e-Drug3D
283
TRICHLORMETHIAZIDE
DISCONTINUED
INN
TRICHLORMETHIAZIDE
cas 133-67-5
CLASS
CARDIOVASCULAR
DIURETIC
ANTIHYPERTENSIVE
SODIUM CHLORIDE SYMPORTER INHIBITORS
ROUTE (list)
ORAL
PK parameters
TARGET SODIUM CHLORIDE SYMPORTER
Solute carrier family 12 member 3 UNIPROT P55017 SLC12A3
Formula:
C8H8Cl3N3O4S2
Calculated chemical properties:
MW 380.66
NB_atoms 20
XLogP 0.82
PSA 118.716
NB_HD 4
NB_HA 7
fsp3 0.25
Lipinski(0=no;1=yes) 1
NB_atoms 20
XLogP 0.82
PSA 118.716
NB_HD 4
NB_HA 7
fsp3 0.25
Lipinski(0=no;1=yes) 1
FDA
NDA 012972 (pdf not found) INN (RESERPINE ; TRICHLORMETHIAZIDE) METATENSIN #2 (SANOFI AVENTIS US) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 083462 (pdf not found) INN (TRICHLORMETHIAZIDE) TRICHLORMETHIAZIDE (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 083967 (pdf not found) INN (TRICHLORMETHIAZIDE) TRICHLORMETHIAZIDE (IMPAX LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 085962 (pdf not found) INN (TRICHLORMETHIAZIDE) TRICHLORMETHIAZIDE (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 086259 (pdf not found) INN (TRICHLORMETHIAZIDE) TRICHLORMAS (MAST MM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 012265 (pdf not found) INN (TRICHLORMETHIAZIDE) NAQUA (SCHERING) APPROVAL= AP YEAR= 1960 NEWMOLECULARENTITY DISCONTINUED
NDA 083855 (pdf not found) INN (TRICHLORMETHIAZIDE) TRICHLORMETHIAZIDE (WATSON LABS) APPROVAL= AP YEAR= 1977 DISCONTINUED
NDA 085568 (pdf not found) INN (TRICHLORMETHIAZIDE) TRICHLORMETHIAZIDE (CHARTWELL RX) APPROVAL= AP YEAR= 1977 DISCONTINUED
NDA 085630 (pdf not found) INN (TRICHLORMETHIAZIDE) TRICHLOREX (LANNETT) APPROVAL= AP YEAR= 1977 DISCONTINUED
NDA 083847 (pdf not found) INN (TRICHLORMETHIAZIDE) TRICHLORMETHIAZIDE (WATSON LABS) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 086458 (pdf not found) INN (TRICHLORMETHIAZIDE) TRICHLORMETHIAZIDE (WATSON LABS) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 083436 (pdf not found) INN (TRICHLORMETHIAZIDE) TRICHLOREX (LANNETT) APPROVAL= AP YEAR= 1980 DISCONTINUED
NDA 087005 (pdf not found) INN (TRICHLORMETHIAZIDE) TRICHLORMETHIAZIDE (PAR PHARM) APPROVAL= AP YEAR= 1981 DISCONTINUED
NDA 087007 (pdf not found) INN (TRICHLORMETHIAZIDE) TRICHLORMETHIAZIDE (PAR PHARM) APPROVAL= AP YEAR= 1981 DISCONTINUED
NDA 086171 (pdf not found) INN (TRICHLORMETHIAZIDE) TRICHLORMETHIAZIDE (SANDOZ) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 085248 (pdf not found) INN (RESERPINE ; TRICHLORMETHIAZIDE) TRICHLORMETHIAZIDE W/ RESERPINE (WATSON LABS) APPROVAL= AP YEAR= 1983 DISCONTINUED
NDA 012594 (pdf not found) INN (TRICHLORMETHIAZIDE) METAHYDRIN (SANOFI AVENTIS US) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 012972 (pdf not found) INN (RESERPINE ; TRICHLORMETHIAZIDE) METATENSIN #2 (SANOFI AVENTIS US) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 083462 (pdf not found) INN (TRICHLORMETHIAZIDE) TRICHLORMETHIAZIDE (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 083967 (pdf not found) INN (TRICHLORMETHIAZIDE) TRICHLORMETHIAZIDE (IMPAX LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 085962 (pdf not found) INN (TRICHLORMETHIAZIDE) TRICHLORMETHIAZIDE (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 086259 (pdf not found) INN (TRICHLORMETHIAZIDE) TRICHLORMAS (MAST MM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 012265 (pdf not found) INN (TRICHLORMETHIAZIDE) NAQUA (SCHERING) APPROVAL= AP YEAR= 1960 NEWMOLECULARENTITY DISCONTINUED
NDA 083855 (pdf not found) INN (TRICHLORMETHIAZIDE) TRICHLORMETHIAZIDE (WATSON LABS) APPROVAL= AP YEAR= 1977 DISCONTINUED
NDA 085568 (pdf not found) INN (TRICHLORMETHIAZIDE) TRICHLORMETHIAZIDE (CHARTWELL RX) APPROVAL= AP YEAR= 1977 DISCONTINUED
NDA 085630 (pdf not found) INN (TRICHLORMETHIAZIDE) TRICHLOREX (LANNETT) APPROVAL= AP YEAR= 1977 DISCONTINUED
NDA 083847 (pdf not found) INN (TRICHLORMETHIAZIDE) TRICHLORMETHIAZIDE (WATSON LABS) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 086458 (pdf not found) INN (TRICHLORMETHIAZIDE) TRICHLORMETHIAZIDE (WATSON LABS) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 083436 (pdf not found) INN (TRICHLORMETHIAZIDE) TRICHLOREX (LANNETT) APPROVAL= AP YEAR= 1980 DISCONTINUED
NDA 087005 (pdf not found) INN (TRICHLORMETHIAZIDE) TRICHLORMETHIAZIDE (PAR PHARM) APPROVAL= AP YEAR= 1981 DISCONTINUED
NDA 087007 (pdf not found) INN (TRICHLORMETHIAZIDE) TRICHLORMETHIAZIDE (PAR PHARM) APPROVAL= AP YEAR= 1981 DISCONTINUED
NDA 086171 (pdf not found) INN (TRICHLORMETHIAZIDE) TRICHLORMETHIAZIDE (SANDOZ) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 085248 (pdf not found) INN (RESERPINE ; TRICHLORMETHIAZIDE) TRICHLORMETHIAZIDE W/ RESERPINE (WATSON LABS) APPROVAL= AP YEAR= 1983 DISCONTINUED
NDA 012594 (pdf not found) INN (TRICHLORMETHIAZIDE) METAHYDRIN (SANOFI AVENTIS US) APPROVAL= AP YEAR= 1988 DISCONTINUED