e-Drug3D

325

QUINETHAZONE

DISCONTINUED

INN
QUINETHAZONE

cas 73-49-4

CLASS

CARDIOVASCULAR
DIURETIC
ANTIHYPERTENSIVE
CARBONIC ANHYDRASE INHIBITOR (PMID23488823)

ROUTE (list)

ORAL

ATC code

C03BA02
C03BB02

PK parameters

Target

TARGET CARBONIC ANHYDRASE

DrugCentral

Solute carrier family 12 member 3 UNIPROT P55017 SLC12A3

Download SDF file

7-chloro-2-ethyl-4-oxo-2,3-dihydro-1H-quinazoline-6-sulfonamide

Formula:
C10H12ClN3O3S

Calculated chemical properties:

MW 289.75
NB_atoms 18
XLogP 0.88
PSA 100.592
NB_HD 4
NB_HA 6
fsp3 0.30
Lipinski(0=no;1=yes) 1

FDA
NDA 013927 (pdf not found) INN (QUINETHAZONE ; RESERPINE) HYDROMOX R (LEDERLE) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 013264 (pdf not found) INN (QUINETHAZONE) HYDROMOX (LEDERLE) APPROVAL= AP YEAR= 1963 NEWMOLECULARENTITY DISCONTINUED