e-Drug3D

2121

ARIMOCLOMOL

INN
ARIMOCLOMOL

cas 289893-25-0

CLASS

NERVOUS SYSTEM
COMBINATION WITH MIGLUSTAT FOR THE TREATMENT OF NEUROLOGICAL MANIFESTATIONS OF NIEMANN-PICK DISEASE TYPE C (NPC)

ROUTE (list)

ORAL

ATC code

N07XX17

PK parameters

Tmax 0.5 HOUR
VD 211 LITER
Cl 34 LITER / HOUR
PPB 10 PERCENT
t1/2 4 HOUR

Solubility

FREELY SOLUBLE IN WATER

Target

DrugCentral

Download SDF file

3-Pyridinecarboximidoyl chloride, N-[(2R)-2-hydroxy-3-(1-piperidinyl)propoxy]-, 1-oxide

Formula:
C14H20ClN3O3

Calculated chemical properties:

MW 313.78
NB_atoms 21
XLogP 1.08
PSA 70.866
NB_HD 1
NB_HA 5
fsp3 0.57
Lipinski(0=no;1=yes) 1

FDA
NDA 214927 (pdf not found) INN (ARIMOCLOMOL CITRATE) MIPLYFFA (ZEVRA DENMARK) APPROVAL= AP YEAR= 2024 NEWMOLECULARENTITY