e-Drug3D

332

cas 616-91-1

CLASS

RESPIRATORY SYSTEM
MUCOLYTIC
ANTIVIRAL AGENTS
EXPECTORANTS
TREATMENT OF ACETAMINOPHEN OVERDOSE
MAINTAINING OR RESTORING THE GLUTATHIONE LEVELS

ROUTE (list)

INHALATION ORAL INTRAVENOUS

PK parameters

VD 30.5 LITER (65 KILOGRAM)
Cl 7.15 LITER / HOUR (65 KILOGRAM)
PPB 83 PERCENT
t1/2 5.6 HOUR

-

PDB
2J2P (L-FICOLIN COMPLEXED TO N-ACETYL-CYSTEIN (150MM))

Ligand code = SC2 (link to the list of PDB complexes)

Download experimental 3D coordinates of SC2 with added hydrogens

MW 162.19
NB_atoms 10
XLogP -1.83
PSA 61.324
NB_HD 1
NB_HA 4
fsp3 0.60
Lipinski(0=no;1=yes) 1

FDA
NDA 017366 (pdf not found) INN (ACETYLCYSTEINE ; ISOPROTERENOL HYDROCHLORIDE) MUCOMYST W/ ISOPROTERENOL (MEAD JOHNSON) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 071740 (pdf not found) INN (ACETYLCYSTEINE) ACETYLCYSTEINE (QUAD PHARMS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 071741 (pdf not found) INN (ACETYLCYSTEINE) ACETYLCYSTEINE (QUAD PHARMS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 013601 (pdf not found) INN (ACETYLCYSTEINE) MUCOMYST (APOTHECON) APPROVAL= AP YEAR= 1963 DISCONTINUED
NDA 070575 (pdf not found) INN (ACETYLCYSTEINE) MUCOSIL-10 (DEY) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 070576 (pdf not found) INN (ACETYLCYSTEINE) MUCOSIL-20 (DEY) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 072323 (pdf not found) INN (ACETYLCYSTEINE) ACETYLCYSTEINE (ROXANE) APPROVAL= AP YEAR= 1992 DISCONTINUED
NDA 072324 (pdf not found) INN (ACETYLCYSTEINE) ACETYLCYSTEINE (ROXANE) APPROVAL= AP YEAR= 1992 DISCONTINUED
NDA 072621 (pdf not found) INN (ACETYLCYSTEINE) ACETYLCYSTEINE (ROXANE) APPROVAL= AP YEAR= 1992 DISCONTINUED
NDA 072622 (pdf not found) INN (ACETYLCYSTEINE) ACETYLCYSTEINE (ROXANE) APPROVAL= AP YEAR= 1992 DISCONTINUED
NDA 073664 (pdf not found) INN (ACETYLCYSTEINE) ACETYLCYSTEINE (HOSPIRA) APPROVAL= AP YEAR= 1994
NDA 074037 (pdf not found) INN (ACETYLCYSTEINE) ACETYLCYSTEINE (HOSPIRA) APPROVAL= AP YEAR= 1994
NDA 072489 (pdf not found) INN (ACETYLCYSTEINE) ACETYLCYSTEINE (AM REGENT) APPROVAL= AP YEAR= 1995
NDA 072547 (pdf not found) INN (ACETYLCYSTEINE) ACETYLCYSTEINE (AM REGENT) APPROVAL= AP YEAR= 1995
NDA 071364 (pdf not found) INN (ACETYLCYSTEINE) ACETYLCYSTEINE (HOSPIRA) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 071365 (pdf not found) INN (ACETYLCYSTEINE) ACETYLCYSTEINE (HOSPIRA) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 021539 (label) INN (ACETYLCYSTEINE) ACETADOTE (CUMBERLAND PHARMS) APPROVAL= AP YEAR= 2004
NDA 200644 (pdf not found) INN (ACETYLCYSTEINE) ACETYLCYSTEINE (FRESENIUS KABI USA) APPROVAL= AP YEAR= 2012
NDA 203853 (pdf not found) INN (ACETYLCYSTEINE) ACETYLCYSTEINE (ALVOGEN) APPROVAL= AP YEAR= 2012
NDA 204674 (pdf not found) INN (ACETYLCYSTEINE) ACETYLCYSTEINE (ALVOGEN) APPROVAL= AP YEAR= 2014
NDA 203173 (pdf not found) INN (ACETYLCYSTEINE) ACETYLCYSTEINE (RISING) APPROVAL= AP YEAR= 2015
NDA 203624 (pdf not found) INN (ACETYLCYSTEINE) ACETYLCYSTEINE (RISING) APPROVAL= TA YEAR= 2015
NDA 207358 (pdf not found) INN (ACETYLCYSTEINE) ACETYLCYSTEINE (EUGIA PHARMA) APPROVAL= AP YEAR= 2016
NDA 207916 (label) INN (ACETYLCYSTEINE) CETYLEV (ARBOR PHARMS LLC) APPROVAL= AP YEAR= 2016 DISCONTINUED
NDA 091684 (pdf not found) INN (ACETYLCYSTEINE) ACETYLCYSTEINE (SAGENT PHARMS INC) APPROVAL= AP YEAR= 2017
NDA 208166 (pdf not found) INN (ACETYLCYSTEINE) ACETYLCYSTEINE (ZYDUS PHARMS) APPROVAL= AP YEAR= 2018
NDA 204797 (pdf not found) INN (ACETYLCYSTEINE) ACETYLCYSTEINE (EXELA PHARMA) APPROVAL= AP YEAR= 2021 DISCONTINUED
NDA 213693 (pdf not found) INN (ACETYLCYSTEINE) ACETYLCYSTEINE (GLENMARK PHARMS INC) APPROVAL= AP YEAR= 2022
NDA 215620 (pdf not found) INN (ACETYLCYSTEINE) ACETYLCYSTEINE (INDOCO) APPROVAL= AP YEAR= 2022
NDA 217182 (pdf not found) INN (ACETYLCYSTEINE) ACETYLCYSTEINE (ONESOURCE SPECIALTY) APPROVAL= AP YEAR= 2023
NDA 205643 (pdf not found) INN (ACETYLCYSTEINE) ACETYLCYSTEINE (EXELA PHARMA) APPROVAL= AP YEAR= 2023 DISCONTINUED
NDA 215040 (label) INN (ACETYLCYSTEINE LYSINE) LEGUBETI (GALEPHAR) APPROVAL= AP YEAR= 2024 DISCONTINUED
NDA 218397 (pdf not found) INN (ACETYLCYSTEINE) ACETYLCYSTEINE (SOMERSET THERAPS LLC) APPROVAL= AP YEAR= 2024
NDA 214177 (pdf not found) INN (ACETYLCYSTEINE) ACETYLCYSTEINE (CONBA USA) APPROVAL= AP YEAR= 2025
NDA 219194 (pdf not found) INN (ACETYLCYSTEINE) ACETYLCYSTEINE (SOMERSET THERAPS LLC) APPROVAL= AP YEAR= 2025