e-Drug3D
288
TRANYLCYPROMINE
INN
TRANYLCYPROMINE
cas 155-09-9
CLASS
NERVOUS SYSTEM
ANTIDEPRESSANT
ANTI-ANXIETY AGENTS
MONOAMINE OXIDASE (MAO) INHIBITORS
ROUTE (list)
ORAL
ATC code
N06AF04
PK parameters
Tmax 1 HOUR (PMID3757407)
Cl 63.4 LITER / HOUR
t1/2 1.58 HOUR
TARGET MONOAMINE OXIDASE MAO
PDB
3MDR (TRANYLCYPROMINE COMPLEX OF CYTOCHROME P450 46A1)
Ligand code = GJZ (link to the list of PDB complexes)
Download experimental 3D coordinates of GJZ with added hydrogens
Amine oxidase flavin-containing B UNIPROT P27338 MAOB
Formula:
C9H11N
Calculated chemical properties:
MW 133.19
NB_atoms 10
XLogP 1.50
PSA 25.536
NB_HD 2
NB_HA 1
fsp3 0.33
Lipinski(0=no;1=yes) 1
NB_atoms 10
XLogP 1.50
PSA 25.536
NB_HD 2
NB_HA 1
fsp3 0.33
Lipinski(0=no;1=yes) 1
FDA
NDA 012342 (pdf not found) INN (TRANYLCYPROMINE SULFATE) PARNATE (ADVANZ PHARMA) APPROVAL= AP YEAR= 1961
NDA 040640 (pdf not found) INN (TRANYLCYPROMINE SULFATE) TRANYLCYPROMINE SULFATE (STRIDES PHARMA) APPROVAL= AP YEAR= 2006
NDA 206856 (pdf not found) INN (TRANYLCYPROMINE SULFATE) TRANYLCYPROMINE SULFATE (NOVITIUM PHARMA) APPROVAL= AP YEAR= 2018
NDA 213503 (pdf not found) INN (TRANYLCYPROMINE SULFATE) TRANYLCYPROMINE SULFATE (CROSSMEDIKA SA) APPROVAL= AP YEAR= 2022
NDA 012342 (pdf not found) INN (TRANYLCYPROMINE SULFATE) PARNATE (ADVANZ PHARMA) APPROVAL= AP YEAR= 1961
NDA 040640 (pdf not found) INN (TRANYLCYPROMINE SULFATE) TRANYLCYPROMINE SULFATE (STRIDES PHARMA) APPROVAL= AP YEAR= 2006
NDA 206856 (pdf not found) INN (TRANYLCYPROMINE SULFATE) TRANYLCYPROMINE SULFATE (NOVITIUM PHARMA) APPROVAL= AP YEAR= 2018
NDA 213503 (pdf not found) INN (TRANYLCYPROMINE SULFATE) TRANYLCYPROMINE SULFATE (CROSSMEDIKA SA) APPROVAL= AP YEAR= 2022