e-Drug3D

2078

TROFINETIDE

INN
TROFINETIDE

cas 853400-76-7

CLASS

NERVOUS SYSTEM
TREATMENT OF RETT SYNDROME

ROUTE (list)

ORAL

ATC code

N07XX24

PK parameters

Tmax 2.5 HOUR
VD 80 LITER
PPB 6 PERCENT
t1/2 1.5 HOUR

Solubility

FREELY SOLUBLE IN WATER

Target

DrugCentral

Unknown

Download SDF file

L-Glutamic acid, glycyl-2-methyl-L-prolyl- (9CI, ACI)

Formula:
C13H21N3O6

Calculated chemical properties:

MW 313.31
NB_atoms 22
XLogP -3.91
PSA 140.7
NB_HD 3
NB_HA 9
fsp3 0.69
Lipinski(0=no;1=yes) 0

FDA
NDA 217026 (label) INN (TROFINETIDE) DAYBUE (ACADIA PHARMS INC) APPROVAL= AP YEAR= 2023 NEWMOLECULARENTITY