e-Drug3D

261

DEMECARIUM

DISCONTINUED

INN
DEMECARIUM

cas 16505-84-3

CLASS

SENSORY
CHOLINERGIC
MIOTICS
TREATMENT OF OPEN-ANGLE GLAUCOMA
VASODILATATION
ERYTHROCYTE CHOLINESTERASE INHIBITOR

ROUTE (list)

OPHTHALMIC

ATC code

S01EB04

PK parameters

Target

TARGET CHOLINESTERASE

Acetylcholinesterase UNIPROT P22303 ACHE

Download SDF file

trimethyl-[3-[methyl-[10-[methyl-(3-trimethylazaniumylphenoxy)carbonylamino]decyl]carbamoyl]oxyphenyl]azanium dibromide

Formula:
C32H52N4O4

Calculated chemical properties:

MW 556.78
NB_atoms 40
XLogP 6.76
PSA 54.526
NB_HD 0
NB_HA 6
fsp3 0.56
Lipinski(0=no;1=yes) 0

FDA
NDA 011860 (pdf not found) INN (DEMECARIUM BROMIDE) HUMORSOL (MERCK) APPROVAL= AP YEAR= 1959 DISCONTINUED