e-Drug3D
421
DISOPYRAMIDE
INN
DISOPYRAMIDE
cas 3737-09-5
CLASS
CARDIOVASCULAR
ANTIARRHYTHMIC
SODIUM CHANNEL BLOCKERS
POTASSIUM CHANNEL BLOCKERS
ROUTE (list)
ORAL
ATC code
C01BA03
PK parameters
Tmax 2 HOUR
VD 33.8 LITER (65 KILOGRAM)
Cl 3.5 LITER / HOUR (65 KILOGRAM)
PPB 65 PERCENT
t1/2 6.7 HOUR
Solubility
FREELY SOLUBLE IN WATER
TARGET VOLTAGE GATED SODIUM CHANNEL
KV1.5
Sodium channel protein type 5 subunit alpha UNIPROT Q14524 SCN5A
Formula:
C21H29N3O
Calculated chemical properties:
MW 339.47
NB_atoms 25
XLogP 3.36
PSA 50.308
NB_HD 2
NB_HA 4
fsp3 0.43
Lipinski(0=no;1=yes) 1
NB_atoms 25
XLogP 3.36
PSA 50.308
NB_HD 2
NB_HA 4
fsp3 0.43
Lipinski(0=no;1=yes) 1
FDA
NDA 070138 (pdf not found) INN (DISOPYRAMIDE PHOSPHATE) DISOPYRAMIDE PHOSPHATE (MYLAN) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 070139 (pdf not found) INN (DISOPYRAMIDE PHOSPHATE) DISOPYRAMIDE PHOSPHATE (MYLAN) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 070240 (pdf not found) INN (DISOPYRAMIDE PHOSPHATE) DISOPYRAMIDE PHOSPHATE (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 070241 (pdf not found) INN (DISOPYRAMIDE PHOSPHATE) DISOPYRAMIDE PHOSPHATE (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 070940 (pdf not found) INN (DISOPYRAMIDE PHOSPHATE) DISOPYRAMIDE PHOSPHATE (SUPERPHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 070941 (pdf not found) INN (DISOPYRAMIDE PHOSPHATE) DISOPYRAMIDE PHOSPHATE (SUPERPHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 071190 (pdf not found) INN (DISOPYRAMIDE PHOSPHATE) DISOPYRAMIDE PHOSPHATE (INTERPHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 071191 (pdf not found) INN (DISOPYRAMIDE PHOSPHATE) DISOPYRAMIDE PHOSPHATE (INTERPHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 017447 (pdf not found) INN (DISOPYRAMIDE PHOSPHATE) NORPACE (PFIZER) APPROVAL= AP YEAR= 1977
NDA 018655 (pdf not found) INN (DISOPYRAMIDE PHOSPHATE) NORPACE CR (PFIZER) APPROVAL= AP YEAR= 1982
NDA 070101 (pdf not found) INN (DISOPYRAMIDE PHOSPHATE) DISOPYRAMIDE PHOSPHATE (TEVA) APPROVAL= AP YEAR= 1985
NDA 070102 (pdf not found) INN (DISOPYRAMIDE PHOSPHATE) DISOPYRAMIDE PHOSPHATE (TEVA) APPROVAL= AP YEAR= 1985
NDA 070173 (pdf not found) INN (DISOPYRAMIDE PHOSPHATE) DISOPYRAMIDE PHOSPHATE (DR REDDYS LABS SA) APPROVAL= AP YEAR= 1985
NDA 070174 (pdf not found) INN (DISOPYRAMIDE PHOSPHATE) DISOPYRAMIDE PHOSPHATE (MAYNE PHARMA) APPROVAL= AP YEAR= 1985 OBSOLETE
NDA 070186 (pdf not found) INN (DISOPYRAMIDE PHOSPHATE) DISOPYRAMIDE PHOSPHATE (IVAX SUB TEVA PHARMS) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 070187 (pdf not found) INN (DISOPYRAMIDE PHOSPHATE) DISOPYRAMIDE PHOSPHATE (IVAX SUB TEVA PHARMS) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 070351 (pdf not found) INN (DISOPYRAMIDE PHOSPHATE) DISOPYRAMIDE PHOSPHATE (SUN PHARM INDUSTRIES) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 070352 (pdf not found) INN (DISOPYRAMIDE PHOSPHATE) DISOPYRAMIDE PHOSPHATE (SUN PHARM INDUSTRIES) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 070470 (pdf not found) INN (DISOPYRAMIDE PHOSPHATE) DISOPYRAMIDE PHOSPHATE (RISING) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 070471 (pdf not found) INN (DISOPYRAMIDE PHOSPHATE) DISOPYRAMIDE PHOSPHATE (RISING) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 071200 (pdf not found) INN (DISOPYRAMIDE PHOSPHATE) DISOPYRAMIDE PHOSPHATE (NESHER PHARMS) APPROVAL= AP YEAR= 1987 DISCONTINUED
NDA 070138 (pdf not found) INN (DISOPYRAMIDE PHOSPHATE) DISOPYRAMIDE PHOSPHATE (MYLAN) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 070139 (pdf not found) INN (DISOPYRAMIDE PHOSPHATE) DISOPYRAMIDE PHOSPHATE (MYLAN) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 070240 (pdf not found) INN (DISOPYRAMIDE PHOSPHATE) DISOPYRAMIDE PHOSPHATE (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 070241 (pdf not found) INN (DISOPYRAMIDE PHOSPHATE) DISOPYRAMIDE PHOSPHATE (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 070940 (pdf not found) INN (DISOPYRAMIDE PHOSPHATE) DISOPYRAMIDE PHOSPHATE (SUPERPHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 070941 (pdf not found) INN (DISOPYRAMIDE PHOSPHATE) DISOPYRAMIDE PHOSPHATE (SUPERPHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 071190 (pdf not found) INN (DISOPYRAMIDE PHOSPHATE) DISOPYRAMIDE PHOSPHATE (INTERPHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 071191 (pdf not found) INN (DISOPYRAMIDE PHOSPHATE) DISOPYRAMIDE PHOSPHATE (INTERPHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 017447 (pdf not found) INN (DISOPYRAMIDE PHOSPHATE) NORPACE (PFIZER) APPROVAL= AP YEAR= 1977
NDA 018655 (pdf not found) INN (DISOPYRAMIDE PHOSPHATE) NORPACE CR (PFIZER) APPROVAL= AP YEAR= 1982
NDA 070101 (pdf not found) INN (DISOPYRAMIDE PHOSPHATE) DISOPYRAMIDE PHOSPHATE (TEVA) APPROVAL= AP YEAR= 1985
NDA 070102 (pdf not found) INN (DISOPYRAMIDE PHOSPHATE) DISOPYRAMIDE PHOSPHATE (TEVA) APPROVAL= AP YEAR= 1985
NDA 070173 (pdf not found) INN (DISOPYRAMIDE PHOSPHATE) DISOPYRAMIDE PHOSPHATE (DR REDDYS LABS SA) APPROVAL= AP YEAR= 1985
NDA 070174 (pdf not found) INN (DISOPYRAMIDE PHOSPHATE) DISOPYRAMIDE PHOSPHATE (MAYNE PHARMA) APPROVAL= AP YEAR= 1985 OBSOLETE
NDA 070186 (pdf not found) INN (DISOPYRAMIDE PHOSPHATE) DISOPYRAMIDE PHOSPHATE (IVAX SUB TEVA PHARMS) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 070187 (pdf not found) INN (DISOPYRAMIDE PHOSPHATE) DISOPYRAMIDE PHOSPHATE (IVAX SUB TEVA PHARMS) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 070351 (pdf not found) INN (DISOPYRAMIDE PHOSPHATE) DISOPYRAMIDE PHOSPHATE (SUN PHARM INDUSTRIES) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 070352 (pdf not found) INN (DISOPYRAMIDE PHOSPHATE) DISOPYRAMIDE PHOSPHATE (SUN PHARM INDUSTRIES) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 070470 (pdf not found) INN (DISOPYRAMIDE PHOSPHATE) DISOPYRAMIDE PHOSPHATE (RISING) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 070471 (pdf not found) INN (DISOPYRAMIDE PHOSPHATE) DISOPYRAMIDE PHOSPHATE (RISING) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 071200 (pdf not found) INN (DISOPYRAMIDE PHOSPHATE) DISOPYRAMIDE PHOSPHATE (NESHER PHARMS) APPROVAL= AP YEAR= 1987 DISCONTINUED