e-Drug3D

31

cas 160970-54-7

CLASS

GENITO
ALPHA-1 ADRENERGIC RECEPTOR ANTAGONIST
PROSTATIC HYPERPLASIA

ROUTE (list)

ORAL

PK parameters

F 32 PERCENT
Tmax 2.6 HOUR
VD 49.5 LITER
Cl 10 LITER / HOUR
PPB 97 PERCENT
t1/2 13.3 HOUR

MW 495.54
NB_atoms 35
XLogP 3.07
PSA 101.515
NB_HD 4
NB_HA 7
fsp3 0.48
Lipinski(0=no;1=yes) 1

FDA
NDA 022206 (label) INN (SILODOSIN) RAPAFLO (ABBVIE) APPROVAL= AP YEAR= 2008 NEWMOLECULARENTITY DISCONTINUED
NDA 204726 (pdf not found) INN (SILODOSIN) SILODOSIN (CHARTWELL RX) APPROVAL= AP YEAR= 2017
NDA 206541 (pdf not found) INN (SILODOSIN) SILODOSIN (LUPIN LTD) APPROVAL= AP YEAR= 2018
NDA 209745 (pdf not found) INN (SILODOSIN) SILODOSIN (AMNEAL PHARMS CO) APPROVAL= AP YEAR= 2018
NDA 210626 (pdf not found) INN (SILODOSIN) SILODOSIN (AUROBINDO PHARMA LTD) APPROVAL= AP YEAR= 2018
NDA 210687 (pdf not found) INN (SILODOSIN) SILODOSIN (MSN) APPROVAL= AP YEAR= 2018
NDA 211060 (pdf not found) INN (SILODOSIN) SILODOSIN (AJANTA PHARMA LTD) APPROVAL= AP YEAR= 2018
NDA 211166 (pdf not found) INN (SILODOSIN) SILODOSIN (MACLEODS PHARMS LTD) APPROVAL= AP YEAR= 2018
NDA 211731 (pdf not found) INN (SILODOSIN) SILODOSIN (ALEMBIC) APPROVAL= AP YEAR= 2019 DISCONTINUED
NDA 204793 (pdf not found) INN (SILODOSIN) SILODOSIN (HETERO LABS LTD V) APPROVAL= AP YEAR= 2020
NDA 209029 (pdf not found) INN (SILODOSIN) SILODOSIN (PRINSTON INC) APPROVAL= AP YEAR= 2022
NDA 213230 (pdf not found) INN (SILODOSIN) SILODOSIN (CREEKWOOD PHARMS) APPROVAL= AP YEAR= 2022
NDA 204816 (pdf not found) INN (SILODOSIN) SILODOSIN (ZYDUS PHARMS) APPROVAL= AP YEAR= 2022 DISCONTINUED
NDA 210396 (pdf not found) INN (SILODOSIN) SILODOSIN (TORRENT) APPROVAL= AP YEAR= 2025 DISCONTINUED