e-Drug3D

42

cas 50-81-7

CLASS

METABOLISM
VITAMIN C
ANTISCORBUTIC
ANTIOXIDANTS
FREE RADICAL SCAVENGERS

ROUTE (list)

INJECTION INTRAVENOUS ORAL

PK parameters

-

PDB
1F9G (CRYSTAL STRUCTURE OF STREPTOCOCCUS PNEUMONIAE HYALURONATE LYASE COCRYSTALLIZED WITH ASCORBIC ACID)

Ligand code = ASC (link to the list of PDB complexes)

Download experimental 3D coordinates of ASC with added hydrogens

MW 176.12
NB_atoms 12
XLogP -1.41
PSA 111.818
NB_HD 4
NB_HA 6
fsp3 0.50
Lipinski(0=no;1=yes) 1

FDA
NDA 018933 (pdf not found) INN (ASCORBIC ACID ; BIOTIN ; CYANOCOBALAMIN ; DEXPANTHENOL ; ERGOCALCIFEROL ; FOLIC ACID ; NIACINAMIDE ; PYRIDOXINE ; RIBOFLAVIN 5'-PHOSPHATE SODIUM ; THIAMINE ; VITAMIN A ; VITAMIN E) M.V.I.-12 LYOPHILIZED (TELIGENT) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 006071 (pdf not found) INN (ASCORBIC ACID ; BIOTIN ; CYANOCOBALAMIN ; DEXPANTHENOL ; ERGOCALCIFEROL ; FOLIC ACID ; NIACINAMIDE ; PYRIDOXINE HYDROCHLORIDE ; RIBOFLAVIN 5'-PHOSPHATE SODIUM ; THIAMINE HYDROCHLORIDE ; VITAMIN A PALMITATE ; VITAMIN E) BEROCCA PN (ROCHE) APPROVAL= AP YEAR= 1947 DISCONTINUED
NDA 008809 (pdf not found) INN (ASCORBIC ACID) M.V.I.-12 ADULT (HOSPIRA) APPROVAL= AP YEAR= 1953 DISCONTINUED
NDA 018440 (pdf not found) INN (ASCORBIC ACID ; BIOTIN ; CYANOCOBALAMIN ; DEXPANTHENOL ; ERGOCALCIFEROL ; FOLIC ACID ; NIACINAMIDE ; PYRIDOXINE HYDROCHLORIDE ; RIBOFLAVIN 5'-PHOSPHATE SODIUM ; THIAMINE HYDROCHLORIDE ; VITAMIN A ; VITAMIN E) M.V.C. 9+3 (ABRAXIS PHARM) APPROVAL= AP YEAR= 1981 DISCONTINUED
NDA 018439 (pdf not found) INN (ASCORBIC ACID ; BIOTIN ; CYANOCOBALAMIN ; DEXPANTHENOL ; ERGOCALCIFEROL ; FOLIC ACID ; NIACINAMIDE ; PYRIDOXINE HYDROCHLORIDE ; RIBOFLAVIN 5'-PHOSPHATE SODIUM ; THIAMINE HYDROCHLORIDE ; VITAMIN A ; VITAMIN E) MVC PLUS (WATSON LABS) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 018920 (pdf not found) INN (ASCORBIC ACID ; BIOTIN ; CYANOCOBALAMIN ; DEXPANTHENOL ; ERGOCALCIFEROL ; FOLIC ACID ; NIACINAMIDE ; PHYTONADIONE ; PYRIDOXINE HYDROCHLORIDE ; RIBOFLAVIN 5'-PHOSPHATE SODIUM ; THIAMINE HYDROCHLORIDE ; VITAMIN A ; VITAMIN E) M.V.I. PEDIATRIC (HOSPIRA) APPROVAL= AP YEAR= 1983 DISCONTINUED
NDA 020176 (pdf not found) INN (ASCORBIC ACID ; BIOTIN ; CYANOCOBALAMIN ; ERGOCALCIFEROL ; FOLIC ACID ; NIACINAMIDE ; PANTOTHENIC ACID ; PHYTONADIONE ; PYRIDOXINE ; RIBOFLAVIN ; THIAMINE ; VITAMIN A PALMITATE ; VITAMIN E) VITAPED (HOSPIRA) APPROVAL= AP YEAR= 1993 DISCONTINUED
NDA 021163 (pdf not found) INN (ALPHA-TOCOPHEROL ACETATE ; ASCORBIC ACID ; BIOTIN ; CHOLECALCIFEROL ; CYANOCOBALAMIN ; DEXPANTHENOL ; FOLIC ACID ; NIACINAMIDE ; PYRIDOXINE HYDROCHLORIDE ; RIBOFLAVIN 5'-PHOSPHATE SODIUM ; THIAMINE HYDROCHLORIDE ; VITAMIN A PALMITATE ; VITAMIN K) INFUVITE ADULT (SANDOZ CANADA INC) APPROVAL= AP YEAR= 2000
NDA 021265 (pdf not found) INN (ASCORBIC ACID ; BIOTIN ; CHOLECALCIFEROL ; CYANOCOBALAMIN ; DEXPANTHENOL ; FOLIC ACID ; NIACINAMIDE ; PYRIDOXINE ; RIBOFLAVIN ; THIAMINE ; TOCOPHEROL ACETATE ; VITAMIN A ; VITAMIN K) INFUVITE PEDIATRIC (SANDOZ CANADA INC) APPROVAL= AP YEAR= 2001
NDA 021559 (pdf not found) INN (ASCORBIC ACID) INFUVITE ADULT (SANDOZ INC) APPROVAL= AP YEAR= 2003 OBSOLETE
NDA 021625 (pdf not found) INN (ASCORBIC ACID ; BIOTIN ; CYANOCOBALAMIN ; DEXPANTHENOL ; ERGOCALCIFEROL ; FOLIC ACID ; NIACINAMIDE ; PYRIDOXINE HYDROCHLORIDE ; RIBOFLAVIN 5'-PHOSPHATE SODIUM ; THIAMINE HYDROCHLORIDE ; VITAMIN A ; VITAMIN E ; VITAMIN K) M.V.I. ADULT (HOSPIRA) APPROVAL= AP YEAR= 2004 DISCONTINUED
NDA 021643 (pdf not found) INN (ASCORBIC ACID ; BIOTIN ; CYANOCOBALAMIN ; DEXPANTHENOL ; ERGOCALCIFEROL ; FOLIC ACID ; NIACINAMIDE ; PYRIDOXINE HYDROCHLORIDE ; RIBOFLAVIN 5'-PHOSPHATE SODIUM ; THIAMINE HYDROCHLORIDE ; VITAMIN A ; VITAMIN E ; VITAMIN K) M.V.I. ADULT PHARMACY BULK PACKAGE (HOSPIRA) APPROVAL= AP YEAR= 2004 NEWAPPLICATION DISCONTINUED
NDA 021646 (pdf not found) INN (ASCORBIC ACID) INFUVITE PEDIATRIC PHARMACY BULK PACKAGE (SANDOZ INC) APPROVAL= AP YEAR= 2004 OBSOLETE
NDA 021881 (pdf not found) INN (ASCORBIC ACID ; POLYETHYLENE GLYCOL 3350 ; POTASSIUM CHLORIDE ; SODIUM ASCORBATE ; SODIUM CHLORIDE ; SODIUM SULFATE) MOVIPREP (SALIX PHARMS) APPROVAL= AP YEAR= 2006
NDA 090145 (pdf not found) INN (ASCORBIC ACID ; POLYETHYLENE GLYCOL 3350 ; POTASSIUM CHLORIDE ; SODIUM ASCORBATE ; SODIUM CHLORIDE ; SODIUM SULFATE) PEG-3350, SODIUM SULFATE, SODIUM CHLORIDE, POTASSIUM CHLORIDE, SODIUM ASCORBATE AND ASCORBIC ACID (NOVEL LABS INC) APPROVAL= AP YEAR= 2012
NDA 209112 (pdf not found) INN (ASCORBIC ACID) ASCOR (MCGUFF) APPROVAL= AP YEAR= 2017
NDA 209381 (pdf not found) INN (ASCORBIC ACID ; POLYETHYLENE GLYCOL 3350 ; POTASSIUM CHLORIDE ; SODIUM ASCORBATE ; SODIUM CHLORIDE ; SODIUM SULFATE) PLENVU (SALIX) APPROVAL= AP YEAR= 2018
NDA 207498 (pdf not found) INN (ASCORBIC ACID ; POLYETHYLENE GLYCOL 3350 ; POTASSIUM CHLORIDE ; SODIUM ASCORBATE ; SODIUM CHLORIDE ; SODIUM SULFATE) PEG-3350, SODIUM SULFATE, SODIUM CHLORIDE, POTASSIUM CHLORIDE, SODIUM ASCORBATE AND ASCORBIC ACID (TARO) APPROVAL= AP YEAR= 2024 DISCONTINUED
NDA 217131 (pdf not found) INN (ASCORBIC ACID) ASCORBIC ACID (FRESENIUS KABI USA) APPROVAL= AP YEAR= 2025