e-Drug3D

248

cas 52-24-4

CLASS

ANTINEOPLASTIC
ALKYLATING AGENT OF DNA

ROUTE (list)

INJECTION INTRACAVITARY INTRAVENOUS INTRAVESICAL

PK parameters

VD 104 LITER (65 KILOGRAM)
Cl 25.14 LITER / HOUR
PPB 10 PERCENT
t1/2 2.4 HOUR

MW 189.23
NB_atoms 11
XLogP 0.16
PSA 19.433
NB_HD 0
NB_HA 3
fsp3 1.00
Lipinski(0=no;1=yes) 1

FDA
NDA 011683 (pdf not found) INN (THIOTEPA) THIOTEPA (IMMUNEX) APPROVAL= AP YEAR= 1959 NEWMOLECULARENTITY DISCONTINUED
NDA 020058 (pdf not found) INN (THIOTEPA) THIOPLEX (IMMUNEX) APPROVAL= AP YEAR= 1994 DISCONTINUED
NDA 075547 (pdf not found) INN (THIOTEPA) THIOTEPA (WEST-WARD PHARMS INT) APPROVAL= AP YEAR= 2001
NDA 075698 (pdf not found) INN (THIOTEPA) THIOTEPA (FRESENIUS KABI USA) APPROVAL= AP YEAR= 2001 DISCONTINUED
NDA 075730 (pdf not found) INN (THIOTEPA) THIOTEPA (TEVA PARENTERAL) APPROVAL= AP YEAR= 2001 DISCONTINUED
NDA 208264 (pdf not found) INN (THIOTEPA) TEPADINA (ADIENNE SA) APPROVAL= AP YEAR= 2017
NDA 209150 (pdf not found) INN (THIOTEPA) THIOTEPA (HENGRUI PHARMA) APPROVAL= AP YEAR= 2018
NDA 210337 (pdf not found) INN (THIOTEPA) THIOTEPA (DR REDDYS) APPROVAL= AP YEAR= 2018
NDA 208242 (pdf not found) INN (THIOTEPA) THIOTEPA (PENN LIFE) APPROVAL= AP YEAR= 2020
NDA 213049 (pdf not found) INN (THIOTEPA) THIOTEPA (MSN) APPROVAL= AP YEAR= 2020
NDA 214222 (pdf not found) INN (THIOTEPA) THIOTEPA (GLAND) APPROVAL= AP YEAR= 2021
NDA 211831 (pdf not found) INN (THIOTEPA) THIOTEPA (BELOTECA) APPROVAL= AP YEAR= 2021
NDA 211755 (pdf not found) INN (THIOTEPA) THIOTEPA (HIKMA) APPROVAL= AP YEAR= 2023
NDA 216037 (pdf not found) INN (THIOTEPA) THIOTEPA (MEITHEAL) APPROVAL= AP YEAR= 2023
NDA 216984 (pdf not found) INN (THIOTEPA) TEPYLUTE (SHORLA) APPROVAL= AP YEAR= 2024
NDA 217559 (pdf not found) INN (THIOTEPA) THIOTEPA (BELOTECA) APPROVAL= AP YEAR= 2024