e-Drug3D

277

cas 50-18-0

CLASS

ANTINEOPLASTIC
ALKYLATING

ROUTE (list)

ORAL INJECTION INTRAVENOUS

PK parameters

Tmax 1 HOUR
VD 40 LITER
Cl 4.8 LITER / HOUR
PPB 20 PERCENT
t1/2 7.5 HOUR

MW 261.08
NB_atoms 14
XLogP 1.88
PSA 47.873
NB_HD 1
NB_HA 4
fsp3 1.00
Lipinski(0=no;1=yes) 1

FDA
NDA 012141 (label) INN (CYCLOPHOSPHAMIDE) CYTOXAN (BAXTER HLTHCARE) APPROVAL= AP YEAR= 1959
NDA 012142 (label) INN (CYCLOPHOSPHAMIDE) CYTOXAN (BAXTER HLTHCARE) APPROVAL= AP YEAR= 1959 DISCONTINUED
NDA 087442 (pdf not found) INN (CYCLOPHOSPHAMIDE) NEOSAR (BEDFORD) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 088371 (pdf not found) INN (CYCLOPHOSPHAMIDE) CYCLOPHOSPHAMIDE (BAXTER HLTHCARE) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 088372 (pdf not found) INN (CYCLOPHOSPHAMIDE) CYCLOPHOSPHAMIDE (BAXTER HLTHCARE) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 088373 (pdf not found) INN (CYCLOPHOSPHAMIDE) CYCLOPHOSPHAMIDE (BAXTER HLTHCARE) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 088374 (pdf not found) INN (CYCLOPHOSPHAMIDE) CYCLOPHOSPHAMIDE (BAXTER HLTHCARE) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 040015 (pdf not found) INN (CYCLOPHOSPHAMIDE) NEOSAR (TEVA PARENTERAL) APPROVAL= AP YEAR= 1993 DISCONTINUED
NDA 040032 (pdf not found) INN (CYCLOPHOSPHAMIDE) CYCLOPHOSPHAMIDE (ROXANE) APPROVAL= AP YEAR= 1999 DISCONTINUED
NDA 040745 (label) INN (CYCLOPHOSPHAMIDE) CYCLOPHOSPHAMIDE (BAXTER HLTHCARE) APPROVAL= AP YEAR= 2008
NDA 203856 (label) INN (CYCLOPHOSPHAMIDE) CYCLOPHOSPHAMIDE (HIKMA) APPROVAL= AP YEAR= 2013
NDA 204555 (pdf not found) INN (CYCLOPHOSPHAMIDE) CYCLOPHOSPHAMIDE (HENGRUI PHARMA) APPROVAL= AP YEAR= 2014
NDA 207014 (pdf not found) INN (CYCLOPHOSPHAMIDE) CYCLOPHOSPHAMIDE (ANI PHARMS) APPROVAL= AP YEAR= 2018 DISCONTINUED
NDA 209872 (pdf not found) INN (CYCLOPHOSPHAMIDE) CYCLOPHOSPHAMIDE (KANCHAN HLTHCARE) APPROVAL= AP YEAR= 2018
NDA 210046 (pdf not found) INN (CYCLOPHOSPHAMIDE) CYCLOPHOSPHAMIDE (AMNEAL) APPROVAL= AP YEAR= 2018
NDA 211608 (pdf not found) INN (CYCLOPHOSPHAMIDE) CYCLOPHOSPHAMIDE (CIPLA) APPROVAL= AP YEAR= 2019
NDA 212501 (label) INN (CYCLOPHOSPHAMIDE) CYCLOPHOSPHAMIDE (DR REDDYS) APPROVAL= AP YEAR= 2020
NDA 210735 (label) INN (CYCLOPHOSPHAMIDE) CYCLOPHOSPHAMIDE (EUGIA PHARMA SPECLTS) APPROVAL= AP YEAR= 2021
NDA 211757 (pdf not found) INN (CYCLOPHOSPHAMIDE) CYCLOPHOSPHAMIDE (XGEN PHARMS) APPROVAL= AP YEAR= 2022
NDA 215892 (pdf not found) INN (CYCLOPHOSPHAMIDE) CYCLOPHOSPHAMIDE (ALEMBIC) APPROVAL= AP YEAR= 2022
NDA 210852 (label) INN (CYCLOPHOSPHAMIDE) CYCLOPHOSPHAMIDE (AVYXA HOLDINGS) APPROVAL= AP YEAR= 2023
NDA 211552 (pdf not found) INN (CYCLOPHOSPHAMIDE) CYCLOPHOSPHAMIDE (ZYDUS LIFESCIENCES) APPROVAL= AP YEAR= 2023
NDA 214529 (pdf not found) INN (CYCLOPHOSPHAMIDE) CYCLOPHOSPHAMIDE (SAGENT PHARMS INC) APPROVAL= AP YEAR= 2023
NDA 215089 (pdf not found) INN (CYCLOPHOSPHAMIDE) CYCLOPHOSPHAMIDE (SUNNY) APPROVAL= AP YEAR= 2023
NDA 216958 (pdf not found) INN (CYCLOPHOSPHAMIDE) CYCLOPHOSPHAMIDE (HIKMA) APPROVAL= AP YEAR= 2023
NDA 217150 (label) INN (CYCLOPHOSPHAMIDE) CYCLOPHOSPHAMIDE (SANDOZ) APPROVAL= AP YEAR= 2023
NDA 217651 (label) INN (CYCLOPHOSPHAMIDE) CYCLOPHOSPHAMIDE (BAXTER HLTHCARE CORP) APPROVAL= AP YEAR= 2023
NDA 216783 (pdf not found) INN (CYCLOPHOSPHAMIDE) CYCLOPHOSPHAMIDE (NEXUS) APPROVAL= AP YEAR= 2024
NDA 218282 (pdf not found) INN (CYCLOPHOSPHAMIDE) CYCLOPHOSPHAMIDE (TRI-SOURCE PHARMA) APPROVAL= AP YEAR= 2024
NDA 218632 (pdf not found) INN (CYCLOPHOSPHAMIDE) CYCLOPHOSPHAMIDE (HAINAN POLY) APPROVAL= AP YEAR= 2024
NDA 218644 (pdf not found) INN (CYCLOPHOSPHAMIDE) CYCLOPHOSPHAMIDE (EPIC PHARMA LLC) APPROVAL= AP YEAR= 2024