e-Drug3D

2120

TREOSULFAN

INN
TREOSULFAN

cas 299-75-2

CLASS

ANTINEOPLASTIC
ALKYLATING DRUG
FOR ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION (ALLOHSCT)
ACUTE MYELOID LEUKEMIA (AML)
MYELODYSPLASTIC SYNDROME (MDS)

ROUTE (list)

INTRAVENOUS

ATC code

L01AB02

PK parameters

VD 41 LITER
PPB 0 PERCENT
t1/2 1.7 HOUR

Solubility

SOLUBLE IN WATER

Target

TARGET DNA

DrugCentral

Unknown

Download SDF file

1,2,3,4-Butanetetrol, 1,4-dimethanesulfonate, (2S,3S)-

Formula:
C6H14O8S2

Calculated chemical properties:

MW 278.31
NB_atoms 16
XLogP -2.34
PSA 127.444
NB_HD 2
NB_HA 8
fsp3 1.00
Lipinski(0=no;1=yes) 1

FDA
NDA 214759 (pdf not found) INN (TREOSULFAN) GRAFAPEX (MEDEXUS) APPROVAL= AP YEAR= 2025 NEWMOLECULARENTITY