e-Drug3D

2097

ETRASIMOD

INN
ETRASIMOD

cas 1206123-37-6

CLASS

IMMUNOSUPPRESSANTS
IMMUNOMODULATING AGENTS
SPHINGOSINE 1-PHOSPHATE (S1P) RECEPTOR MODULATOR
TREATMENT OF MODERATELY TO SEVERELY ACTIVE ULCERATIVE COLITIS

ROUTE (list)

ORAL

ATC code

L04AE05

PK parameters

Tmax 4 HOUR
VD 66 LITER
Cl 1 LITER / HOUR
PPB 97.9 PERCENT
t1/2 30 HOUR

Target

TARGET SPHINGOSINE 1-PHOSPHATE (S1P) RECEPTOR

DrugCentral

Download SDF file

Cyclopent[b]indole-3-acetic acid, 7-[[4-cyclopentyl-3-(trifluoromethyl)phenyl]methoxy]-1,2,3,4-tetrahydro-, (3R)- (ACI)

Formula:
C26H26F3NO3

Calculated chemical properties:

MW 456.47
NB_atoms 33
XLogP 5.59
PSA 59.292
NB_HD 1
NB_HA 4
fsp3 0.42
Lipinski(0=no;1=yes) 0

FDA
NDA 216956 (pdf not found) INN (ETRASIMOD ARGININE) VELSIPITY (PFIZER) APPROVAL= AP YEAR= 2023 NEWMOLECULARENTITY