e-Drug3D
229
DEXTROMETHORPHAN
INN
DEXTROMETHORPHAN
cas 125-71-3
CLASS
NERVOUS SYSTEM
ANTITUSSIVE
UNCOMPETITIVE GLUTAMATE [NMDA] RECEPTOR ANTAGONIST
SIGMA 1-TYPE RECEPTOR AGONIST
TREATMENT OF PSEUDOBULBAR AFFECT (PBA)
SEROTONIN AND NOREPINEPHRINE REUPTAKE INHIBITOR
ROUTE (list)
ORAL
PK parameters
Tmax 3.5 HOUR
PPB 65 PERCENT
t1/2 13 HOUR
TARGET SIGMA 1-TYPE OPIOID RECEPTOR
GLUTAMATE [NMDA] RECEPTOR
Unknown
Formula:
C18H25NO
Calculated chemical properties:
MW 271.39
NB_atoms 20
XLogP 3.38
PSA 16.81
NB_HD 0
NB_HA 2
fsp3 0.67
Lipinski(0=no;1=yes) 1
NB_atoms 20
XLogP 3.38
PSA 16.81
NB_HD 0
NB_HA 2
fsp3 0.67
Lipinski(0=no;1=yes) 1
FDA
NDA 088722 (pdf not found) INN (BROMPHENIRAMINE MALEATE ; DEXTROMETHORPHAN HYDROBROMIDE ; PSEUDOEPHEDRINE HYDROCHLORIDE) BROMANATE DM (ALPHARMA US PHARMS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 011265 (label) INN (DEXTROMETHORPHAN HYDROBROMIDE ; PROMETHAZINE HYDROCHLORIDE) PROMETHAZINE HYDROCHLORIDE AND DEXTROMETHORPHAN HYDROBROMIDE (ANI PHARMS) APPROVAL= AP YEAR= 1957 DISCONTINUED
NDA 018658 (label) INN (DEXTROMETHORPHAN POLISTIREX) DELSYM (RB HLTH) APPROVAL= AP YEAR= 1982
NDA 019279 (label) INN (BROMPHENIRAMINE MALEATE ; DEXTROMETHORPHAN HYDROBROMIDE ; PSEUDOEPHEDRINE HYDROCHLORIDE) DIMETANE-DX (ROBINS AH) APPROVAL= AP YEAR= 1984 DISCONTINUED
NDA 088762 (pdf not found) INN (DEXTROMETHORPHAN HYDROBROMIDE ; PROMETHAZINE HYDROCHLORIDE) PROMETH W/ DEXTROMETHORPHAN (G AND W LABS INC) APPROVAL= AP YEAR= 1984 DISCONTINUED
NDA 088811 (pdf not found) INN (BROMPHENIRAMINE MALEATE ; DEXTROMETHORPHAN HYDROBROMIDE ; PSEUDOEPHEDRINE HYDROCHLORIDE) BROMFED-DM (WOCKHARDT BIO AG) APPROVAL= AP YEAR= 1985
NDA 088864 (pdf not found) INN (DEXTROMETHORPHAN HYDROBROMIDE ; PROMETHAZINE HYDROCHLORIDE) PROMETHAZINE W/ DEXTROMETHORPHAN (WOCKHARDT BIO AG) APPROVAL= AP YEAR= 1985
NDA 088913 (pdf not found) INN (DEXTROMETHORPHAN HYDROBROMIDE ; PROMETHAZINE HYDROCHLORIDE) PHERAZINE DM (HALSEY) APPROVAL= AP YEAR= 1987 DISCONTINUED
NDA 089681 (pdf not found) INN (BROMPHENIRAMINE MALEATE ; DEXTROMETHORPHAN HYDROBROMIDE ; PSEUDOEPHEDRINE HYDROCHLORIDE) BROMFED-DM (WOCKHARDT) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 040027 (pdf not found) INN (DEXTROMETHORPHAN HYDROBROMIDE ; PROMETHAZINE HYDROCHLORIDE) PROMETHAZINE HYDROCHLORIDE AND DEXTROMETHORPHAN HYDROBROMIDE (HIKMA) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 021620 (label) INN (DEXTROMETHORPHAN HYDROBROMIDE ; GUAIFENESIN) MUCINEX DM (RB HLTH) APPROVAL= AP YEAR= 2004
NDA 040649 (pdf not found) INN (DEXTROMETHORPHAN HYDROBROMIDE ; PROMETHAZINE HYDROCHLORIDE) PROMETHAZINE DM (SLATE RUN PHARMA) APPROVAL= AP YEAR= 2006
NDA 021879 (label) INN (DEXTROMETHORPHAN HYDROBROMIDE ; QUINIDINE SULFATE) NUEDEXTA (AVANIR PHARMS) APPROVAL= AP YEAR= 2010
NDA 090575 (pdf not found) INN (DEXTROMETHORPHAN HYDROBROMIDE ; PROMETHAZINE HYDROCHLORIDE) PROMETHAZINE HYDROCHLORIDE AND DEXTROMETHORPHAN HYDROBROMIDE (AMNEAL PHARMS) APPROVAL= AP YEAR= 2011
NDA 091135 (pdf not found) INN (DEXTROMETHORPHAN POLISTIREX) DEXTROMETHORPHAN POLISTIREX (TRIS PHARMA INC) APPROVAL= AP YEAR= 2012
NDA 091687 (pdf not found) INN (DEXTROMETHORPHAN HYDROBROMIDE) PROMETHAZINE HYDROCHLORIDE AND DEXTROMETHORPHAN HYDROBROMIDE (TRIS PHARMA INC) APPROVAL= AP YEAR= 2012
NDA 202940 (pdf not found) INN (BROMPHENIRAMINE MALEATE ; DEXTROMETHORPHAN HYDROBROMIDE ; PSEUDOEPHEDRINE HYDROCHLORIDE) BROMPHENIRAMINE MALEATE, PSEUDOEPHEDRINE HYDROCHLORIDE AND DEXTROMETHORPHAN HYDROBROMIDE (PHARM ASSOC) APPROVAL= AP YEAR= 2014
NDA 205292 (pdf not found) INN (BROMPHENIRAMINE MALEATE ; DEXTROMETHORPHAN HYDROBROMIDE ; PSEUDOEPHEDRINE HYDROCHLORIDE) BROMPHENIRAMINE MALEATE, PSEUDOEPHEDRINE HYDROCHLORIDE AND DEXTROMETHORPHAN HYDROBROMIDE (PADAGIS US) APPROVAL= AP YEAR= 2014
NDA 202993 (pdf not found) INN (DEXTROMETHORPHAN HYDROBROMIDE ; QUINIDINE SULFATE) DEXTROMETHORPHAN HYDROBROMIDE AND QUINIDINE SULFATE (PAR PHARM INC) APPROVAL= TA YEAR= 2015
NDA 091070 (pdf not found) INN (DEXTROMETHORPHAN HYDROBROMIDE ; GUAIFENESIN) GUAIFENESIN AND DEXTROMETHORPHAN HYDROBROMIDE (ACTAVIS LABS FL) APPROVAL= AP YEAR= 2015
NDA 203375 (pdf not found) INN (BROMPHENIRAMINE MALEATE ; DEXTROMETHORPHAN HYDROBROMIDE ; PSEUDOEPHEDRINE HYDROCHLORIDE) BROMPHENIRAMINE MALEATE, PSEUDOEPHEDRINE HYDROCHLORIDE AND DEXTROMETHORPHAN HYDROBROMIDE (ACELLA) APPROVAL= AP YEAR= 2016
NDA 203133 (pdf not found) INN (DEXTROMETHORPHAN POLISTIREX) DEXTROMETHORPHAN POLISTIREX (AMNEAL) APPROVAL= AP YEAR= 2017
NDA 205112 (pdf not found) INN (BROMPHENIRAMINE MALEATE ; DEXTROMETHORPHAN HYDROBROMIDE ; PSEUDOEPHEDRINE HYDROCHLORIDE) BROMPHENIRAMINE MALEATE, PSEUDOEPHEDRINE HYDROCHLORIDE AND DEXTROMETHORPHAN HYDROBROMIDE (TARO) APPROVAL= AP YEAR= 2017
NDA 206941 (pdf not found) INN (DEXTROMETHORPHAN HYDROBROMIDE ; GUAIFENESIN) GUAIFENESIN AND DEXTROMETHORPHAN HYDROBROMIDE (AUROBINDO PHARMA) APPROVAL= AP YEAR= 2017
NDA 202934 (pdf not found) INN (DEXTROMETHORPHAN HYDROBROMIDE ; QUINIDINE SULFATE) DEXTROMETHORPHAN HYDROBROMIDE AND QUINIDINE SULFATE (ACTAVIS ELIZABETH) APPROVAL= AP YEAR= 2017
NDA 209692 (pdf not found) INN (DEXTROMETHORPHAN HYDROBROMIDE ; GUAIFENESIN) GUAIFENESIN AND DEXTROMETHORPHAN HYDROBROMIDE (AMNEAL PHARMS) APPROVAL= AP YEAR= 2018
NDA 207602 (pdf not found) INN (DEXTROMETHORPHAN HYDROBROMIDE ; GUAIFENESIN) GUAIFENESIN AND DEXTROMETHORPHAN HYDROBROMIDE (PERRIGO R AND D) APPROVAL= AP YEAR= 2018
NDA 207676 (pdf not found) INN (BROMPHENIRAMINE MALEATE ; DEXTROMETHORPHAN HYDROBROMIDE ; PSEUDOEPHEDRINE HYDROCHLORIDE) BROMPHENIRAMINE MALEATE, PSEUDOEPHEDRINE HYDROCHLORIDE AND DEXTROMETHORPHAN HYDROBROMIDE (DR REDDYS LABS SA) APPROVAL= AP YEAR= 2018
NDA 210647 (pdf not found) INN (BROMPHENIRAMINE MALEATE ; DEXTROMETHORPHAN HYDROBROMIDE ; PSEUDOEPHEDRINE HYDROCHLORIDE) BROMPHENIRAMINE MALEATE, PSEUDOEPHEDRINE HYDROCHLORIDE AND DEXTROMETHORPHAN HYDROBROMIDE (ALKEM LABS LTD) APPROVAL= AP YEAR= 2020
NDA 211170 (pdf not found) INN (BROMPHENIRAMINE MALEATE ; DEXTROMETHORPHAN HYDROBROMIDE ; PSEUDOEPHEDRINE HYDROCHLORIDE) BROMPHENIRAMINE MALEATE, PSEUDOEPHEDRINE HYDROCHLORIDE AND DEXTROMETHORPHAN HYDROBROMIDE (WES PHARMA INC) APPROVAL= AP YEAR= 2020
NDA 213125 (pdf not found) INN (BROMPHENIRAMINE MALEATE ; DEXTROMETHORPHAN HYDROBROMIDE ; PSEUDOEPHEDRINE HYDROCHLORIDE) BROMPHENIRAMINE MALEATE, PSEUDOEPHEDRINE HYDROCHLORIDE AND DEXTROMETHORPHAN HYDROBROMIDE (CHARTWELL MOLECULAR) APPROVAL= AP YEAR= 2020
NDA 202955 (pdf not found) INN (BROMPHENIRAMINE MALEATE ; DEXTROMETHORPHAN HYDROBROMIDE ; PSEUDOEPHEDRINE HYDROCHLORIDE) BROMPHENIRAMINE MALEATE, PSEUDOEPHEDRINE HYDROCHLORIDE AND DEXTROMETHORPHAN HYDROBROMIDE (RHODES PHARMS) APPROVAL= AP YEAR= 2020 DISCONTINUED
NDA 203997 (pdf not found) INN (BROMPHENIRAMINE MALEATE ; DEXTROMETHORPHAN HYDROBROMIDE ; PSEUDOEPHEDRINE HYDROCHLORIDE) BROMPHENIRAMINE MALEATE, PSEUDOEPHEDRINE HYDROCHLORIDE AND DEXTROMETHORPHAN HYDROBROMIDE (BIONPHARMA) APPROVAL= AP YEAR= 2020 DISCONTINUED
NDA 214781 (pdf not found) INN (DEXTROMETHORPHAN HYDROBROMIDE ; GUAIFENESIN) GUAIFENESIN AND DEXTROMETHORPHAN HYDROBROMIDE (SUN PHARM) APPROVAL= AP YEAR= 2021
NDA 215430 (label) INN (BUPROPION HYDROCHLORIDE ; DEXTROMETHORPHAN HYDROBROMIDE) AUVELITY (AXSOME) APPROVAL= AP YEAR= 2022
NDA 217340 (pdf not found) INN (DEXTROMETHORPHAN HYDROBROMIDE ; GUAIFENESIN) GUAIFENESIN AND DEXTROMETHORPHAN HYDROBROMIDE (DR REDDYS) APPROVAL= AP YEAR= 2023
NDA 218426 (pdf not found) INN (DEXTROMETHORPHAN HYDROBROMIDE ; QUINIDINE SULFATE) DEXTROMETHORPHAN HYDROBROMIDE AND QUINIDINE SULFATE (HETERO LABS LTD III) APPROVAL= AP YEAR= 2024
NDA 088722 (pdf not found) INN (BROMPHENIRAMINE MALEATE ; DEXTROMETHORPHAN HYDROBROMIDE ; PSEUDOEPHEDRINE HYDROCHLORIDE) BROMANATE DM (ALPHARMA US PHARMS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 011265 (label) INN (DEXTROMETHORPHAN HYDROBROMIDE ; PROMETHAZINE HYDROCHLORIDE) PROMETHAZINE HYDROCHLORIDE AND DEXTROMETHORPHAN HYDROBROMIDE (ANI PHARMS) APPROVAL= AP YEAR= 1957 DISCONTINUED
NDA 018658 (label) INN (DEXTROMETHORPHAN POLISTIREX) DELSYM (RB HLTH) APPROVAL= AP YEAR= 1982
NDA 019279 (label) INN (BROMPHENIRAMINE MALEATE ; DEXTROMETHORPHAN HYDROBROMIDE ; PSEUDOEPHEDRINE HYDROCHLORIDE) DIMETANE-DX (ROBINS AH) APPROVAL= AP YEAR= 1984 DISCONTINUED
NDA 088762 (pdf not found) INN (DEXTROMETHORPHAN HYDROBROMIDE ; PROMETHAZINE HYDROCHLORIDE) PROMETH W/ DEXTROMETHORPHAN (G AND W LABS INC) APPROVAL= AP YEAR= 1984 DISCONTINUED
NDA 088811 (pdf not found) INN (BROMPHENIRAMINE MALEATE ; DEXTROMETHORPHAN HYDROBROMIDE ; PSEUDOEPHEDRINE HYDROCHLORIDE) BROMFED-DM (WOCKHARDT BIO AG) APPROVAL= AP YEAR= 1985
NDA 088864 (pdf not found) INN (DEXTROMETHORPHAN HYDROBROMIDE ; PROMETHAZINE HYDROCHLORIDE) PROMETHAZINE W/ DEXTROMETHORPHAN (WOCKHARDT BIO AG) APPROVAL= AP YEAR= 1985
NDA 088913 (pdf not found) INN (DEXTROMETHORPHAN HYDROBROMIDE ; PROMETHAZINE HYDROCHLORIDE) PHERAZINE DM (HALSEY) APPROVAL= AP YEAR= 1987 DISCONTINUED
NDA 089681 (pdf not found) INN (BROMPHENIRAMINE MALEATE ; DEXTROMETHORPHAN HYDROBROMIDE ; PSEUDOEPHEDRINE HYDROCHLORIDE) BROMFED-DM (WOCKHARDT) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 040027 (pdf not found) INN (DEXTROMETHORPHAN HYDROBROMIDE ; PROMETHAZINE HYDROCHLORIDE) PROMETHAZINE HYDROCHLORIDE AND DEXTROMETHORPHAN HYDROBROMIDE (HIKMA) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 021620 (label) INN (DEXTROMETHORPHAN HYDROBROMIDE ; GUAIFENESIN) MUCINEX DM (RB HLTH) APPROVAL= AP YEAR= 2004
NDA 040649 (pdf not found) INN (DEXTROMETHORPHAN HYDROBROMIDE ; PROMETHAZINE HYDROCHLORIDE) PROMETHAZINE DM (SLATE RUN PHARMA) APPROVAL= AP YEAR= 2006
NDA 021879 (label) INN (DEXTROMETHORPHAN HYDROBROMIDE ; QUINIDINE SULFATE) NUEDEXTA (AVANIR PHARMS) APPROVAL= AP YEAR= 2010
NDA 090575 (pdf not found) INN (DEXTROMETHORPHAN HYDROBROMIDE ; PROMETHAZINE HYDROCHLORIDE) PROMETHAZINE HYDROCHLORIDE AND DEXTROMETHORPHAN HYDROBROMIDE (AMNEAL PHARMS) APPROVAL= AP YEAR= 2011
NDA 091135 (pdf not found) INN (DEXTROMETHORPHAN POLISTIREX) DEXTROMETHORPHAN POLISTIREX (TRIS PHARMA INC) APPROVAL= AP YEAR= 2012
NDA 091687 (pdf not found) INN (DEXTROMETHORPHAN HYDROBROMIDE) PROMETHAZINE HYDROCHLORIDE AND DEXTROMETHORPHAN HYDROBROMIDE (TRIS PHARMA INC) APPROVAL= AP YEAR= 2012
NDA 202940 (pdf not found) INN (BROMPHENIRAMINE MALEATE ; DEXTROMETHORPHAN HYDROBROMIDE ; PSEUDOEPHEDRINE HYDROCHLORIDE) BROMPHENIRAMINE MALEATE, PSEUDOEPHEDRINE HYDROCHLORIDE AND DEXTROMETHORPHAN HYDROBROMIDE (PHARM ASSOC) APPROVAL= AP YEAR= 2014
NDA 205292 (pdf not found) INN (BROMPHENIRAMINE MALEATE ; DEXTROMETHORPHAN HYDROBROMIDE ; PSEUDOEPHEDRINE HYDROCHLORIDE) BROMPHENIRAMINE MALEATE, PSEUDOEPHEDRINE HYDROCHLORIDE AND DEXTROMETHORPHAN HYDROBROMIDE (PADAGIS US) APPROVAL= AP YEAR= 2014
NDA 202993 (pdf not found) INN (DEXTROMETHORPHAN HYDROBROMIDE ; QUINIDINE SULFATE) DEXTROMETHORPHAN HYDROBROMIDE AND QUINIDINE SULFATE (PAR PHARM INC) APPROVAL= TA YEAR= 2015
NDA 091070 (pdf not found) INN (DEXTROMETHORPHAN HYDROBROMIDE ; GUAIFENESIN) GUAIFENESIN AND DEXTROMETHORPHAN HYDROBROMIDE (ACTAVIS LABS FL) APPROVAL= AP YEAR= 2015
NDA 203375 (pdf not found) INN (BROMPHENIRAMINE MALEATE ; DEXTROMETHORPHAN HYDROBROMIDE ; PSEUDOEPHEDRINE HYDROCHLORIDE) BROMPHENIRAMINE MALEATE, PSEUDOEPHEDRINE HYDROCHLORIDE AND DEXTROMETHORPHAN HYDROBROMIDE (ACELLA) APPROVAL= AP YEAR= 2016
NDA 203133 (pdf not found) INN (DEXTROMETHORPHAN POLISTIREX) DEXTROMETHORPHAN POLISTIREX (AMNEAL) APPROVAL= AP YEAR= 2017
NDA 205112 (pdf not found) INN (BROMPHENIRAMINE MALEATE ; DEXTROMETHORPHAN HYDROBROMIDE ; PSEUDOEPHEDRINE HYDROCHLORIDE) BROMPHENIRAMINE MALEATE, PSEUDOEPHEDRINE HYDROCHLORIDE AND DEXTROMETHORPHAN HYDROBROMIDE (TARO) APPROVAL= AP YEAR= 2017
NDA 206941 (pdf not found) INN (DEXTROMETHORPHAN HYDROBROMIDE ; GUAIFENESIN) GUAIFENESIN AND DEXTROMETHORPHAN HYDROBROMIDE (AUROBINDO PHARMA) APPROVAL= AP YEAR= 2017
NDA 202934 (pdf not found) INN (DEXTROMETHORPHAN HYDROBROMIDE ; QUINIDINE SULFATE) DEXTROMETHORPHAN HYDROBROMIDE AND QUINIDINE SULFATE (ACTAVIS ELIZABETH) APPROVAL= AP YEAR= 2017
NDA 209692 (pdf not found) INN (DEXTROMETHORPHAN HYDROBROMIDE ; GUAIFENESIN) GUAIFENESIN AND DEXTROMETHORPHAN HYDROBROMIDE (AMNEAL PHARMS) APPROVAL= AP YEAR= 2018
NDA 207602 (pdf not found) INN (DEXTROMETHORPHAN HYDROBROMIDE ; GUAIFENESIN) GUAIFENESIN AND DEXTROMETHORPHAN HYDROBROMIDE (PERRIGO R AND D) APPROVAL= AP YEAR= 2018
NDA 207676 (pdf not found) INN (BROMPHENIRAMINE MALEATE ; DEXTROMETHORPHAN HYDROBROMIDE ; PSEUDOEPHEDRINE HYDROCHLORIDE) BROMPHENIRAMINE MALEATE, PSEUDOEPHEDRINE HYDROCHLORIDE AND DEXTROMETHORPHAN HYDROBROMIDE (DR REDDYS LABS SA) APPROVAL= AP YEAR= 2018
NDA 210647 (pdf not found) INN (BROMPHENIRAMINE MALEATE ; DEXTROMETHORPHAN HYDROBROMIDE ; PSEUDOEPHEDRINE HYDROCHLORIDE) BROMPHENIRAMINE MALEATE, PSEUDOEPHEDRINE HYDROCHLORIDE AND DEXTROMETHORPHAN HYDROBROMIDE (ALKEM LABS LTD) APPROVAL= AP YEAR= 2020
NDA 211170 (pdf not found) INN (BROMPHENIRAMINE MALEATE ; DEXTROMETHORPHAN HYDROBROMIDE ; PSEUDOEPHEDRINE HYDROCHLORIDE) BROMPHENIRAMINE MALEATE, PSEUDOEPHEDRINE HYDROCHLORIDE AND DEXTROMETHORPHAN HYDROBROMIDE (WES PHARMA INC) APPROVAL= AP YEAR= 2020
NDA 213125 (pdf not found) INN (BROMPHENIRAMINE MALEATE ; DEXTROMETHORPHAN HYDROBROMIDE ; PSEUDOEPHEDRINE HYDROCHLORIDE) BROMPHENIRAMINE MALEATE, PSEUDOEPHEDRINE HYDROCHLORIDE AND DEXTROMETHORPHAN HYDROBROMIDE (CHARTWELL MOLECULAR) APPROVAL= AP YEAR= 2020
NDA 202955 (pdf not found) INN (BROMPHENIRAMINE MALEATE ; DEXTROMETHORPHAN HYDROBROMIDE ; PSEUDOEPHEDRINE HYDROCHLORIDE) BROMPHENIRAMINE MALEATE, PSEUDOEPHEDRINE HYDROCHLORIDE AND DEXTROMETHORPHAN HYDROBROMIDE (RHODES PHARMS) APPROVAL= AP YEAR= 2020 DISCONTINUED
NDA 203997 (pdf not found) INN (BROMPHENIRAMINE MALEATE ; DEXTROMETHORPHAN HYDROBROMIDE ; PSEUDOEPHEDRINE HYDROCHLORIDE) BROMPHENIRAMINE MALEATE, PSEUDOEPHEDRINE HYDROCHLORIDE AND DEXTROMETHORPHAN HYDROBROMIDE (BIONPHARMA) APPROVAL= AP YEAR= 2020 DISCONTINUED
NDA 214781 (pdf not found) INN (DEXTROMETHORPHAN HYDROBROMIDE ; GUAIFENESIN) GUAIFENESIN AND DEXTROMETHORPHAN HYDROBROMIDE (SUN PHARM) APPROVAL= AP YEAR= 2021
NDA 215430 (label) INN (BUPROPION HYDROCHLORIDE ; DEXTROMETHORPHAN HYDROBROMIDE) AUVELITY (AXSOME) APPROVAL= AP YEAR= 2022
NDA 217340 (pdf not found) INN (DEXTROMETHORPHAN HYDROBROMIDE ; GUAIFENESIN) GUAIFENESIN AND DEXTROMETHORPHAN HYDROBROMIDE (DR REDDYS) APPROVAL= AP YEAR= 2023
NDA 218426 (pdf not found) INN (DEXTROMETHORPHAN HYDROBROMIDE ; QUINIDINE SULFATE) DEXTROMETHORPHAN HYDROBROMIDE AND QUINIDINE SULFATE (HETERO LABS LTD III) APPROVAL= AP YEAR= 2024