e-Drug3D
348
TOLAZAMIDE
DISCONTINUED
INN
TOLAZAMIDE
cas 1156-19-0
CLASS
METABOLISM
ANTIDIABETIC
HYPOGLYCEMIC AGENTS
SULFONYLUREA CLASS
ROUTE (list)
ORAL
ATC code
A10BB05
PK parameters
Tmax 3.5 HOUR
t1/2 7 HOUR
Solubility
27.8 MILLIGRAM / 100 MILLILITER
TARGET ATP-SENSITIVE POTASSIUM CHANNEL OF THE PANCREATIC B-CELL
Sulfonylurea receptor 1, Kir6.2 UNIPROT Q09428 ABCC8
Formula:
C14H21N3O3S
Calculated chemical properties:
MW 311.41
NB_atoms 21
XLogP 1.77
PSA 76.05
NB_HD 2
NB_HA 6
fsp3 0.50
Lipinski(0=no;1=yes) 1
NB_atoms 21
XLogP 1.77
PSA 76.05
NB_HD 2
NB_HA 6
fsp3 0.50
Lipinski(0=no;1=yes) 1
FDA
NDA 070166 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (DURAMED PHARMS BARR) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 070168 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (USL PHARMA) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 070169 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (USL PHARMA) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 070242 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 070243 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 070244 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 070764 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (SUPERPHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 071270 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (INTERPHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 071271 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (INTERPHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 071355 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (USL PHARMA) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 015500 (pdf not found) INN (TOLAZAMIDE) TOLINASE (PHARMACIA AND UPJOHN) APPROVAL= AP YEAR= 1966 NEWMOLECULARENTITY DISCONTINUED
NDA 018894 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (COSETTE) APPROVAL= AP YEAR= 1984 DISCONTINUED
NDA 070159 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (PAR PHARM) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 070160 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (PAR PHARM) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 070161 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (PAR PHARM) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 070162 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (BARR) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 070163 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (BARR) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 070164 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (BARR) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 070165 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (DURAMED PHARMS BARR) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 070167 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (DURAMED PHARMS BARR) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 070259 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (NATCO) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 070289 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (CHARTWELL RX) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 070290 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (CHARTWELL RX) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 070513 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (WATSON LABS) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 070514 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (WATSON LABS) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 070515 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (WATSON LABS) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 070763 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (SUPERPHARM) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 071357 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (SUN PHARM INDUSTRIES) APPROVAL= AP YEAR= 1987 DISCONTINUED
NDA 071358 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (SUN PHARM INDUSTRIES) APPROVAL= AP YEAR= 1987 DISCONTINUED
NDA 071359 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (SUN PHARM INDUSTRIES) APPROVAL= AP YEAR= 1987 DISCONTINUED
NDA 071633 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (CHARTWELL RX) APPROVAL= AP YEAR= 1987 DISCONTINUED
NDA 070166 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (DURAMED PHARMS BARR) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 070168 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (USL PHARMA) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 070169 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (USL PHARMA) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 070242 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 070243 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 070244 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 070764 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (SUPERPHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 071270 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (INTERPHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 071271 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (INTERPHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 071355 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (USL PHARMA) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 015500 (pdf not found) INN (TOLAZAMIDE) TOLINASE (PHARMACIA AND UPJOHN) APPROVAL= AP YEAR= 1966 NEWMOLECULARENTITY DISCONTINUED
NDA 018894 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (COSETTE) APPROVAL= AP YEAR= 1984 DISCONTINUED
NDA 070159 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (PAR PHARM) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 070160 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (PAR PHARM) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 070161 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (PAR PHARM) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 070162 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (BARR) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 070163 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (BARR) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 070164 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (BARR) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 070165 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (DURAMED PHARMS BARR) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 070167 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (DURAMED PHARMS BARR) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 070259 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (NATCO) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 070289 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (CHARTWELL RX) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 070290 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (CHARTWELL RX) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 070513 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (WATSON LABS) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 070514 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (WATSON LABS) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 070515 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (WATSON LABS) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 070763 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (SUPERPHARM) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 071357 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (SUN PHARM INDUSTRIES) APPROVAL= AP YEAR= 1987 DISCONTINUED
NDA 071358 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (SUN PHARM INDUSTRIES) APPROVAL= AP YEAR= 1987 DISCONTINUED
NDA 071359 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (SUN PHARM INDUSTRIES) APPROVAL= AP YEAR= 1987 DISCONTINUED
NDA 071633 (pdf not found) INN (TOLAZAMIDE) TOLAZAMIDE (CHARTWELL RX) APPROVAL= AP YEAR= 1987 DISCONTINUED