e-Drug3D
2
TRIPTORELIN
INN
TRIPTORELIN
cas 57773-63-4
CLASS
ANTINEOPLASTIC
SYNTHETIC ANALOG OF GONADATROPIN RELEASING HORMONE (GNRH)
PALLIATIVE TREATMENT OF ADVANCED PROSTATE CANCER
STIMULATES THE RELEASE OF LUTEINIZING HORMONE
ROUTE (list)
INTRAMUSCULAR
ATC code
L02AE04
PK parameters
VD 31.5 LITER
Cl 12.7 LITER / HOUR
t1/2 3 HOUR
TARGET GONADOTROPIN-RELEASING HORMONE RECEPTOR (GNRH RECEPTOR)
Gonadotropin-releasing hormone receptor UNIPROT P30968 GNRHR
Formula:
C64H82N18O13
Calculated chemical properties:
MW 1312.48
NB_atoms 95
XLogP -3.90
PSA 444.591
NB_HD 21
NB_HA 30
fsp3 0.42
Lipinski(0=no;1=yes) 0
NB_atoms 95
XLogP -3.90
PSA 444.591
NB_HD 21
NB_HA 30
fsp3 0.42
Lipinski(0=no;1=yes) 0
FDA
NDA 020715 (label) INN (TRIPTORELIN PAMOATE) TRELSTAR (VERITY) APPROVAL= AP YEAR= 2000
NDA 021288 (label) INN (TRIPTORELIN PAMOATE) TRELSTAR (VERITY) APPROVAL= AP YEAR= 2001
NDA 022437 (label) INN (TRIPTORELIN PAMOATE) TRELSTAR (VERITY) APPROVAL= AP YEAR= 2010
NDA 208956 (label) INN (TRIPTORELIN PAMOATE) TRIPTODUR KIT (AZURITY) APPROVAL= AP YEAR= 2017
NDA 020715 (label) INN (TRIPTORELIN PAMOATE) TRELSTAR (VERITY) APPROVAL= AP YEAR= 2000
NDA 021288 (label) INN (TRIPTORELIN PAMOATE) TRELSTAR (VERITY) APPROVAL= AP YEAR= 2001
NDA 022437 (label) INN (TRIPTORELIN PAMOATE) TRELSTAR (VERITY) APPROVAL= AP YEAR= 2010
NDA 208956 (label) INN (TRIPTORELIN PAMOATE) TRIPTODUR KIT (AZURITY) APPROVAL= AP YEAR= 2017