e-Drug3D

373

FLUMETHASONE PIVALATE

DISCONTINUED

INN
FLUMETHASONE PIVALATE

cas 2002-29-1

CLASS

DERMATOLOGICALS
GLUCOCORTICOID
ANTI-INFLAMMATORY AGENTS
ANTIPRURITICS

ROUTE (list)

TOPICAL

ATC code

C05AA10
D07AC04
S01BA15
S02BA08
D07CC02
S01CA10
S02CA05
D07BC02

PK parameters

Target

TARGET GLUCOCORTICOID RECEPTOR

DrugCentral

Glucocorticoid receptor UNIPROT P04150 NR3C1

Download SDF file

[2-[(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] 2,2-dimethylpropanoate

Formula:
C27H36F2O6

Calculated chemical properties:

MW 494.56
NB_atoms 35
XLogP 3.44
PSA 87.133
NB_HD 2
NB_HA 6
fsp3 0.74
Lipinski(0=no;1=yes) 1

FDA
NDA 016379 (pdf not found) INN (FLUMETHASONE PIVALATE) LOCORTEN (NOVARTIS) APPROVAL= - YEAR= 0 DISCONTINUED