e-Drug3D

381

cas 17617-23-1

CLASS

NERVOUS SYSTEM
HYPNOTIC
GABA MODULATORS
SEDATIVES
TREATMENT OF INSOMNIA

ROUTE (list)

ORAL

PK parameters

Tmax 0.66 HOUR
t1/2 2.3 HOUR

TARGET GAMMA-AMINOBUTYRIC-ACID RECEPTOR

PDB
2YOE (X-RAY STRUCTURE OF A PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI (ELIC) IN COMPLEX WITH GABA AND FLURAZEPAM)

Ligand code = FL7 (link to the list of PDB complexes)

Download experimental 3D coordinates of FL7 with added hydrogens

MW 387.87
NB_atoms 27
XLogP 4.00
PSA 34.626
NB_HD 0
NB_HA 4
fsp3 0.33
Lipinski(0=no;1=yes) 1

FDA
NDA 071551 (pdf not found) INN (FLURAZEPAM HYDROCHLORIDE) FLURAZEPAM HYDROCHLORIDE (PUREPAC PHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 071767 (pdf not found) INN (FLURAZEPAM HYDROCHLORIDE) FLURAZEPAM HYDROCHLORIDE (WARNER CHILCOTT) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 071768 (pdf not found) INN (FLURAZEPAM HYDROCHLORIDE) FLURAZEPAM HYDROCHLORIDE (WARNER CHILCOTT) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 071927 (pdf not found) INN (FLURAZEPAM HYDROCHLORIDE) FLURAZEPAM HYDROCHLORIDE (PUREPAC PHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 016721 (label) INN (FLURAZEPAM HYDROCHLORIDE) DALMANE (VALEANT PHARM INTL) APPROVAL= AP YEAR= 1970 NEWMOLECULARENTITY DISCONTINUED
NDA 070345 (pdf not found) INN (FLURAZEPAM HYDROCHLORIDE) FLURAZEPAM HYDROCHLORIDE (RISING) APPROVAL= AP YEAR= 1985
NDA 070444 (pdf not found) INN (FLURAZEPAM HYDROCHLORIDE) FLURAZEPAM HYDROCHLORIDE (ESJAY PHARMA) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 070445 (pdf not found) INN (FLURAZEPAM HYDROCHLORIDE) FLURAZEPAM HYDROCHLORIDE (ESJAY PHARMA) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 070454 (pdf not found) INN (FLURAZEPAM HYDROCHLORIDE) FLURAZEPAM HYDROCHLORIDE (SUN PHARM INDUSTRIES) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 070455 (pdf not found) INN (FLURAZEPAM HYDROCHLORIDE) FLURAZEPAM HYDROCHLORIDE (SUN PHARM INDUSTRIES) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 071068 (pdf not found) INN (FLURAZEPAM HYDROCHLORIDE) FLURAZEPAM HYDROCHLORIDE (CHARTWELL RX) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 071107 (pdf not found) INN (FLURAZEPAM HYDROCHLORIDE) FLURAZEPAM HYDROCHLORIDE (HIKMA INTL PHARMS) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 071108 (pdf not found) INN (FLURAZEPAM HYDROCHLORIDE) FLURAZEPAM HYDROCHLORIDE (HIKMA) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 071205 (pdf not found) INN (FLURAZEPAM HYDROCHLORIDE) FLURAZEPAM HYDROCHLORIDE (CHARTWELL RX) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 070562 (pdf not found) INN (FLURAZEPAM HYDROCHLORIDE) FLURAZEPAM HYDROCHLORIDE (USL PHARMA) APPROVAL= AP YEAR= 1987 DISCONTINUED
NDA 070563 (pdf not found) INN (FLURAZEPAM HYDROCHLORIDE) FLURAZEPAM HYDROCHLORIDE (USL PHARMA) APPROVAL= AP YEAR= 1987 DISCONTINUED
NDA 071660 (pdf not found) INN (FLURAZEPAM HYDROCHLORIDE) FLURAZEPAM HYDROCHLORIDE (SUPERPHARM) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 071808 (pdf not found) INN (FLURAZEPAM HYDROCHLORIDE) FLURAZEPAM HYDROCHLORIDE (HALSEY) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 071809 (pdf not found) INN (FLURAZEPAM HYDROCHLORIDE) FLURAZEPAM HYDROCHLORIDE (HALSEY) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 071659 (pdf not found) INN (FLURAZEPAM HYDROCHLORIDE) FLURAZEPAM HYDROCHLORIDE (SUPERPHARM) APPROVAL= AP YEAR= 1989 DISCONTINUED
NDA 072368 (pdf not found) INN (FLURAZEPAM HYDROCHLORIDE) FLURAZEPAM HYDROCHLORIDE (CHARTWELL RX) APPROVAL= AP YEAR= 1989
NDA 072369 (pdf not found) INN (FLURAZEPAM HYDROCHLORIDE) FLURAZEPAM HYDROCHLORIDE (CHARTWELL RX) APPROVAL= AP YEAR= 1989
NDA 071716 (pdf not found) INN (FLURAZEPAM HYDROCHLORIDE) FLURAZEPAM HYDROCHLORIDE (AUROLIFE PHARMA LLC) APPROVAL= AP YEAR= 1991 DISCONTINUED OBSOLETE
NDA 071717 (pdf not found) INN (FLURAZEPAM HYDROCHLORIDE) FLURAZEPAM HYDROCHLORIDE (RISING) APPROVAL= AP YEAR= 1991 DISCONTINUED