e-Drug3D

299

CHLORPROTHIXENE

DISCONTINUED

INN
CHLORPROTHIXENE

cas 113-59-7

CLASS

NERVOUS SYSTEM
ANTIPSYCHOTIC
DOPAMINE D2 ANTAGONISTS

ROUTE (list)

ORAL INJECTION

ATC code

N05AF03

PK parameters

F 17 PERCENT (PMID10525070)
Tmax 4 HOUR
VD 1035 LITER
Cl 52 LITER / HOUR
t1/2 25.8 HOUR

Target

TARGET D(2) DOPAMINE RECEPTOR

DrugCentral

D(2) dopamine receptor UNIPROT P14416 DRD2

Download SDF file

3-(2-chlorothioxanthen-9-ylidene)-N,N-dimethylpropan-1-amine

Formula:
C18H18ClNS

Calculated chemical properties:

MW 315.85
NB_atoms 21
XLogP 5.19
PSA 5.838
NB_HD 0
NB_HA 1
fsp3 0.22
Lipinski(0=no;1=yes) 0

FDA
NDA 012486 (pdf not found) INN (CHLORPROTHIXENE) TARACTAN (ROCHE) APPROVAL= AP YEAR= 1962 DISCONTINUED
NDA 012487 (pdf not found) INN (CHLORPROTHIXENE) TARACTAN (ROCHE) APPROVAL= AP YEAR= 1962 DISCONTINUED
NDA 016149 (pdf not found) INN (CHLORPROTHIXENE) TARACTAN (ROCHE) APPROVAL= AP YEAR= 1967 DISCONTINUED