROXEN) NAPROXEN (ZYDUS PHARMS USA) APPROVAL= AP YEAR= 2007
NDA 021926 (pdf not found) INN (NAPROXEN SODIUM ; SUMATRIPTAN SUCCINATE) TREXIMET (CURRAX) APPROVAL= AP YEAR= 2008
NDA 079096 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (AMNEAL PHARMS NY) APPROVAL= AP YEAR= 2008
NDA 022511 (pdf not found) INN (ESOMEPRAZOLE MAGNESIUM ; NAPROXEN) VIMOVO (HORIZON) APPROVAL= AP YEAR= 2010 DISCONTINUED
NDA 090545 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (MARKSANS PHARMA) APPROVAL= AP YEAR= 2011
NDA 090930 (pdf not found) INN (SUMATRIPTAN ; NAPROXEN SODIUM) SUMATRIPTAN; NAPROXEN SODIUM (DR REDDYS LABS LTD) APPROVAL= TA YEAR= 2011
NDA 091183 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (SUN PHARM INDS LTD) APPROVAL= AP YEAR= 2011 DISCONTINUED
NDA 091416 (pdf not found) INN (NAPROXEN) NAPROXEN (ADAPTIS) APPROVAL= AP YEAR= 2011
NDA 091305 (pdf not found) INN (NAPROXEN) NAPROXEN (INVAGEN PHARMS) APPROVAL= AP YEAR= 2011 DISCONTINUED
NDA 091353 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (GRANULES INDIA) APPROVAL= AP YEAR= 2011
NDA 091432 (pdf not found) INN (NAPROXEN) NAPROXEN (NUVO PHARMS INC) APPROVAL= AP YEAR= 2011
NDA 200429 (pdf not found) INN (NAPROXEN) NAPROXEN (AUROBINDO PHARMA) APPROVAL= AP YEAR= 2011
NDA 200629 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (AUROBINDO PHARMA LTD) APPROVAL= AP YEAR= 2011
NDA 090753 (pdf not found) INN (SUMATRIPTAN ; NAPROXEN SODIUM) SUMATRIPTAN; NAPROXEN SODIUM (PAR PHARM) APPROVAL= TA YEAR= 2013
NDA 205352 (pdf not found) INN (DIPHENHYDRAMINE HYDROCHLORIDE ; NAPROXEN SODIUM) ALEVE PM (BAYER HLTHCARE) APPROVAL= AP YEAR= 2014
NDA 205497 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (AUROBINDO PHARMA LTD) APPROVAL= AP YEAR= 2016
NDA 204872 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (LNK INTL INC) APPROVAL= AP YEAR= 2017
NDA 090872 (pdf not found) INN (NAPROXEN SODIUM ; SUMATRIPTAN SUCCINATE) SUMATRIPTAN AND NAPROXEN SODIUM (RISING) APPROVAL= AP YEAR= 2018
NDA 202461 (pdf not found) INN (ESOMEPRAZOLE MAGNESIUM ; NAPROXEN) NAPROXEN AND ESOMEPRAZOLE MAGNESIUM (DR REDDYS LABS LTD) APPROVAL= TA YEAR= 2018
NDA 207457 (pdf not found) INN (NAPROXEN SODIUM ; SUMATRIPTAN SUCCINATE) SUMATRIPTAN AND NAPROXEN SODIUM (AUROBINDO PHARMA LTD) APPROVAL= AP YEAR= 2018
NDA 202803 (pdf not found) INN (NAPROXEN SODIUM ; SUMATRIPTAN SUCCINATE) SUMATRIPTAN AND NAPROXEN SODIUM (SUN PHARM) APPROVAL= AP YEAR= 2018
NDA 207612 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (NOVELGENIX THERAPS) APPROVAL= AP YEAR= 2018 DISCONTINUED
NDA 208363 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (PURACAP PHARM LLC) APPROVAL= AP YEAR= 2018
NDA 209726 (pdf not found) INN (DIPHENHYDRAMINE HYDROCHLORIDE ; NAPROXEN SODIUM) NAPROXEN SODIUM AND DIPHENHYDRAMINE HYDROCHLORIDE (AMNEAL PHARMS CO) APPROVAL= AP YEAR= 2018
NDA 202807 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (CATALENT) APPROVAL= AP YEAR= 2019
NDA 207597 (pdf not found) INN (DIPHENHYDRAMINE HYDROCHLORIDE ; NAPROXEN SODIUM) NAPROXEN SODIUM AND DIPHENHYDRAMINE HYDROCHLORIDE (P AND L) APPROVAL= AP YEAR= 2019 DISCONTINUED
NDA 208499 (pdf not found) INN (DIPHENHYDRAMINE HYDROCHLORIDE ; NAPROXEN SODIUM) NAPROXEN SODIUM AND DIPHENHYDRAMINE HYDROCHLORIDE (PERRIGO R AND D) APPROVAL= AP YEAR= 2019
NDA 211830 (pdf not found) INN (DIPHENHYDRAMINE HYDROCHLORIDE ; NAPROXEN SODIUM) NAPROXEN SODIUM AND DIPHENHYDRAMINE HYDROCHLORIDE (COREPHARMA) APPROVAL= AP YEAR= 2019
NDA 212033 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (YICHANG HUMANWELL) APPROVAL= AP YEAR= 2019
NDA 212199 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (SCIEGEN PHARMS INC) APPROVAL= AP YEAR= 2019
NDA 204206 (pdf not found) INN (ESOMEPRAZOLE MAGNESIUM ; NAPROXEN) NAPROXEN AND ESOMEPRAZOLE MAGNESIUM (DR REDDYS) APPROVAL= AP YEAR= 2020
NDA 212517 (pdf not found) INN (NAPROXEN) NAPROXEN (SCIEGEN PHARMS INC) APPROVAL= AP YEAR= 2020
NDA 212705 (pdf not found) INN (NAPROXEN) NAPROXEN (AMNEAL) APPROVAL= AP YEAR= 2020
NDA 213663 (pdf not found) INN (DIPHENHYDRAMINE HYDROCHLORIDE ; NAPROXEN SODIUM) NAPROXEN SODIUM AND DIPHENHYDRAMINE HYDROCHLORIDE (GRANULES) APPROVAL= AP YEAR= 2020
NDA 211910 (pdf not found) INN (NAPROXEN) NAPROXEN (NOVITIUM PHARMA) APPROVAL= AP YEAR= 2021
NDA 204920 (pdf not found) INN (ESOMEPRAZOLE MAGNESIUM ; NAPROXEN) NAPROXEN AND ESOMEPRAZOLE MAGNESIUM (PHARMOBEDIENT) APPROVAL= AP YEAR= 2021 DISCONTINUED
NDA 211360 (pdf not found) INN (NAPROXEN SODIUM ; PSEUDOEPHEDRINE HYDROCHLORIDE) NAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDE (AUROBINDO PHARMA) APPROVAL= AP YEAR= 2022 DISCONTINUED
NDA 215776 (pdf not found) INN (NAPROXEN) NAPROXEN (HETERO LABS LTD III) APPROVAL= AP YEAR= 2022
NDA 204470 (pdf not found) INN (ESOMEPRAZOLE MAGNESIUM ; NAPROXEN) NAPROXEN AND ESOMEPRAZOLE MAGNESIUM (ACTAVIS LABS FL INC) APPROVAL= AP YEAR= 2022 DISCONTINUED
NDA 211065 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (HETERO LABS LTD V) APPROVAL= AP YEAR= 2022
NDA 213699 (pdf not found) INN (ESOMEPRAZOLE MAGNESIUM ; NAPROXEN) NAPROXEN AND ESOMEPRAZOLE MAGNESIUM (AJANTA PHARMA LTD) APPROVAL= AP YEAR= 2022
NDA 215472 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (ONESOURCE SPECIALTY) APPROVAL= AP YEAR= 2022 DISCONTINUED
NDA 214463 (pdf not found) INN (NAPROXEN SODIUM) NAPROXEN SODIUM (PATHEON SOFTGELS) APPROVAL= AP YEAR= 2023
NDA 216908 (pdf not found) INN (NAPROXEN) NAPROXEN (TRUPHARMA) APPROVAL= AP YEAR= 2023
NDA 217738 (pdf not found) INN (ESOMEPRAZOLE MAGNESIUM ; NAPROXEN) NAPROXEN AND ESOMEPRAZOLE MAGNESIUM (SCIEGEN PHARMS INC) APPROVAL= AP YEAR= 2023
NDA 218497 (pdf not found) INN (NAPROXEN) NAPROXEN (NOVITIUM PHARMA) APPROVAL= AP YEAR= 2024