e-Drug3D

418

DINOPROST

DISCONTINUED

INN
DINOPROST

cas 551-11-1

CLASS

GENITO
PROSTAGLANDIN
OXYTOCIC
PROSTAGLANDIN E2 (PGE2)

ROUTE (list)

INJECTION

ATC code

G02AD01

PK parameters

Tmax 0.6 HOUR

Solubility

IN WATER 1.3 MILLIGRAM / MILLILITER

Target

TARGET PROSTAGLANDIN E2 RECEPTOR EP2

PDB
8IUK (CRYO-EM STRUCTURE OF THE PGF2-ALPHA-BOUND HUMAN PTGFR-GQ COMPLEX)

Download experimental 3D coordinates of UGU with added hydrogens

Prostaglandin F2-alpha receptor UNIPROT P43088 PTGFR

Download SDF file

2-amino-2-(hydroxymethyl)propane-1,3-diol; (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentyl]hept-5-enoic acid

Formula:
C20H34O5

Calculated chemical properties:

MW 353.46
NB_atoms 25
XLogP 1.71
PSA 95.454
NB_HD 3
NB_HA 5
fsp3 0.75
Lipinski(0=no;1=yes) 1

FDA
NDA 017434 (pdf not found) INN (DINOPROST TROMETHAMINE) PROSTIN F2 ALPHA (PHARMACIA AND UPJOHN) APPROVAL= AP YEAR= 1975 DISCONTINUED