e-Drug3D

415

PRAZEPAM

DISCONTINUED

INN
PRAZEPAM

(has an active metabolite)

cas 2955-38-6

CLASS

NERVOUS SYSTEM
ANXIOLYTIC
GABA MODULATORS
HYPNOTICS AND SEDATIVES

ROUTE (list)

ORAL

ATC code

N05BA11

PK parameters

Target

TARGET GAMMA-AMINOBUTYRIC-ACID RECEPTOR

DrugCentral

GABA-A receptor alpha-1,beta-2,gamma-2 UNIPROT P14867 GABRA1

Download SDF file

7-chloro-1-(cyclopropylmethyl)-5-phenyl-3H-1,4-benzodiazepin-2-one

Formula:
C19H17ClN2O

Calculated chemical properties:

MW 324.80
NB_atoms 23
XLogP 3.93
PSA 28.708
NB_HD 0
NB_HA 3
fsp3 0.26
Lipinski(0=no;1=yes) 1

FDA
NDA 017415 (pdf not found) INN (PRAZEPAM) CENTRAX (PARKE DAVIS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 070427 (pdf not found) INN (PRAZEPAM) PRAZEPAM (USL PHARMA) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 070428 (pdf not found) INN (PRAZEPAM) PRAZEPAM (USL PHARMA) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 018144 (pdf not found) INN (PRAZEPAM) CENTRAX (PARKE DAVIS) APPROVAL= AP YEAR= 1979 DISCONTINUED