e-Drug3D

ESTRADIOL ACETATE

INN
ESTRADIOL ACETATE

(has an active metabolite)

cas 4245-41-4

CLASS

GENITO
ESTROGEN
RAPIDLY HYDROLYZED IN ESTRADIOL

ROUTE (list)

VAGINAL ORAL

ATC code

G03AB08
H01CC53
G03CA03
G03CA53
G03AA17
G03AA14
H01CC54

PK parameters

Target

TARGET ESTROGEN RECEPTOR

DrugCentral

Estrogen receptor UNIPROT P03372 ESR1

Download SDF file

[(8R,9S,13S,14S)-3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] acetate

Formula:
C20H26O3

Calculated chemical properties:

MW 314.41
NB_atoms 23
XLogP 3.83
PSA 46.142
NB_HD 1
NB_HA 3
fsp3 0.65
Lipinski(0=no;1=yes) 1

FDA
NDA 021367 (label) INN (ESTRADIOL ACETATE) FEMRING (MILLICENT PR) APPROVAL= AP YEAR= 2003
NDA 021633 (label) INN (ESTRADIOL ACETATE) FEMTRACE (APIL) APPROVAL= AP YEAR= 2004 DISCONTINUED