e-Drug3D

2154

SUZETRIGINE

INN
SUZETRIGINE

cas 2649467-58-1

CLASS

NERVOUS SYSTEM
SODIUM CHANNEL BLOCKER
TREATMENT OF MODERATE TO SEVERE ACUTE PAIN

ROUTE (list)

ORAL

ATC code

PK parameters

Tmax 3 HOUR
VD 495 LITER
Cl 13.9 LITER / HOUR
PPB 99 PERCENT
t1/2 23.6 HOUR

Solubility

PRACTICALLY INSOLUBLE IN WATER

Target

TARGET NAV1.8 VOLTAGE-GATED SODIUM CHANNEL

DrugCentral

Download SDF file

2-Pyridinecarboxamide, 4-[[[(2R,3S,4S,5R)-3-(3,4-difluoro-2-methoxyphenyl)tetrahydro-4,5-dimethyl-5-(trifluoromethyl)-2-furanyl]carbonyl]amino]- (ACI)

Formula:
C21H20F5N3O4

Calculated chemical properties:

MW 473.40
NB_atoms 33
XLogP 3.55
PSA 95.729
NB_HD 3
NB_HA 7
fsp3 0.38
Lipinski(0=no;1=yes) 1

FDA
NDA 219209 (label) INN (SUZETRIGINE) JOURNAVX (VERTEX PHARMS INC) APPROVAL= AP YEAR= 2025 NEWMOLECULARENTITY