e-Drug3D

TRIMETHADIONE

DISCONTINUED

INN
TRIMETHADIONE

cas 127-48-0

CLASS

NERVOUS SYSTEM
ANTICONVULSANTS
CONTROL OF PETIT MAL SEIZURES
VOLTAGE DEPENDENT T-TYPE CALCIUM CHANNEL INHIBITOR

ROUTE (list)

ORAL

ATC code

N03AC02

PK parameters

Solubility

SOLUBLE IN WATER

Target

TARGET VOLTAGE DEPENDENT CALCIUM CHANNEL (PMID24846538)

Voltage-dependent T-type calcium channel subunit alpha-1G UNIPROT O43497 CACNA1G

Download SDF file

3,5,5-trimethyl-1,3-oxazolidine-2,4-dione

Formula:
C6H9NO3

Calculated chemical properties:

MW 143.14
NB_atoms 10
XLogP 0.37
PSA 48.962
NB_HD 0
NB_HA 4
fsp3 0.67
Lipinski(0=no;1=yes) 1

FDA
NDA 005856 (pdf not found) INN (TRIMETHADIONE) TRIDIONE (ABBVIE) APPROVAL= AP YEAR= 1946 DISCONTINUED