e-Drug3D

2005

NIFURTIMOX

INN
NIFURTIMOX

cas 23256-30-6

CLASS

ANTIPARASITIC
ANTIPROTOZOAL
TREATMENT OF CHAGAS DISEASE CAUSED BY TRYPANOSOMA CRUZI
PRODUCTION OF TOXIC INTERMEDIATE METABOLITES AND/OR REACTIVE OXYGEN SPECIES THAT INDUCE DNA DAMAGE AND CELL DEATH

ROUTE (list)

ORAL

ATC code

P01CC01

PK parameters

Tmax 4 HOUR
PPB 42 PERCENT
t1/2 3 HOUR

Target

TARGET DNA

DrugCentral

Unknown

Download SDF file

4-Thiomorpholinamine, 3-methyl-N-[(5-nitro-2-furanyl)methylene]-, 1,1-dioxide

Formula:
C10H13N3O5S

Calculated chemical properties:

MW 287.30
NB_atoms 19
XLogP 0.64
PSA 105.143
NB_HD 0
NB_HA 7
fsp3 0.50
Lipinski(0=no;1=yes) 1

FDA
NDA 213464 (pdf not found) INN (NIFURTIMOX) LAMPIT (BAYER HEALTHCARE) APPROVAL= AP YEAR= 2020 NEWMOLECULARENTITY