e-Drug3D
410
TRIMETHOPRIM
INN
TRIMETHOPRIM
cas 738-70-5
CLASS
ANTIINFECTIVES
ANTIBIOTIC
ANTIBACTERIAL
ANTIMALARIALS
FOLIC ACID ANTAGONISTS
ROUTE (list)
ORAL INJECTION OPHTHALMIC
ATC code
J04AM08
J01EE02
J01EE05
J01EE07
J01EE01
J01EE03
J01EE04
J01EA01
PK parameters
Tmax 2.5 HOUR
VD 97.5 LITER (65 KILOGRAM)
Cl 8.1 LITER / HOUR (65 KILOGRAM)
PPB 44 PERCENT
t1/2 9 HOUR
TARGET DIHYDROFOLATE REDUCTASE
PDB
3FRB (S. AUREUS F98Y DHFR COMPLEXED WITH TMP)
Ligand code = TOP (link to the list of PDB complexes)
Download experimental 3D coordinates of TOP with added hydrogens
Dihydrofolate reductase UNIPROT P0ABQ4 folA
Formula:
C14H18N4O3
Calculated chemical properties:
MW 290.32
NB_atoms 21
XLogP 1.26
PSA 98.798
NB_HD 4
NB_HA 7
fsp3 0.29
Lipinski(0=no;1=yes) 1
NB_atoms 21
XLogP 1.26
PSA 98.798
NB_HD 4
NB_HA 7
fsp3 0.29
Lipinski(0=no;1=yes) 1
FDA
NDA 018946 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (HEATHER) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 070063 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULMEPRIM (USL PHARMA) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 070064 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULMEPRIM PEDIATRIC (USL PHARMA) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 070203 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (USL PHARMA) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 070204 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (USL PHARMA) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 070223 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (ABRAXIS PHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 071299 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (INTERPHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 071300 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (INTERPHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 071341 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOPRIM (QUAD PHARMS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 071556 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 071815 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) UROPLUS SS (SHIONOGI) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 071816 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) UROPLUS DS (SHIONOGI) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 072289 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) TRIMETH/SULFA (ALPHARMA US PHARMS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 072383 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (BEDFORD) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 072398 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) TRIMETH/SULFA (ALPHARMA US PHARMS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 072408 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (MARTEC USA LLC) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 072417 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM DOUBLE STRENGTH (MARTEC USA LLC) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 072769 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM DOUBLE STRENGTH (ROXANE) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 017376 (label) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SEPTRA (MONARCH PHARMS) APPROVAL= AP YEAR= 1973
NDA 017377 (label) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) BACTRIM (SUN PHARM INDUSTRIES) APPROVAL= AP YEAR= 1973
NDA 017560 (label) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) BACTRIM (SUN PHARM INDUSTRIES) APPROVAL= AP YEAR= 1975 DISCONTINUED
NDA 017598 (label) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SEPTRA (MONARCH PHARMS) APPROVAL= AP YEAR= 1975 DISCONTINUED
NDA 017943 (label) INN (TRIMETHOPRIM) PROLOPRIM (MONARCH PHARMS) APPROVAL= AP YEAR= 1980 DISCONTINUED
NDA 017952 (pdf not found) INN (TRIMETHOPRIM) TRIMPEX (ROCHE) APPROVAL= AP YEAR= 1980 DISCONTINUED
NDA 018242 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (TEVA) APPROVAL= AP YEAR= 1981 DISCONTINUED
NDA 018374 (label) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) BACTRIM (SUN PHARM INDS INC) APPROVAL= AP YEAR= 1981 DISCONTINUED
NDA 018452 (label) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SEPTRA (MONARCH PHARMS) APPROVAL= AP YEAR= 1981 DISCONTINUED
NDA 018598 (label) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (FOSUN PHARMA) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 018679 (label) INN (TRIMETHOPRIM) TRIMETHOPRIM (DR REDDYS LABS SA) APPROVAL= AP YEAR= 1982
NDA 018615 (label) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFATRIM PEDIATRIC (PHARM ASSOC) APPROVAL= AP YEAR= 1983
NDA 018812 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (TEVA) APPROVAL= AP YEAR= 1983 DISCONTINUED
NDA 018852 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (WATSON LABS) APPROVAL= AP YEAR= 1983 DISCONTINUED
NDA 018854 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM DOUBLE STRENGTH (WATSON LABS) APPROVAL= AP YEAR= 1983 DISCONTINUED
NDA 070000 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (WATSON LABS) APPROVAL= AP YEAR= 1984 DISCONTINUED
NDA 070002 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (WATSON LABS) APPROVAL= AP YEAR= 1984 DISCONTINUED
NDA 070006 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (MUTUAL PHARM) APPROVAL= AP YEAR= 1984 DISCONTINUED
NDA 070007 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM DOUBLE STRENGTH (MUTUAL PHARM) APPROVAL= AP YEAR= 1984 DISCONTINUED
NDA 070022 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOPRIM (NOVEL LABS INC) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 070028 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (ANI PHARMS) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 070030 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM SINGLE STRENGTH (HERITAGE PHARMA AVET) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 070032 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOPRIM-DS (NOVEL LABS INC) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 070034 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) COTRIM (TEVA) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 070037 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM DOUBLE STRENGTH (HERITAGE PHARMA AVET) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 070048 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) COTRIM D.S. (TEVA) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 070049 (pdf not found) INN (TRIMETHOPRIM) TRIMETHOPRIM (WATSON LABS) APPROVAL= AP YEAR= 1985
NDA 070065 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFATRIM-SS (SUPERPHARM) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 070066 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFATRIM-DS (SUPERPHARM) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 070215 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (PLIVA) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 070216 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (PLIVA) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 070494 (pdf not found) INN (TRIMETHOPRIM) TRIMETHOPRIM (SUN PHARM INDUSTRIES) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 070495 (pdf not found) INN (TRIMETHOPRIM) TRIMETHOPRIM (SUN PHARM INDUSTRIES) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 070889 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (FOSUN PHARMA) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 070890 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (FOSUN PHARMA) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 071016 (pdf not found) INN (TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (MUTUAL PHARM) APPROVAL= AP YEAR= 1986 DISCONTINUED OBSOLETE
NDA 071017 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (SUN PHARM INDUSTRIES) APPROVAL= AP YEAR= 1986
NDA 070627 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (HIKMA) APPROVAL= AP YEAR= 1987 DISCONTINUED
NDA 070628 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (HIKMA) APPROVAL= AP YEAR= 1987 DISCONTINUED
NDA 071259 (label) INN (TRIMETHOPRIM) TRIMETHOPRIM (TEVA) APPROVAL= AP YEAR= 1987 DISCONTINUED
NDA 050567 (pdf not found) INN (POLYMYXIN B SULFATE ; TRIMETHOPRIM SULFATE) POLYTRIM (ALLERGAN) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 072399 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) TRIMETH/SULFA (NASKA) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 072768 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (ROXANE) APPROVAL= AP YEAR= 1991 DISCONTINUED
NDA 073303 (label) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (TEVA PHARMS USA) APPROVAL= AP YEAR= 1991
NDA 073199 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (HOSPIRA) APPROVAL= AP YEAR= 1992 DISCONTINUED
NDA 074374 (pdf not found) INN (TRIMETHOPRIM HYDROCHLORIDE) PRIMSOL (PANGEA) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 064120 (pdf not found) INN (POLYMYXIN B SULFATE ; TRIMETHOPRIM SULFATE) TRIMETHOPRIM SULFATE AND POLYMYXIN B SULFATE (BAUSCH AND LOMB) APPROVAL= AP YEAR= 1997
NDA 074650 (label) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (HIKMA) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 064211 (pdf not found) INN (POLYMYXIN B SULFATE ; TRIMETHOPRIM SULFATE) TRIMETHOPRIM SULFATE AND POLYMYXIN B SULFATE (SANDOZ) APPROVAL= AP YEAR= 1998
NDA 065006 (pdf not found) INN (POLYMYXIN B SULFATE ; TRIMETHOPRIM SULFATE) TRIMETHOPRIM SULFATE AND POLYMYXIN B SULFATE (EPIC PHARMA LLC) APPROVAL= AP YEAR= 1998
NDA 074973 (label) INN (TRIMETHOPRIM HYDROCHLORIDE) PRIMSOL (PANGEA) APPROVAL= AP YEAR= 2000 DISCONTINUED
NDA 021105 (label) INN (PHENAZOPYRIDINE HYDROCHLORIDE ; SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM AND PHENAZOPYRIDINE HYDROCHLORIDE (ABLE) APPROVAL= AP YEAR= 2001 DISCONTINUED
NDA 076817 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (VISTA PHARMS) APPROVAL= AP YEAR= 2005
NDA 076899 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (AMNEAL PHARMS NY) APPROVAL= AP YEAR= 2005
NDA 077612 (label) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (PRASCO) APPROVAL= AP YEAR= 2006
NDA 077785 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (CHARTWELL MOLECULAR) APPROVAL= AP YEAR= 2007
NDA 078060 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (CHARTWELL MOLECULES) APPROVAL= AP YEAR= 2007
NDA 090624 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (AUROBINDO PHARMA) APPROVAL= AP YEAR= 2010
NDA 091348 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (AUROBINDO PHARMA) APPROVAL= AP YEAR= 2010
NDA 090828 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (GLENMARK PHARMS LTD) APPROVAL= AP YEAR= 2010
NDA 091437 (pdf not found) INN (TRIMETHOPRIM) TRIMETHOPRIM (NOVEL LABS INC) APPROVAL= AP YEAR= 2011
NDA 206607 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (MYLAN LABS LTD) APPROVAL= AP YEAR= 2017
NDA 212231 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (SOMERSET) APPROVAL= AP YEAR= 2019
NDA 212699 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (LUPIN LTD) APPROVAL= AP YEAR= 2021 DISCONTINUED
NDA 214330 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (NOVITIUM PHARMA) APPROVAL= AP YEAR= 2022
NDA 216393 (pdf not found) INN (TRIMETHOPRIM) TRIMETHOPRIM (NOVITIUM PHARMA) APPROVAL= AP YEAR= 2022
NDA 211572 (pdf not found) INN (POLYMYXIN B SULFATE ; TRIMETHOPRIM SULFATE) TRIMETHOPRIM SULFATE AND POLYMYXIN B SULFATE (SOMERSET THERAPS LLC) APPROVAL= AP YEAR= 2024
NDA 018946 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (HEATHER) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 070063 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULMEPRIM (USL PHARMA) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 070064 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULMEPRIM PEDIATRIC (USL PHARMA) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 070203 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (USL PHARMA) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 070204 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (USL PHARMA) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 070223 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (ABRAXIS PHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 071299 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (INTERPHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 071300 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (INTERPHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 071341 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOPRIM (QUAD PHARMS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 071556 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 071815 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) UROPLUS SS (SHIONOGI) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 071816 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) UROPLUS DS (SHIONOGI) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 072289 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) TRIMETH/SULFA (ALPHARMA US PHARMS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 072383 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (BEDFORD) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 072398 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) TRIMETH/SULFA (ALPHARMA US PHARMS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 072408 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (MARTEC USA LLC) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 072417 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM DOUBLE STRENGTH (MARTEC USA LLC) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 072769 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM DOUBLE STRENGTH (ROXANE) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 017376 (label) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SEPTRA (MONARCH PHARMS) APPROVAL= AP YEAR= 1973
NDA 017377 (label) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) BACTRIM (SUN PHARM INDUSTRIES) APPROVAL= AP YEAR= 1973
NDA 017560 (label) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) BACTRIM (SUN PHARM INDUSTRIES) APPROVAL= AP YEAR= 1975 DISCONTINUED
NDA 017598 (label) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SEPTRA (MONARCH PHARMS) APPROVAL= AP YEAR= 1975 DISCONTINUED
NDA 017943 (label) INN (TRIMETHOPRIM) PROLOPRIM (MONARCH PHARMS) APPROVAL= AP YEAR= 1980 DISCONTINUED
NDA 017952 (pdf not found) INN (TRIMETHOPRIM) TRIMPEX (ROCHE) APPROVAL= AP YEAR= 1980 DISCONTINUED
NDA 018242 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (TEVA) APPROVAL= AP YEAR= 1981 DISCONTINUED
NDA 018374 (label) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) BACTRIM (SUN PHARM INDS INC) APPROVAL= AP YEAR= 1981 DISCONTINUED
NDA 018452 (label) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SEPTRA (MONARCH PHARMS) APPROVAL= AP YEAR= 1981 DISCONTINUED
NDA 018598 (label) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (FOSUN PHARMA) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 018679 (label) INN (TRIMETHOPRIM) TRIMETHOPRIM (DR REDDYS LABS SA) APPROVAL= AP YEAR= 1982
NDA 018615 (label) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFATRIM PEDIATRIC (PHARM ASSOC) APPROVAL= AP YEAR= 1983
NDA 018812 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (TEVA) APPROVAL= AP YEAR= 1983 DISCONTINUED
NDA 018852 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (WATSON LABS) APPROVAL= AP YEAR= 1983 DISCONTINUED
NDA 018854 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM DOUBLE STRENGTH (WATSON LABS) APPROVAL= AP YEAR= 1983 DISCONTINUED
NDA 070000 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (WATSON LABS) APPROVAL= AP YEAR= 1984 DISCONTINUED
NDA 070002 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (WATSON LABS) APPROVAL= AP YEAR= 1984 DISCONTINUED
NDA 070006 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (MUTUAL PHARM) APPROVAL= AP YEAR= 1984 DISCONTINUED
NDA 070007 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM DOUBLE STRENGTH (MUTUAL PHARM) APPROVAL= AP YEAR= 1984 DISCONTINUED
NDA 070022 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOPRIM (NOVEL LABS INC) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 070028 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (ANI PHARMS) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 070030 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM SINGLE STRENGTH (HERITAGE PHARMA AVET) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 070032 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOPRIM-DS (NOVEL LABS INC) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 070034 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) COTRIM (TEVA) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 070037 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM DOUBLE STRENGTH (HERITAGE PHARMA AVET) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 070048 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) COTRIM D.S. (TEVA) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 070049 (pdf not found) INN (TRIMETHOPRIM) TRIMETHOPRIM (WATSON LABS) APPROVAL= AP YEAR= 1985
NDA 070065 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFATRIM-SS (SUPERPHARM) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 070066 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFATRIM-DS (SUPERPHARM) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 070215 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (PLIVA) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 070216 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (PLIVA) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 070494 (pdf not found) INN (TRIMETHOPRIM) TRIMETHOPRIM (SUN PHARM INDUSTRIES) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 070495 (pdf not found) INN (TRIMETHOPRIM) TRIMETHOPRIM (SUN PHARM INDUSTRIES) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 070889 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (FOSUN PHARMA) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 070890 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (FOSUN PHARMA) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 071016 (pdf not found) INN (TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (MUTUAL PHARM) APPROVAL= AP YEAR= 1986 DISCONTINUED OBSOLETE
NDA 071017 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (SUN PHARM INDUSTRIES) APPROVAL= AP YEAR= 1986
NDA 070627 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (HIKMA) APPROVAL= AP YEAR= 1987 DISCONTINUED
NDA 070628 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (HIKMA) APPROVAL= AP YEAR= 1987 DISCONTINUED
NDA 071259 (label) INN (TRIMETHOPRIM) TRIMETHOPRIM (TEVA) APPROVAL= AP YEAR= 1987 DISCONTINUED
NDA 050567 (pdf not found) INN (POLYMYXIN B SULFATE ; TRIMETHOPRIM SULFATE) POLYTRIM (ALLERGAN) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 072399 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) TRIMETH/SULFA (NASKA) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 072768 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (ROXANE) APPROVAL= AP YEAR= 1991 DISCONTINUED
NDA 073303 (label) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (TEVA PHARMS USA) APPROVAL= AP YEAR= 1991
NDA 073199 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (HOSPIRA) APPROVAL= AP YEAR= 1992 DISCONTINUED
NDA 074374 (pdf not found) INN (TRIMETHOPRIM HYDROCHLORIDE) PRIMSOL (PANGEA) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 064120 (pdf not found) INN (POLYMYXIN B SULFATE ; TRIMETHOPRIM SULFATE) TRIMETHOPRIM SULFATE AND POLYMYXIN B SULFATE (BAUSCH AND LOMB) APPROVAL= AP YEAR= 1997
NDA 074650 (label) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (HIKMA) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 064211 (pdf not found) INN (POLYMYXIN B SULFATE ; TRIMETHOPRIM SULFATE) TRIMETHOPRIM SULFATE AND POLYMYXIN B SULFATE (SANDOZ) APPROVAL= AP YEAR= 1998
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NDA 074973 (label) INN (TRIMETHOPRIM HYDROCHLORIDE) PRIMSOL (PANGEA) APPROVAL= AP YEAR= 2000 DISCONTINUED
NDA 021105 (label) INN (PHENAZOPYRIDINE HYDROCHLORIDE ; SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM AND PHENAZOPYRIDINE HYDROCHLORIDE (ABLE) APPROVAL= AP YEAR= 2001 DISCONTINUED
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NDA 214330 (pdf not found) INN (SULFAMETHOXAZOLE ; TRIMETHOPRIM) SULFAMETHOXAZOLE AND TRIMETHOPRIM (NOVITIUM PHARMA) APPROVAL= AP YEAR= 2022
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