e-Drug3D

279

BENDROFLUMETHIAZIDE

DISCONTINUED

INN
BENDROFLUMETHIAZIDE

cas 73-48-3

CLASS

CARDIOVASCULAR
DIURETIC
ANTIHYPERTENSIVE
SODIUM CHLORIDE SYMPORTER INHIBITORS

ROUTE (list)

ORAL

ATC code

C03AA01
C03AB01
C03EA13

PK parameters

PPB 90 PERCENT

Solubility

INSOLUBLE IN WATER

Target

TARGET SODIUM CHLORIDE SYMPORTER
CARBONIC ANHYDRASE

DrugCentral

Solute carrier family 12 member 3 UNIPROT P55017 SLC12A3

Download SDF file

1,1-dioxo-3-(phenylmethyl)-6-(trifluoromethyl)-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide

Formula:
C15H14F3N3O4S2

Calculated chemical properties:

MW 421.43
NB_atoms 27
XLogP 1.63
PSA 113.694
NB_HD 4
NB_HA 7
fsp3 0.20
Lipinski(0=no;1=yes) 1

FDA
NDA 012164 (pdf not found) INN (BENDROFLUMETHIAZIDE) NATURETIN-2.5 (APOTHECON) APPROVAL= AP YEAR= 1959 DISCONTINUED
NDA 018647 (pdf not found) INN (BENDROFLUMETHIAZIDE ; NADOLOL) CORZIDE (KING PHARMS LLC) APPROVAL= AP YEAR= 1983 DISCONTINUED
NDA 077833 (pdf not found) INN (BENDROFLUMETHIAZIDE ; NADOLOL) NADOLOL AND BENDROFLUMETHIAZIDE (IMPAX LABS) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 078688 (pdf not found) INN (BENDROFLUMETHIAZIDE ; NADOLOL) NADOLOL AND BENDROFLUMETHIAZIDE (NATCO PHARMA) APPROVAL= AP YEAR= 2008 DISCONTINUED