e-Drug3D

359

cas 315-30-0

CLASS

MUSCULO-SKELETAL SYSTEM
TREATMENT OF HYPERURICEMIA (GOUT SUPPRESSANT)
XANTHINE OXIDASE INHIBITOR
ANTIMETABOLITES
ACTS ON PURINE CATABOLISM AND REDUCES THE PRODUCTION OF URIC ACID

ROUTE (list)

ORAL INJECTION

PK parameters

F 90 PERCENT
Tmax 1.5 HOUR
VD 37.7 LITER (65 KILOGRAM)
Cl 42.9 LITER / HOUR (65 KILOGRAM)
PPB 3 PERCENT
t1/2 1.5 HOUR

MW 136.12
NB_atoms 10
XLogP -0.40
PSA 69.3
NB_HD 2
NB_HA 5
fsp3 0.00
Lipinski(0=no;1=yes) 1

FDA
NDA 018241 (pdf not found) INN (ALLOPURINOL) ALLOPURINOL (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 018785 (pdf not found) INN (ALLOPURINOL) ALLOPURINOL (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 070579 (pdf not found) INN (ALLOPURINOL) ALLOPURINOL (PUREPAC PHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 070580 (pdf not found) INN (ALLOPURINOL) ALLOPURINOL (PUREPAC PHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 070950 (pdf not found) INN (ALLOPURINOL) ALLOPURINOL (SUPERPHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 070951 (pdf not found) INN (ALLOPURINOL) ALLOPURINOL (SUPERPHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 016084 (label) INN (ALLOPURINOL) ZYLOPRIM (CASPER PHARMA LLC) APPROVAL= AP YEAR= 1966 NEWMOLECULARENTITY
NDA 018297 (pdf not found) INN (ALLOPURINOL) LOPURIN (ABBOTT) APPROVAL= AP YEAR= 1980 DISCONTINUED
NDA 018832 (label) INN (ALLOPURINOL) ALLOPURINOL (WATSON LABS) APPROVAL= AP YEAR= 1984
NDA 018877 (label) INN (ALLOPURINOL) ALLOPURINOL (WATSON LABS) APPROVAL= AP YEAR= 1984
NDA 070147 (pdf not found) INN (ALLOPURINOL) ALLOPURINOL (PURACAP PHARM) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 070150 (pdf not found) INN (ALLOPURINOL) ALLOPURINOL (PURACAP PHARM) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 070268 (pdf not found) INN (ALLOPURINOL) ALLOPURINOL (AIPING PHARM INC) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 070269 (pdf not found) INN (ALLOPURINOL) ALLOPURINOL (SANDOZ) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 070466 (pdf not found) INN (ALLOPURINOL) ALLOPURINOL (MUTUAL PHARM) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 070467 (pdf not found) INN (ALLOPURINOL) ALLOPURINOL (MUTUAL PHARM) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 018659 (pdf not found) INN (ALLOPURINOL) ALLOPURINOL (MYLAN) APPROVAL= AP YEAR= 1986
NDA 071449 (pdf not found) INN (ALLOPURINOL) ALLOPURINOL (MUTUAL PHARM) APPROVAL= AP YEAR= 1987 OBSOLETE
NDA 071450 (pdf not found) INN (ALLOPURINOL) ALLOPURINOL (SUN PHARM INDUSTRIES) APPROVAL= AP YEAR= 1987
NDA 071586 (pdf not found) INN (ALLOPURINOL) LOPURIN (DR REDDYS) APPROVAL= AP YEAR= 1987
NDA 071587 (pdf not found) INN (ALLOPURINOL) LOPURIN (DR REDDYS) APPROVAL= AP YEAR= 1987
NDA 020298 (label) INN (ALLOPURINOL SODIUM) ALOPRIM (MYLAN) APPROVAL= AP YEAR= 1996
NDA 075798 (pdf not found) INN (ALLOPURINOL) ALLOPURINOL (PH HEALTH) APPROVAL= AP YEAR= 2003
NDA 076870 (pdf not found) INN (ALLOPURINOL SODIUM) ALLOPURINOL SODIUM (HIKMA) APPROVAL= AP YEAR= 2004
NDA 077353 (pdf not found) INN (ALLOPURINOL) ALLOPURINOL (CHARTWELL) APPROVAL= AP YEAR= 2005
NDA 078253 (pdf not found) INN (ALLOPURINOL) ALLOPURINOL (NORTHSTAR HLTHCARE) APPROVAL= AP YEAR= 2007
NDA 078390 (pdf not found) INN (ALLOPURINOL) ALLOPURINOL (SUN PHARM INDS INC) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 090637 (pdf not found) INN (ALLOPURINOL) ALLOPURINOL (IPCA LABS LTD) APPROVAL= AP YEAR= 2011 DISCONTINUED
NDA 203154 (pdf not found) INN (ALLOPURINOL) ALLOPURINOL (ACCORD HLTHCARE) APPROVAL= AP YEAR= 2013
NDA 204467 (pdf not found) INN (ALLOPURINOL) ALLOPURINOL (INDOCO) APPROVAL= AP YEAR= 2016
NDA 209203 (label) INN (ALLOPURINOL ; LESINURAD) DUZALLO (IRONWOOD PHARMS INC) APPROVAL= AP YEAR= 2017 DISCONTINUED
NDA 210117 (pdf not found) INN (ALLOPURINOL) ALLOPURINOL (ZYDUS PHARMS) APPROVAL= AP YEAR= 2017
NDA 211820 (pdf not found) INN (ALLOPURINOL) ALLOPURINOL (UNICHEM) APPROVAL= AP YEAR= 2019
NDA 212363 (pdf not found) INN (ALLOPURINOL SODIUM) ALLOPURINOL SODIUM (GLAND) APPROVAL= AP YEAR= 2022
NDA 214443 (pdf not found) INN (ALLOPURINOL) ALLOPURINOL (HARMAN FINOCHEM) APPROVAL= AP YEAR= 2022
NDA 211807 (pdf not found) INN (ALLOPURINOL) ALLOPURINOL (LUPIN LTD) APPROVAL= AP YEAR= 2023 DISCONTINUED
NDA 217748 (pdf not found) INN (ALLOPURINOL) ALLOPURINOL (HETERO LABS LTD V) APPROVAL= AP YEAR= 2023
NDA 215091 (pdf not found) INN (ALLOPURINOL) ALLOPURINOL (AUROBINDO PHARMA LTD) APPROVAL= AP YEAR= 2025