e-Drug3D
400
MEGESTROL ACETATE
INN
MEGESTROL ACETATE
cas 595-33-5
CLASS
ANTINEOPLASTIC
TREATMENT OF ANOREXIA AND CACHEXIA
APPETITE ENHANCING
ROUTE (list)
ORAL
PK parameters
Tmax 5 HOUR
t1/2 35 HOUR
Solubility
2 MICROGRAM / MILLILITER
TARGET PROGESTERONE RECEPTOR
Progesterone receptor UNIPROT P06401 PGR
Formula:
C24H32O4
Calculated chemical properties:
MW 384.50
NB_atoms 28
XLogP 4.58
PSA 56.383
NB_HD 0
NB_HA 4
fsp3 0.71
Lipinski(0=no;1=yes) 1
NB_atoms 28
XLogP 4.58
PSA 56.383
NB_HD 0
NB_HA 4
fsp3 0.71
Lipinski(0=no;1=yes) 1
FDA
NDA 070646 (pdf not found) INN (MEGESTROL ACETATE) MEGESTROL ACETATE (USL PHARMA) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 070647 (pdf not found) INN (MEGESTROL ACETATE) MEGESTROL ACETATE (USL PHARMA) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 016979 (pdf not found) INN (MEGESTROL ACETATE) MEGACE (BRISTOL MYERS SQUIBB) APPROVAL= AP YEAR= 1971 DISCONTINUED
NDA 072422 (pdf not found) INN (MEGESTROL ACETATE) MEGESTROL ACETATE (STRIDES PHARMA) APPROVAL= AP YEAR= 1988
NDA 072423 (pdf not found) INN (MEGESTROL ACETATE) MEGESTROL ACETATE (STRIDES PHARMA) APPROVAL= AP YEAR= 1988
NDA 020264 (label) INN (MEGESTROL ACETATE) MEGACE (BRISTOL MYERS SQUIBB) APPROVAL= AP YEAR= 1993 DISCONTINUED
NDA 074458 (pdf not found) INN (MEGESTROL ACETATE) MEGESTROL ACETATE (HIKMA) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 074621 (pdf not found) INN (MEGESTROL ACETATE) MEGESTROL ACETATE (BARR) APPROVAL= AP YEAR= 1995
NDA 074745 (pdf not found) INN (MEGESTROL ACETATE) MEGESTROL ACETATE (TEVA) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 075671 (pdf not found) INN (MEGESTROL ACETATE) MEGESTROL ACETATE (STRIDES PHARMA) APPROVAL= AP YEAR= 2001
NDA 075997 (pdf not found) INN (MEGESTROL ACETATE) MEGESTROL ACETATE (HIKMA) APPROVAL= AP YEAR= 2002 DISCONTINUED
NDA 075681 (pdf not found) INN (MEGESTROL ACETATE) MEGESTROL ACETATE (TEVA PHARMS) APPROVAL= AP YEAR= 2003 DISCONTINUED
NDA 076721 (pdf not found) INN (MEGESTROL ACETATE) MEGESTROL ACETATE (PHARMOBEDIENT) APPROVAL= AP YEAR= 2004
NDA 021778 (label) INN (MEGESTROL ACETATE) MEGACE ES (ENDO OPERATIONS) APPROVAL= AP YEAR= 2005 DISCONTINUED
NDA 077404 (pdf not found) INN (MEGESTROL ACETATE) MEGESTROL ACETATE (NOVITIUM PHARMA) APPROVAL= AP YEAR= 2006
NDA 203139 (pdf not found) INN (MEGESTROL ACETATE) MEGESTROL ACETATE (TWI PHARMS) APPROVAL= AP YEAR= 2014
NDA 203960 (pdf not found) INN (MEGESTROL ACETATE) MEGESTROL ACETATE (HIKMA) APPROVAL= AP YEAR= 2017 DISCONTINUED
NDA 204688 (pdf not found) INN (MEGESTROL ACETATE) MEGESTROL ACETATE (CHARTWELL) APPROVAL= AP YEAR= 2017 DISCONTINUED
NDA 070646 (pdf not found) INN (MEGESTROL ACETATE) MEGESTROL ACETATE (USL PHARMA) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 070647 (pdf not found) INN (MEGESTROL ACETATE) MEGESTROL ACETATE (USL PHARMA) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 016979 (pdf not found) INN (MEGESTROL ACETATE) MEGACE (BRISTOL MYERS SQUIBB) APPROVAL= AP YEAR= 1971 DISCONTINUED
NDA 072422 (pdf not found) INN (MEGESTROL ACETATE) MEGESTROL ACETATE (STRIDES PHARMA) APPROVAL= AP YEAR= 1988
NDA 072423 (pdf not found) INN (MEGESTROL ACETATE) MEGESTROL ACETATE (STRIDES PHARMA) APPROVAL= AP YEAR= 1988
NDA 020264 (label) INN (MEGESTROL ACETATE) MEGACE (BRISTOL MYERS SQUIBB) APPROVAL= AP YEAR= 1993 DISCONTINUED
NDA 074458 (pdf not found) INN (MEGESTROL ACETATE) MEGESTROL ACETATE (HIKMA) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 074621 (pdf not found) INN (MEGESTROL ACETATE) MEGESTROL ACETATE (BARR) APPROVAL= AP YEAR= 1995
NDA 074745 (pdf not found) INN (MEGESTROL ACETATE) MEGESTROL ACETATE (TEVA) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 075671 (pdf not found) INN (MEGESTROL ACETATE) MEGESTROL ACETATE (STRIDES PHARMA) APPROVAL= AP YEAR= 2001
NDA 075997 (pdf not found) INN (MEGESTROL ACETATE) MEGESTROL ACETATE (HIKMA) APPROVAL= AP YEAR= 2002 DISCONTINUED
NDA 075681 (pdf not found) INN (MEGESTROL ACETATE) MEGESTROL ACETATE (TEVA PHARMS) APPROVAL= AP YEAR= 2003 DISCONTINUED
NDA 076721 (pdf not found) INN (MEGESTROL ACETATE) MEGESTROL ACETATE (PHARMOBEDIENT) APPROVAL= AP YEAR= 2004
NDA 021778 (label) INN (MEGESTROL ACETATE) MEGACE ES (ENDO OPERATIONS) APPROVAL= AP YEAR= 2005 DISCONTINUED
NDA 077404 (pdf not found) INN (MEGESTROL ACETATE) MEGESTROL ACETATE (NOVITIUM PHARMA) APPROVAL= AP YEAR= 2006
NDA 203139 (pdf not found) INN (MEGESTROL ACETATE) MEGESTROL ACETATE (TWI PHARMS) APPROVAL= AP YEAR= 2014
NDA 203960 (pdf not found) INN (MEGESTROL ACETATE) MEGESTROL ACETATE (HIKMA) APPROVAL= AP YEAR= 2017 DISCONTINUED
NDA 204688 (pdf not found) INN (MEGESTROL ACETATE) MEGESTROL ACETATE (CHARTWELL) APPROVAL= AP YEAR= 2017 DISCONTINUED