e-Drug3D

2011

SETMELANOTIDE

INN
SETMELANOTIDE

cas 920014-72-8

CLASS

METABOLISM
MELANOCORTIN 4 (MC4) RECEPTOR AGONIST
CHRONIC WEIGHT MANAGEMENT
8 AMINO ACID CYCLIC PEPTIDE ANALOG OF ENDOGEN OUS MELANOCORTIN PEPTIDE ALPHA-MSH (ALPHA-MELANOCYTE STIMULATING HORMONE)

ROUTE (list)

SUBCUTANEOUS

ATC code

A08AA12

PK parameters

Tmax 8 HOUR
VD 48.7 LITER
Cl 4.86 LITER / HOUR
PPB 79.1 PERCENT
t1/2 11 HOUR

Target

TARGET MELANOCORTIN 4 (MC4) RECEPTOR

DrugCentral

Melanocortin receptor 4 UNIPROT P32245 MC4R

Download SDF file

L-Cysteinamide, N2-acetyl-L-arginyl-L-cysteinyl-D-alanyl-L-histidyl-D-phenylalanyl-L-arginyl-L-tryptophyl-, cyclic (2->8)-disulfide

Formula:
C49H68N18O9S2

Calculated chemical properties:

MW 1119.37
NB_atoms 78
XLogP -6.40
PSA 409.269
NB_HD 22
NB_HA 25
fsp3 0.43
Lipinski(0=no;1=yes) 0

FDA
NDA 213793 (label) INN (SETMELANOTIDE ACETATE) IMCIVREE (RHYTHM) APPROVAL= AP YEAR= 2020 NEWMOLECULARENTITY