e-Drug3D

2084

GEPIRONE

DISCONTINUED

INN
GEPIRONE

cas 83928-76-1

CLASS

NERVOUS SYSTEM
TREATMENT OF MAJOR DEPRESSIVE DISORDER (MDD) IN ADULTS
5HT1A RECEPTOR AGONIST

ROUTE (list)

ORAL

ATC code

N06AX19

PK parameters

F 15 PERCENT
Tmax 6 HOUR
VD 94.5 LITER
PPB 72 PERCENT
t1/2 5 HOUR

Solubility

READILY SOLUBLE IN WATER

Target

TARGET 5HT1A RECEPTOR

5-hydroxytryptamine receptor 1A UNIPROT P08908 HTR1A

Download SDF file

4,4-Dimethyl-1-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-2,6-piperidinedione

Formula:
C19H29N5O2

Calculated chemical properties:

MW 359.47
NB_atoms 26
XLogP 1.55
PSA 64.553
NB_HD 0
NB_HA 7
fsp3 0.68
Lipinski(0=no;1=yes) 1

FDA
NDA 021164 (label) INN (GEPIRONE HYDROCHLORIDE) EXXUA (FABRE KRAMER) APPROVAL= AP YEAR= 2023 DISCONTINUED