e-Drug3D

2031

M ABROCITINIB

INN
ABROCITINIB

cas 2744171-53-5

CLASS

DERMATOLOGICALS
TREATMENT OF ATOPIC DERMATITIS
JANUS KINASE 1 (JAK1) INHIBITOR

ROUTE (list)

ATC code

D11AH08

PK parameters

PPB 29 PERCENT
t1/2 4 HOUR

Target

TARGET JAK1 KINASE

Tyrosine-protein kinase JAK1 UNIPROT P23458

Download SDF file

1-Propanesulfonamide, 2-hydroxy-N-[cis-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)cyclobutyl]-, (2R)- (ACI)

Formula:
C14H21N5O3S

Calculated chemical properties:

MW 339.43
NB_atoms 23
XLogP 0.23
PSA 105.841
NB_HD 3
NB_HA 8
fsp3 0.57
Lipinski(0=no;1=yes) 1

FDA
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