e-Drug3D

259

METHDILAZINE

DISCONTINUED

INN
METHDILAZINE

cas 1982-37-2

CLASS

RESPIRATORY SYSTEM
ANTIHISTAMINES
ANTIPRURITIC
PHENOTIAZINE

ROUTE (list)

ORAL

ATC code

R06AD04

PK parameters

Target

TARGET HISTAMINE H1 RECEPTOR

DrugCentral

Histamine H1 receptor UNIPROT P35367 HRH1

Download SDF file

10-[(1-methylpyrrolidin-3-yl)methyl]phenothiazine

Formula:
C18H20N2S

Calculated chemical properties:

MW 296.43
NB_atoms 21
XLogP 4.24
PSA 9.007
NB_HD 0
NB_HA 2
fsp3 0.33
Lipinski(0=no;1=yes) 1

FDA
NDA 011950 (pdf not found) INN (METHDILAZINE) TACARYL (WESTWOOD SQUIBB) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 087122 (pdf not found) INN (METHDILAZINE HYDROCHLORIDE) METHDILAZINE HYDROCHLORIDE (ALPHARMA US PHARMS) APPROVAL= AP YEAR= 1981 DISCONTINUED