e-Drug3D

2094

PIVMECILLINAM

INN
PIVMECILLINAM

cas 32886-97-8

CLASS

ANTIINFECTIVES
PENICILLIN
ANTIBACTERIAL
TREATMENT OF URINARY TRACT INFECTIONS CAUSED BY ESCHERICHIA COLI , PROTEUS MIRABILIS AND STAPHYLOCOCCUS SAPROPHYTICUS
RAPIDLY HYDROLYZED TO MECILLINAM BY NON-SPECIFIC ESTERASES

ROUTE (list)

ORAL

ATC code

PIVMECILLINAM

PK parameters

Target

TARGET PENICILLIN-BINDING PROTEIN 2B

DrugCentral

Peptidoglycan D,D-transpeptidase MrdA UNIPROT P0AD65

Download SDF file

4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(hexahydro-1H-azepin-1-yl)methylene]amino]-3,3-dimethyl-7-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, (2S,5R,6R)-

Formula:
C21H33N3O5S

Calculated chemical properties:

MW 439.57
NB_atoms 30
XLogP 2.41
PSA 85.258
NB_HD 0
NB_HA 8
fsp3 0.81
Lipinski(0=no;1=yes) 1

FDA
NDA 216483 (label) INN (PIVMECILLINAM HYDROCHLORIDE) PIVYA (UTILITY THERAP) APPROVAL= AP YEAR= 2024