e-Drug3D

270

BIPERIDEN

DISCONTINUED

INN
BIPERIDEN

cas 514-65-8

CLASS

NERVOUS SYSTEM
ANTIPARKINSONIAN
PERIPHERAL ANTICHOLINERGIC
ANTISPASMODIC
ANTIDYSKINETICS
MUSCARINIC ANTAGONISTS
PARASYMPATHOLYTICS

ROUTE (list)

ORAL INJECTION

ATC code

N04AA02

PK parameters

Tmax 1.25 HOUR
VD 780 LITER (65 KILOGRAM)
Cl 46.8 LITER / HOUR (65 KILOGRAM)
PPB 90 PERCENT
t1/2 24 HOUR

Solubility

SLIGHTLY SOLUBLE IN WATER

Target

TARGET MUSCARINIC ACETYLCHOLINE RECEPTOR

DrugCentral

Muscarinic acetylcholine receptor M1 UNIPROT P11229 CHRM1

Download SDF file

1-(6-bicyclo[2.2.1]hept-2-enyl)-1-phenyl-3-piperidin-1-ylpropan-1-ol

Formula:
C21H29NO

Calculated chemical properties:

MW 311.45
NB_atoms 23
XLogP 3.96
PSA 18.338
NB_HD 1
NB_HA 2
fsp3 0.62
Lipinski(0=no;1=yes) 1

FDA
NDA 012003 (pdf not found) INN (BIPERIDEN HYDROCHLORIDE) AKINETON (ABBVIE) APPROVAL= AP YEAR= 1959 DISCONTINUED
NDA 012418 (pdf not found) INN (BIPERIDEN LACTATE) AKINETON (ABBVIE) APPROVAL= AP YEAR= 1961 DISCONTINUED