e-Drug3D

200

cas 64-77-7

CLASS

METABOLISM
ANTIDIABETIC
HYPOGLYCEMIC AGENTS
SULFONYLUREAS
CHANNEL BLOCKER

ROUTE (list)

ORAL INJECTION

PK parameters

Tmax 3.8 HOUR
VD 7.8 LITER (65 KILOGRAM)
Cl 0.819 LITER / HOUR (65 KILOGRAM)
PPB 95 PERCENT
t1/2 7 HOUR

MW 270.35
NB_atoms 18
XLogP 1.78
PSA 73.177
NB_HD 2
NB_HA 5
fsp3 0.42
Lipinski(0=no;1=yes) 1

FDA
NDA 088950 (pdf not found) INN (TOLBUTAMIDE) TOLBUTAMIDE (PUREPAC PHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089110 (pdf not found) INN (TOLBUTAMIDE) TOLBUTAMIDE (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089111 (pdf not found) INN (TOLBUTAMIDE) TOLBUTAMIDE (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 010670 (pdf not found) INN (TOLBUTAMIDE) ORINASE (PHARMACIA AND UPJOHN) APPROVAL= AP YEAR= 1957 NEWMOLECULARENTITY DISCONTINUED
NDA 012095 (pdf not found) INN (TOLBUTAMIDE SODIUM) ORINASE DIAGNOSTIC (PHARMACIA AND UPJOHN) APPROVAL= AP YEAR= 1961 DISCONTINUED
NDA 012678 (pdf not found) INN (TOLBUTAMIDE) TOLBUTAMIDE (SANDOZ) APPROVAL= AP YEAR= 1974 DISCONTINUED
NDA 086047 (pdf not found) INN (TOLBUTAMIDE) TOLBUTAMIDE (PARKE DAVIS) APPROVAL= AP YEAR= 1979 DISCONTINUED
NDA 086109 (pdf not found) INN (TOLBUTAMIDE) TOLBUTAMIDE (WATSON LABS) APPROVAL= AP YEAR= 1979 DISCONTINUED
NDA 086141 (pdf not found) INN (TOLBUTAMIDE) TOLBUTAMIDE (ALRA) APPROVAL= AP YEAR= 1979 DISCONTINUED
NDA 086445 (pdf not found) INN (TOLBUTAMIDE) TOLBUTAMIDE (NORVIUM BIOSCIENCE) APPROVAL= AP YEAR= 1979 DISCONTINUED
NDA 086574 (pdf not found) INN (TOLBUTAMIDE) TOLBUTAMIDE (CHARTWELL RX) APPROVAL= AP YEAR= 1980 DISCONTINUED
NDA 086926 (pdf not found) INN (TOLBUTAMIDE) TOLBUTAMIDE (DAVA PHARMS INC) APPROVAL= AP YEAR= 1980 DISCONTINUED
NDA 087093 (pdf not found) INN (TOLBUTAMIDE) TOLBUTAMIDE (ANI PHARMS) APPROVAL= AP YEAR= 1980 DISCONTINUED
NDA 087121 (pdf not found) INN (TOLBUTAMIDE) TOLBUTAMIDE (BARR) APPROVAL= AP YEAR= 1981 DISCONTINUED
NDA 087318 (pdf not found) INN (TOLBUTAMIDE) TOLBUTAMIDE (WATSON LABS) APPROVAL= AP YEAR= 1981 DISCONTINUED
NDA 087541 (pdf not found) INN (TOLBUTAMIDE) TOLBUTAMIDE (ASCOT) APPROVAL= AP YEAR= 1983 DISCONTINUED
NDA 088893 (pdf not found) INN (TOLBUTAMIDE) TOLBUTAMIDE (SUPERPHARM) APPROVAL= AP YEAR= 1984 DISCONTINUED
NDA 087876 (pdf not found) INN (TOLBUTAMIDE) TOLBUTAMIDE (VANGARD) APPROVAL= AP YEAR= 1985 DISCONTINUED