e-Drug3D

344

cas 721-50-6

CLASS

NERVOUS SYSTEM
ANESTHETIC (LOCAL)

ROUTE (list)

INJECTION TOPICAL PERIODONTAL

PK parameters

VD 156 LITER (60 KILOGRAM)
Cl 142 LITER / HOUR
PPB 40 PERCENT
t1/2 1.6 HOUR

MW 220.31
NB_atoms 16
XLogP 2.32
PSA 37.743
NB_HD 2
NB_HA 3
fsp3 0.46
Lipinski(0=no;1=yes) 1

FDA
NDA 014763 (pdf not found) INN (PRILOCAINE HYDROCHLORIDE) CITANEST (ASTRAZENECA) APPROVAL= AP YEAR= 1965 NEWMOLECULARENTITY DISCONTINUED
NDA 021382 (label) INN (PRILOCAINE HYDROCHLORIDE) CITANEST PLAIN DENTAL (DENTSPLY PHARM) APPROVAL= AP YEAR= 1965 DISCONTINUED
NDA 021383 (label) INN (EPINEPHRINE BITARTRATE ; PRILOCAINE HYDROCHLORIDE) CITANEST FORTE DENTAL (DENTSPLY PHARM) APPROVAL= AP YEAR= 1965
NDA 019941 (label) INN (LIDOCAINE ; PRILOCAINE) EMLA (TEVA BRANDED PHARM) APPROVAL= AP YEAR= 1992 DISCONTINUED
NDA 020962 (pdf not found) INN (LIDOCAINE ; PRILOCAINE) EMLA (ASTRAZENECA) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 021451 (label) INN (LIDOCAINE ; PRILOCAINE) ORAQIX (DENTSPLY PHARM) APPROVAL= AP YEAR= 2003
NDA 076290 (pdf not found) INN (LIDOCAINE ; PRILOCAINE) LIDOCAINE AND PRILOCAINE (HIKMA) APPROVAL= AP YEAR= 2003 DISCONTINUED
NDA 076320 (pdf not found) INN (LIDOCAINE ; PRILOCAINE) LIDOCAINE AND PRILOCAINE (ENCUBE) APPROVAL= AP YEAR= 2003
NDA 076453 (pdf not found) INN (LIDOCAINE ; PRILOCAINE) LIDOCAINE AND PRILOCAINE (FOUGERA PHARMS) APPROVAL= AP YEAR= 2003
NDA 079235 (pdf not found) INN (PRILOCAINE HYDROCHLORIDE) PRILOCAINE HYDROCHLORIDE (SEPTODONT INC) APPROVAL= AP YEAR= 2010
NDA 078959 (pdf not found) INN (EPINEPHRINE BITARTRATE ; PRILOCAINE HYDROCHLORIDE) PRILOCAINE HYDROCHLORIDE AND EPINEPHRINE BITARTRATE (SEPTODONT INC) APPROVAL= AP YEAR= 2011
NDA 205887 (pdf not found) INN (LIDOCAINE ; PRILOCAINE) LIDOCAINE AND PRILOCAINE (PAI HOLDINGS PHARM) APPROVAL= AP YEAR= 2018 DISCONTINUED
NDA 213253 (pdf not found) INN (LIDOCAINE ; PRILOCAINE) LIDOCAINE AND PRILOCAINE (RHODES PHARMS) APPROVAL= AP YEAR= 2020 DISCONTINUED
NDA 212482 (pdf not found) INN (LIDOCAINE ; PRILOCAINE) LIDOCAINE AND PRILOCAINE (PADAGIS US) APPROVAL= AP YEAR= 2021
NDA 213923 (pdf not found) INN (LIDOCAINE ; PRILOCAINE) LIDOCAINE AND PRILOCAINE (ALEMBIC) APPROVAL= AP YEAR= 2022
NDA 219120 (pdf not found) INN (LIDOCAINE ; PRILOCAINE) LIDOCAINE AND PRILOCAINE (ZYDUS LIFESCIENCES) APPROVAL= AP YEAR= 2024