e-Drug3D

2100

SOFPIRONIUM

INN
SOFPIRONIUM

cas 1628251-49-9

CLASS

DERMATOLOGICALS
ANTICHOLINERGIC DRUG
COMPETITIVE INHIBITOR OF ACETYLCHOLINE RECEPTOR

ROUTE (list)

TOPICAL

ATC code

PK parameters

Tmax 5.34 HOUR
PPB 36.3 PERCENT

Solubility

FREELY SOLUBLE IN WATER

Target

TARGET MUSCARINIC ACETYLCHOLINE RECEPTOR M3

Muscarinic acetylcholine receptor M3 UNIPROT P20309

Download SDF file

Pyrrolidinium, 3-[[(2R)-2-cyclopentyl-2-hydroxy-2-phenylacetyl]oxy]-1-(2-ethoxy-2-oxoethyl)-1-methyl-, (3R)- (ACI)

Formula:
C22H32NO5

Calculated chemical properties:

MW 390.49
NB_atoms 28
XLogP 2.39
PSA 63.438
NB_HD 1
NB_HA 5
fsp3 0.64
Lipinski(0=no;1=yes) 1

FDA
NDA 217347 (pdf not found) INN (SOFPIRONIUM BROMIDE) SOFDRA (BOTANIX SB) APPROVAL= AP YEAR= 2024 NEWMOLECULARENTITY