e-Drug3D

38

cas 54-05-7

CLASS

ANTIPARASITIC
ANTIMALARIALS

ROUTE (list)

ORAL INJECTION

PK parameters

VD 9100 LITER (65 KILOGRAM)
Cl 16 LITER / HOUR (65 KILOGRAM)
PPB 55 PERCENT
t1/2 570 HOUR

TARGET DNA
LACTATE DEHYDROGENASE

PDB
4V2O (STRUCTURE OF SAPOSIN B IN COMPLEX WITH CHLOROQUINE)

Ligand code = CLQ (link to the list of PDB complexes)

Download experimental 3D coordinates of CLQ with added hydrogens

MW 319.87
NB_atoms 22
XLogP 4.81
PSA 26.184
NB_HD 1
NB_HA 3
fsp3 0.50
Lipinski(0=no;1=yes) 1

FDA
NDA 080886 (pdf not found) INN (CHLOROQUINE PHOSPHATE) CHLOROQUINE PHOSPHATE (PUREPAC PHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 087228 (pdf not found) INN (CHLOROQUINE PHOSPHATE) CHLOROQUINE PHOSPHATE (MD PHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 006002 (label) INN (CHLOROQUINE PHOSPHATE) ARALEN (SANOFI AVENTIS US) APPROVAL= AP YEAR= 1949 DISCONTINUED
NDA 014860 (pdf not found) INN (CHLOROQUINE PHOSPHATE ; PRIMAQUINE PHOSPHATE) ARALEN PHOSPHATE W/ PRIMAQUINE PHOSPHATE (SANOFI AVENTIS US) APPROVAL= AP YEAR= 1968 DISCONTINUED
NDA 080880 (pdf not found) INN (CHLOROQUINE PHOSPHATE) CHLOROQUINE PHOSPHATE (IMPAX LABS) APPROVAL= AP YEAR= 1974
NDA 083082 (label) INN (CHLOROQUINE PHOSPHATE) CHLOROQUINE PHOSPHATE (HIKMA PHARMS) APPROVAL= AP YEAR= 1975 DISCONTINUED
NDA 087504 (pdf not found) INN (CHLOROQUINE PHOSPHATE) CHLOROQUINE PHOSPHATE (TEVA) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 087979 (pdf not found) INN (CHLOROQUINE PHOSPHATE) CHLOROQUINE PHOSPHATE (WATSON LABS) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 088030 (pdf not found) INN (CHLOROQUINE PHOSPHATE) CHLOROQUINE PHOSPHATE (WATSON LABS) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 040516 (pdf not found) INN (CHLOROQUINE PHOSPHATE) CHLOROQUINE PHOSPHATE (IMPAX LABS) APPROVAL= AP YEAR= 2003
NDA 090249 (pdf not found) INN (CHLOROQUINE PHOSPHATE) CHLOROQUINE PHOSPHATE (IPCA LABS LTD) APPROVAL= AP YEAR= 2009 DISCONTINUED
NDA 090610 (label) INN (CHLOROQUINE PHOSPHATE) CHLOROQUINE PHOSPHATE (IPCA LABS LTD) APPROVAL= AP YEAR= 2009 DISCONTINUED
NDA 090612 (pdf not found) INN (CHLOROQUINE PHOSPHATE) CHLOROQUINE PHOSPHATE (NATCO PHARMA LTD) APPROVAL= AP YEAR= 2011
NDA 091621 (pdf not found) INN (CHLOROQUINE PHOSPHATE) CHLOROQUINE PHOSPHATE (NATCO PHARMA LTD) APPROVAL= AP YEAR= 2011
NDA 214756 (pdf not found) INN (CHLOROQUINE PHOSPHATE) CHLOROQUINE PHOSPHATE (SUVEN PHARMS) APPROVAL= AP YEAR= 2021