e-Drug3D
39
MEPHENYTOIN
DISCONTINUED
INN
MEPHENYTOIN
cas 50-12-4
CLASS
NERVOUS SYSTEM
ANTICONVULSANT
SODIUM CHANNEL BLOCKER
ROUTE (list)
ORAL
PK parameters
VD 97.5 LITER (65 KILOGRAM)
Cl 1.17 LITER / HOUR
t1/2 77 HOUR (PMID4032286)
TARGET NA+ CHANNELS (NAV)
Sodium channel alpha subunit UNIPROT P35498 SCN1A
Formula:
C12H14N2O2
Calculated chemical properties:
MW 218.25
NB_atoms 16
XLogP 1.47
PSA 50.106
NB_HD 1
NB_HA 4
fsp3 0.33
Lipinski(0=no;1=yes) 1
NB_atoms 16
XLogP 1.47
PSA 50.106
NB_HD 1
NB_HA 4
fsp3 0.33
Lipinski(0=no;1=yes) 1
FDA
NDA 006008 (pdf not found) INN (MEPHENYTOIN) MESANTOIN (NOVARTIS) APPROVAL= AP YEAR= 1946 DISCONTINUED
NDA 006008 (pdf not found) INN (MEPHENYTOIN) MESANTOIN (NOVARTIS) APPROVAL= AP YEAR= 1946 DISCONTINUED