e-Drug3D

361

THIABENDAZOLE

DISCONTINUED

INN
THIABENDAZOLE

cas 148-79-8

CLASS

ANTIPARASITIC
ANTHELMINTIC
ANTINEMATODAL AGENTS

ROUTE (list)

ORAL

ATC code

D01AC06
P02CA02

PK parameters

Tmax 1.5 HOUR

Solubility

PRACTICALLY INSOLUBLE IN WATER

Target

TARGET FUMARATE REDUCTASE

PDB
1YVM (E. COLI METHIONINE AMINOPEPTIDASE IN COMPLEX WITH THIABENDAZOLE)

Ligand code = TMG (link to the list of PDB complexes)

Download experimental 3D coordinates of TMG with added hydrogens

DrugCentral

Tubulin UNIPROT C4PKY4

Tubulin UNIPROT F1L005

Download SDF file

2-(1,3-thiazol-4-yl)-1H-benzimidazole

Formula:
C10H7N3S

Calculated chemical properties:

MW 201.26
NB_atoms 14
XLogP 2.69
PSA 34.869
NB_HD 1
NB_HA 3
fsp3 0.00
Lipinski(0=no;1=yes) 1

FDA
NDA 016096 (pdf not found) INN (THIABENDAZOLE) MINTEZOL (MERCK SHARP DOHME) APPROVAL= AP YEAR= 1967 DISCONTINUED
NDA 016097 (pdf not found) INN (THIABENDAZOLE) MINTEZOL (MERCK SHARP DOHME) APPROVAL= AP YEAR= 1967 DISCONTINUED