e-Drug3D

2025

M REMDESIVIR

INN
REMDESIVIR

cas 1191237-69-0

CLASS

ANTIINFECTIVES
SARS-COV-2 NUCLEOTIDE ANALOG RNA POLYMERASE INHIBITOR
ANTIVIRAL

ROUTE (list)

ATC code

J05AB16

PK parameters

Tmax 1.75 HOUR
PPB 2 PERCENT
t1/2 27 HOUR

Target

TARGET RNA POLYMERASE

PDB
7BF6 (CRYSTAL STRUCTURE OF SARS-COV-2 MACRODOMAIN IN COMPLEX WITH REMDESIVIR METABOLITE GS-441524)

Download experimental 3D coordinates of U08 with added hydrogens

Replicase polyprotein 1ab UNIPROT P0DTD1 REP

Download SDF file

D-Altrononitrile, 2-C-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-2,5-anhydro-

Formula:
C12H13N5O4

Calculated chemical properties:

MW 291.27
NB_atoms 21
XLogP -1.86
PSA 141.582
NB_HD 5
NB_HA 9
fsp3 0.42
Lipinski(0=no;1=yes) 0

FDA
-