e-Drug3D

218

cas 59-67-6

CLASS

CARDIOVASCULAR
VITAMIN B3
ANTILIPEMIC AGENTS
PARTIAL INHIBITION OF RELEASE OF FREE FATTY ACIDS FROM ADIPOSE TISSUE
INCREASED LIPOPROTEIN LIPASE ACTIVITY

ROUTE (list)

ORAL

PK parameters

Tmax 5 HOUR
PPB 20 PERCENT
t1/2 0.56 HOUR

-

PDB
1ICV (THE STRUCTURE OF ESCHERICHIA COLI NITROREDUCTASE COMPLEXED WITH NICOTINIC ACID)

Ligand code = NIO (link to the list of PDB complexes)

Download experimental 3D coordinates of NIO with added hydrogens

MW 122.10
NB_atoms 9
XLogP -0.55
PSA 45.551
NB_HD 0
NB_HA 3
fsp3 0.00
Lipinski(0=no;1=yes) 1

FDA
NDA 083115 (pdf not found) INN (NIACIN) NIACIN (IMPAX LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 083203 (pdf not found) INN (NIACIN) NIACIN (EVERYLIFE) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 083271 (pdf not found) INN (NIACIN) NIACIN (PUREPAC PHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 083306 (pdf not found) INN (NIACIN) NIACIN (SANDOZ) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 083453 (pdf not found) INN (NIACIN) NIACIN (HALSEY) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 084237 (pdf not found) INN (NIACIN) NIACIN (TABLICAPS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 011073 (pdf not found) INN (NIACIN) WAMPOCAP (MEDPOINTE PHARM HLC) APPROVAL= AP YEAR= 1957 DISCONTINUED
NDA 083180 (pdf not found) INN (NIACIN) NIACIN (IVAX SUB TEVA PHARMS) APPROVAL= AP YEAR= 1972 DISCONTINUED
NDA 083136 (pdf not found) INN (NIACIN) NIACIN (WATSON LABS) APPROVAL= AP YEAR= 1973 DISCONTINUED
NDA 083305 (pdf not found) INN (NIACIN) NIACIN (WATSON LABS) APPROVAL= AP YEAR= 1973 DISCONTINUED
NDA 083525 (pdf not found) INN (NIACIN) NIACIN (MK LABS) APPROVAL= AP YEAR= 1973 DISCONTINUED
NDA 083823 (pdf not found) INN (NIACIN) NICOLAR (SANOFI AVENTIS US) APPROVAL= AP YEAR= 1973 DISCONTINUED
NDA 083718 (pdf not found) INN (NIACIN) NIACIN (HIKMA) APPROVAL= AP YEAR= 1974 DISCONTINUED
NDA 085172 (pdf not found) INN (NIACIN) NIACIN (WATSON LABS) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 081134 (pdf not found) INN (NIACIN) NIACIN (WOCKHARDT) APPROVAL= AP YEAR= 1992 DISCONTINUED
NDA 020381 (pdf not found) INN (NIACIN) NIASPAN (ABBVIE) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 040378 (pdf not found) INN (NIACIN) NIACOR (AVONDALE PHARMS) APPROVAL= AP YEAR= 2000
NDA 021249 (pdf not found) INN (NIACIN) ADVICOR (ABBVIE) APPROVAL= AP YEAR= 2001 OBSOLETE
NDA 076250 (pdf not found) INN (NIACIN) NIACIN (BARR) APPROVAL= AP YEAR= 2005
NDA 076378 (pdf not found) INN (NIACIN) NIACIN (BARR) APPROVAL= AP YEAR= 2005
NDA 022078 (pdf not found) INN (NIACIN) SIMCOR (ABBVIE) APPROVAL= AP YEAR= 2008 OBSOLETE
NDA 090446 (pdf not found) INN (NIACIN) NIACIN (CHARTWELL RX) APPROVAL= AP YEAR= 2014
NDA 090860 (pdf not found) INN (NIACIN) NIACIN (CHARTWELL RX) APPROVAL= AP YEAR= 2014
NDA 090892 (pdf not found) INN (NIACIN) NIACIN (CHARTWELL RX) APPROVAL= AP YEAR= 2014
NDA 200484 (pdf not found) INN (NIACIN) NIACIN (SUN PHARM) APPROVAL= AP YEAR= 2014
NDA 201273 (pdf not found) INN (NIACIN) NIACIN (SUN PHARM) APPROVAL= AP YEAR= 2014
NDA 203578 (pdf not found) INN (NIACIN) NIACIN (AMNEAL PHARMS) APPROVAL= AP YEAR= 2015
NDA 204178 (pdf not found) INN (NIACIN) NIACIN (AMNEAL PHARMS) APPROVAL= AP YEAR= 2015
NDA 203899 (pdf not found) INN (NIACIN) NIACIN (LANNETT CO INC) APPROVAL= AP YEAR= 2017
NDA 209156 (pdf not found) INN (NIACIN) NIACIN (JUBILANT GENERICS) APPROVAL= AP YEAR= 2018 DISCONTINUED
NDA 209236 (pdf not found) INN (NIACIN) NIACIN (AUROBINDO PHARMA LTD) APPROVAL= AP YEAR= 2018
NDA 203742 (pdf not found) INN (NIACIN) NIACIN (RISING) APPROVAL= AP YEAR= 2019 DISCONTINUED
NDA 212017 (pdf not found) INN (NIACIN) NIACIN (YICHANG HUMANWELL) APPROVAL= AP YEAR= 2019 DISCONTINUED
NDA 214428 (pdf not found) INN (NIACIN) NIACIN (BEIJING) APPROVAL= AP YEAR= 2021 DISCONTINUED
NDA 204934 (pdf not found) INN (NIACIN) NIACIN (MACLEODS PHARMS LTD) APPROVAL= AP YEAR= 2022
NDA 213090 (pdf not found) INN (NIACIN) NIACIN (HIBROW HLTHCARE) APPROVAL= AP YEAR= 2023
NDA 203285 (pdf not found) INN (NIACIN) NIACIN (ZYDUS PHARMS) APPROVAL= AP YEAR= 2025
NDA 207726 (pdf not found) INN (NIACIN) NIACIN (MPP PHARMA) APPROVAL= AP YEAR= 2025