e-Drug3D
296
ATROPINE
INN
ATROPINE
cas 51-55-8
CLASS
METABOLISM
ALKALOID
ANTICHOLINERGIC
MUSCARINIC ANTAGONISTS
MYDRIATICS
PARASYMPATHOLYTICS
ACTIVITY IS DUE ALMOST ENTIRELY TO THE LEVO ISOMER
TREATMENT OF POISONING BY ORGANOPHOSPHOROUS NERVE AGENTS
ROUTE (list)
ORAL INTRAMUSCULAR INJECTION INHALATION INTRAVENOUS OPHTHALMIC SUBCUTANEOUS INTRAOSSEOUS ENDOTRACHEAL
PK parameters
Tmax 0.05 HOUR
VD 214.5 LITER (65 KILOGRAM)
Cl 29.6 LITER / HOUR (65 KILOGRAM)
PPB 18 PERCENT
t1/2 3 HOUR
Solubility
HIGHLY SOLUBLE IN WATER
TARGET MUSCARINIC ACETYLCHOLINE RECEPTOR
PDB
1TH6 (CRYSTAL STRUCTURE OF PHOSPHOLIPASE A2 IN COMPLEX WITH ATROPINE AT 1.23A RESOLUTION)
Ligand code = OIN (link to the list of PDB complexes)
Download experimental 3D coordinates of OIN with added hydrogens
Muscarinic acetylcholine receptor M1 UNIPROT P11229 CHRM1
Muscarinic acetylcholine receptor M2 UNIPROT P08172 CHRM2
Formula:
C17H23NO3
Calculated chemical properties:
MW 289.36
NB_atoms 21
XLogP 1.93
PSA 42.403
NB_HD 1
NB_HA 4
fsp3 0.59
Lipinski(0=no;1=yes) 1
NB_atoms 21
XLogP 1.93
PSA 42.403
NB_HD 1
NB_HA 4
fsp3 0.59
Lipinski(0=no;1=yes) 1
FDA
NDA 085121 (pdf not found) INN (ATROPINE SULFATE ; MEPERIDINE HYDROCHLORIDE) MEPERIDINE AND ATROPINE SULFATE (WYETH AYERST) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 085211 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) LOW-QUEL (HALSEY) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 085737 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) COLONAID (MEDPOINTE PHARM HLC) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 085746 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) LOMANATE (ALPHARMA US PHARMS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 086057 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (ROXANE) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 086798 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (HEATHER) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 087847 (pdf not found) INN (ATROPINE SULFATE ; MEPERIDINE HYDROCHLORIDE) ATROPINE AND DEMEROL (ABBVIE) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 087848 (pdf not found) INN (ATROPINE SULFATE ; MEPERIDINE HYDROCHLORIDE) ATROPINE AND DEMEROL (ABBVIE) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 087853 (pdf not found) INN (ATROPINE SULFATE ; MEPERIDINE HYDROCHLORIDE) ATROPINE AND DEMEROL (ABBVIE) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 087934 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (ASCOT) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 012462 (label) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) LOMOTIL (PFIZER) APPROVAL= AP YEAR= 1960
NDA 012699 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) LOMOTIL (GD SEARLE LLC) APPROVAL= AP YEAR= 1961 DISCONTINUED
NDA 017106 (label) INN (ATROPINE) ATROPEN (MMT) APPROVAL= AP YEAR= 1973 DISCONTINUED
NDA 085035 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (R AND S PHARMA) APPROVAL= AP YEAR= 1977 DISCONTINUED
NDA 085266 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DI-ATRO (MD PHARM) APPROVAL= AP YEAR= 1977 DISCONTINUED
NDA 085311 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) LONOX (FOSUN PHARMA) APPROVAL= AP YEAR= 1977 DISCONTINUED
NDA 085506 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (SUN PHARM INDUSTRIES) APPROVAL= AP YEAR= 1977 DISCONTINUED
NDA 085762 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (PHARMOBEDIENT) APPROVAL= AP YEAR= 1977 DISCONTINUED
NDA 017744 (label) INN (ATROPINE SULFATE ; DIFENOXIN HYDROCHLORIDE) MOTOFEN HALF-STRENGTH (LEGACY PHARMA) APPROVAL= AP YEAR= 1978
NDA 085372 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (LANNETT) APPROVAL= AP YEAR= 1978
NDA 085509 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (INWOOD LABS) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 085659 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (KV PHARM) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 085735 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) COLONAID (MEDPOINTE PHARM HLC) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 085766 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (PVT FORM) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 085876 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (WATSON LABS) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 086727 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (ANI PHARMS) APPROVAL= AP YEAR= 1979 DISCONTINUED
NDA 086173 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (FOSUN PHARMA) APPROVAL= AP YEAR= 1981 DISCONTINUED
NDA 086440 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE W/ ATROPINE SULFATE (SCHERER RP) APPROVAL= AP YEAR= 1981 DISCONTINUED
NDA 087131 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (PARKE DAVIS) APPROVAL= AP YEAR= 1981 DISCONTINUED
NDA 086950 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (LEDERLE) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 087708 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (HIKMA) APPROVAL= AP YEAR= 1982
NDA 087765 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (HIKMA) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 087842 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (USL PHARMA) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 088009 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) LO-TROL (VANGARD) APPROVAL= AP YEAR= 1983 DISCONTINUED
NDA 088962 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) LOGEN (SUPERPHARM) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 071295 (pdf not found) INN (ATROPINE) ATROPINE (ABBVIE) APPROVAL= AP YEAR= 1987 DISCONTINUED
NDA 020056 (pdf not found) INN (ATROPINE SULFATE) ATROPINE SULFATE (US ARMY) APPROVAL= AP YEAR= 1990 DISCONTINUED
NDA 019677 (label) INN (ATROPINE SULFATE ; EDROPHONIUM CHLORIDE) ENLON-PLUS (MYLAN INSTITUTIONAL) APPROVAL= AP YEAR= 1991 DISCONTINUED
NDA 019678 (label) INN (ATROPINE SULFATE ; EDROPHONIUM CHLORIDE) ENLON-PLUS (MYLAN) APPROVAL= AP YEAR= 1991 DISCONTINUED
NDA 087195 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (VALEANT PHARM INTL) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 040357 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (STRIDES PHARMA) APPROVAL= AP YEAR= 2000 DISCONTINUED
NDA 040395 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (ABLE) APPROVAL= AP YEAR= 2000 DISCONTINUED
NDA 021146 (label) INN (ATROPINE SULFATE) ATROPINE SULFATE (HOSPIRA) APPROVAL= AP YEAR= 2001
NDA 021175 (label) INN (ATROPINE ; PRALIDOXIME CHLORIDE) ATNAA (US ARMY) APPROVAL= AP YEAR= 2002 DISCONTINUED
NDA 021983 (label) INN (ATROPINE ; PRALIDOXIME CHLORIDE) DUODOTE (MMT) APPROVAL= AP YEAR= 2006
NDA 206289 (label) INN (ATROPINE SULFATE) ATROPINE SULFATE (RISING) APPROVAL= AP YEAR= 2014
NDA 208151 (label) INN (ATROPINE SULFATE) ISOPTO ATROPINE (ALCON LABS INC) APPROVAL= AP YEAR= 2016
NDA 209260 (label) INN (ATROPINE SULFATE) ATROPINE SULFATE (FRESENIUS KABI USA) APPROVAL= AP YEAR= 2018
NDA 210571 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (UPSHER SMITH LABS) APPROVAL= AP YEAR= 2018 DISCONTINUED
NDA 210819 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (UNICHEM) APPROVAL= AP YEAR= 2018
NDA 212319 (label) INN (ATROPINE) ATROPINE AUTOINJECTOR (RAFA LABS LTD) APPROVAL= AP YEAR= 2018 DISCONTINUED
NDA 210789 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (DR REDDYS LABS SA) APPROVAL= AP YEAR= 2020 DISCONTINUED
NDA 213413 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (LEADING) APPROVAL= AP YEAR= 2020
NDA 207128 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (CHARTWELL RX) APPROVAL= AP YEAR= 2020
NDA 212461 (pdf not found) INN (ATROPINE SULFATE) ATROPINE SULFATE (INTL MEDICATION SYS) APPROVAL= AP YEAR= 2020
NDA 213335 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (SPECGX LLC) APPROVAL= AP YEAR= 2020
NDA 214652 (label) INN (ATROPINE SULFATE) ATROPINE SULFATE (ACCORD HLTHCARE) APPROVAL= AP YEAR= 2020
NDA 211362 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (WINDER LABS LLC) APPROVAL= AP YEAR= 2021
NDA 213424 (pdf not found) INN (ATROPINE SULFATE) ATROPINE SULFATE (ACCORD HLTHCARE) APPROVAL= AP YEAR= 2021
NDA 212868 (pdf not found) INN (ATROPINE SULFATE) ATROPINE SULFATE (ACCORD HLTHCARE) APPROVAL= AP YEAR= 2021
NDA 213561 (pdf not found) INN (ATROPINE SULFATE) ATROPINE SULFATE (HIKMA) APPROVAL= AP YEAR= 2021
NDA 215624 (pdf not found) INN (ATROPINE SULFATE) ATROPINE SULFATE (APOTEX) APPROVAL= AP YEAR= 2021
NDA 214752 (pdf not found) INN (ATROPINE SULFATE) ATROPINE SULFATE (AMNEAL) APPROVAL= AP YEAR= 2022
NDA 213581 (label) INN (ATROPINE SULFATE) ATROPINE SULFATE (BAUSCH AND LOMB INC) APPROVAL= AP YEAR= 2022
NDA 215342 (pdf not found) INN (ATROPINE SULFATE) ATROPINE SULFATE (AMNEAL) APPROVAL= AP YEAR= 2022
NDA 216120 (pdf not found) INN (ATROPINE SULFATE) ATROPINE SULFATE (AM REGENT) APPROVAL= AP YEAR= 2022
NDA 214970 (pdf not found) INN (ATROPINE SULFATE) ATROPINE SULFATE (MEDEFIL INC) APPROVAL= AP YEAR= 2022
NDA 217791 (pdf not found) INN (ATROPINE SULFATE) ATROPINE SULFATE (SOMERSET) APPROVAL= AP YEAR= 2024
NDA 218148 (pdf not found) INN (ATROPINE SULFATE) ATROPINE SULFATE (MANKIND PHARMA) APPROVAL= AP YEAR= 2024
NDA 215005 (pdf not found) INN (ATROPINE SULFATE) ATROPINE SULFATE (SOMERSET THERAPS LLC) APPROVAL= AP YEAR= 2024
NDA 215618 (pdf not found) INN (ATROPINE SULFATE) ATROPINE SULFATE (SOMERSET THERAPS LLC) APPROVAL= AP YEAR= 2024
NDA 215969 (pdf not found) INN (ATROPINE SULFATE) ATROPINE SULFATE (SOMERSET THERAPS LLC) APPROVAL= AP YEAR= 2024
NDA 085121 (pdf not found) INN (ATROPINE SULFATE ; MEPERIDINE HYDROCHLORIDE) MEPERIDINE AND ATROPINE SULFATE (WYETH AYERST) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 085211 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) LOW-QUEL (HALSEY) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 085737 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) COLONAID (MEDPOINTE PHARM HLC) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 085746 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) LOMANATE (ALPHARMA US PHARMS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 086057 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (ROXANE) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 086798 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (HEATHER) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 087847 (pdf not found) INN (ATROPINE SULFATE ; MEPERIDINE HYDROCHLORIDE) ATROPINE AND DEMEROL (ABBVIE) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 087848 (pdf not found) INN (ATROPINE SULFATE ; MEPERIDINE HYDROCHLORIDE) ATROPINE AND DEMEROL (ABBVIE) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 087853 (pdf not found) INN (ATROPINE SULFATE ; MEPERIDINE HYDROCHLORIDE) ATROPINE AND DEMEROL (ABBVIE) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 087934 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (ASCOT) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 012462 (label) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) LOMOTIL (PFIZER) APPROVAL= AP YEAR= 1960
NDA 012699 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) LOMOTIL (GD SEARLE LLC) APPROVAL= AP YEAR= 1961 DISCONTINUED
NDA 017106 (label) INN (ATROPINE) ATROPEN (MMT) APPROVAL= AP YEAR= 1973 DISCONTINUED
NDA 085035 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (R AND S PHARMA) APPROVAL= AP YEAR= 1977 DISCONTINUED
NDA 085266 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DI-ATRO (MD PHARM) APPROVAL= AP YEAR= 1977 DISCONTINUED
NDA 085311 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) LONOX (FOSUN PHARMA) APPROVAL= AP YEAR= 1977 DISCONTINUED
NDA 085506 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (SUN PHARM INDUSTRIES) APPROVAL= AP YEAR= 1977 DISCONTINUED
NDA 085762 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (PHARMOBEDIENT) APPROVAL= AP YEAR= 1977 DISCONTINUED
NDA 017744 (label) INN (ATROPINE SULFATE ; DIFENOXIN HYDROCHLORIDE) MOTOFEN HALF-STRENGTH (LEGACY PHARMA) APPROVAL= AP YEAR= 1978
NDA 085372 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (LANNETT) APPROVAL= AP YEAR= 1978
NDA 085509 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (INWOOD LABS) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 085659 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (KV PHARM) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 085735 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) COLONAID (MEDPOINTE PHARM HLC) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 085766 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (PVT FORM) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 085876 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (WATSON LABS) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 086727 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (ANI PHARMS) APPROVAL= AP YEAR= 1979 DISCONTINUED
NDA 086173 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (FOSUN PHARMA) APPROVAL= AP YEAR= 1981 DISCONTINUED
NDA 086440 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE W/ ATROPINE SULFATE (SCHERER RP) APPROVAL= AP YEAR= 1981 DISCONTINUED
NDA 087131 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (PARKE DAVIS) APPROVAL= AP YEAR= 1981 DISCONTINUED
NDA 086950 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (LEDERLE) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 087708 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (HIKMA) APPROVAL= AP YEAR= 1982
NDA 087765 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (HIKMA) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 087842 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (USL PHARMA) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 088009 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) LO-TROL (VANGARD) APPROVAL= AP YEAR= 1983 DISCONTINUED
NDA 088962 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) LOGEN (SUPERPHARM) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 071295 (pdf not found) INN (ATROPINE) ATROPINE (ABBVIE) APPROVAL= AP YEAR= 1987 DISCONTINUED
NDA 020056 (pdf not found) INN (ATROPINE SULFATE) ATROPINE SULFATE (US ARMY) APPROVAL= AP YEAR= 1990 DISCONTINUED
NDA 019677 (label) INN (ATROPINE SULFATE ; EDROPHONIUM CHLORIDE) ENLON-PLUS (MYLAN INSTITUTIONAL) APPROVAL= AP YEAR= 1991 DISCONTINUED
NDA 019678 (label) INN (ATROPINE SULFATE ; EDROPHONIUM CHLORIDE) ENLON-PLUS (MYLAN) APPROVAL= AP YEAR= 1991 DISCONTINUED
NDA 087195 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (VALEANT PHARM INTL) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 040357 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (STRIDES PHARMA) APPROVAL= AP YEAR= 2000 DISCONTINUED
NDA 040395 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (ABLE) APPROVAL= AP YEAR= 2000 DISCONTINUED
NDA 021146 (label) INN (ATROPINE SULFATE) ATROPINE SULFATE (HOSPIRA) APPROVAL= AP YEAR= 2001
NDA 021175 (label) INN (ATROPINE ; PRALIDOXIME CHLORIDE) ATNAA (US ARMY) APPROVAL= AP YEAR= 2002 DISCONTINUED
NDA 021983 (label) INN (ATROPINE ; PRALIDOXIME CHLORIDE) DUODOTE (MMT) APPROVAL= AP YEAR= 2006
NDA 206289 (label) INN (ATROPINE SULFATE) ATROPINE SULFATE (RISING) APPROVAL= AP YEAR= 2014
NDA 208151 (label) INN (ATROPINE SULFATE) ISOPTO ATROPINE (ALCON LABS INC) APPROVAL= AP YEAR= 2016
NDA 209260 (label) INN (ATROPINE SULFATE) ATROPINE SULFATE (FRESENIUS KABI USA) APPROVAL= AP YEAR= 2018
NDA 210571 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (UPSHER SMITH LABS) APPROVAL= AP YEAR= 2018 DISCONTINUED
NDA 210819 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (UNICHEM) APPROVAL= AP YEAR= 2018
NDA 212319 (label) INN (ATROPINE) ATROPINE AUTOINJECTOR (RAFA LABS LTD) APPROVAL= AP YEAR= 2018 DISCONTINUED
NDA 210789 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (DR REDDYS LABS SA) APPROVAL= AP YEAR= 2020 DISCONTINUED
NDA 213413 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (LEADING) APPROVAL= AP YEAR= 2020
NDA 207128 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (CHARTWELL RX) APPROVAL= AP YEAR= 2020
NDA 212461 (pdf not found) INN (ATROPINE SULFATE) ATROPINE SULFATE (INTL MEDICATION SYS) APPROVAL= AP YEAR= 2020
NDA 213335 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (SPECGX LLC) APPROVAL= AP YEAR= 2020
NDA 214652 (label) INN (ATROPINE SULFATE) ATROPINE SULFATE (ACCORD HLTHCARE) APPROVAL= AP YEAR= 2020
NDA 211362 (pdf not found) INN (ATROPINE SULFATE ; DIPHENOXYLATE HYDROCHLORIDE) DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (WINDER LABS LLC) APPROVAL= AP YEAR= 2021
NDA 213424 (pdf not found) INN (ATROPINE SULFATE) ATROPINE SULFATE (ACCORD HLTHCARE) APPROVAL= AP YEAR= 2021
NDA 212868 (pdf not found) INN (ATROPINE SULFATE) ATROPINE SULFATE (ACCORD HLTHCARE) APPROVAL= AP YEAR= 2021
NDA 213561 (pdf not found) INN (ATROPINE SULFATE) ATROPINE SULFATE (HIKMA) APPROVAL= AP YEAR= 2021
NDA 215624 (pdf not found) INN (ATROPINE SULFATE) ATROPINE SULFATE (APOTEX) APPROVAL= AP YEAR= 2021
NDA 214752 (pdf not found) INN (ATROPINE SULFATE) ATROPINE SULFATE (AMNEAL) APPROVAL= AP YEAR= 2022
NDA 213581 (label) INN (ATROPINE SULFATE) ATROPINE SULFATE (BAUSCH AND LOMB INC) APPROVAL= AP YEAR= 2022
NDA 215342 (pdf not found) INN (ATROPINE SULFATE) ATROPINE SULFATE (AMNEAL) APPROVAL= AP YEAR= 2022
NDA 216120 (pdf not found) INN (ATROPINE SULFATE) ATROPINE SULFATE (AM REGENT) APPROVAL= AP YEAR= 2022
NDA 214970 (pdf not found) INN (ATROPINE SULFATE) ATROPINE SULFATE (MEDEFIL INC) APPROVAL= AP YEAR= 2022
NDA 217791 (pdf not found) INN (ATROPINE SULFATE) ATROPINE SULFATE (SOMERSET) APPROVAL= AP YEAR= 2024
NDA 218148 (pdf not found) INN (ATROPINE SULFATE) ATROPINE SULFATE (MANKIND PHARMA) APPROVAL= AP YEAR= 2024
NDA 215005 (pdf not found) INN (ATROPINE SULFATE) ATROPINE SULFATE (SOMERSET THERAPS LLC) APPROVAL= AP YEAR= 2024
NDA 215618 (pdf not found) INN (ATROPINE SULFATE) ATROPINE SULFATE (SOMERSET THERAPS LLC) APPROVAL= AP YEAR= 2024
NDA 215969 (pdf not found) INN (ATROPINE SULFATE) ATROPINE SULFATE (SOMERSET THERAPS LLC) APPROVAL= AP YEAR= 2024