e-Drug3D

2116

BENZQUINAMIDE

DISCONTINUED

INN
BENZQUINAMIDE

cas 63-12-7

CLASS

ANTIEMETIC
ANTIPSYCHOTICS
NERVOUS SYSTEM

ROUTE (list)

RECTAL INJECTION

ATC code

PK parameters

F 39 PERCENT (PMID:581593)
t1/2 1.3 HOUR (PMID581593)

Target

TARGET P-GLYCOPROTEIN (PMID1362504)

DrugCentral

D(2) dopamine receptor UNIPROT P14416 DRD2

Download SDF file

[3-(diethylcarbamoyl)-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-2-yl] acetate

Formula:
C22H32N2O5

Calculated chemical properties:

MW 404.50
NB_atoms 29
XLogP 2.42
PSA 67.329
NB_HD 0
NB_HA 7
fsp3 0.64
Lipinski(0=no;1=yes) 1

FDA
NDA 016820 (pdf not found) INN (BENZQUINAMIDE HYDROCHLORIDE) EMETE-CON (PFIZER) APPROVAL= AP YEAR= 1974 DISCONTINUED
NDA 016818 (pdf not found) INN (BENZQUINAMIDE HYDROCHLORIDE) EMETE-CON (ROERIG) APPROVAL= AP YEAR= 1978 DISCONTINUED