e-Drug3D

1995

VILOXAZINE

INN
VILOXAZINE

cas 46817-91-8

CLASS

NERVOUS SYSTEM
SELECTIVE NOREPINEPHRINE REUPTAKE INHIBITOR
TREATMENT OF ADHD

ROUTE (list)

ORAL

ATC code

N06AX09

PK parameters

F 88 PERCENT
Tmax 5 HOUR
PPB 79 PERCENT
t1/2 7.02 HOUR

Solubility

SOLUBLE IN WATER

Target

TARGET NOREPINEPHRINE TRANSPORTER (NET KI=0.63 MICROMOLAR)

Sodium-dependent noradrenaline transporter UNIPROT P23975 SLC6A2

Download SDF file

Morpholine, 2-[(2-ethoxyphenoxy)methyl]-

Formula:
C13H19NO3

Calculated chemical properties:

MW 237.29
NB_atoms 17
XLogP 1.45
PSA 46.292
NB_HD 1
NB_HA 4
fsp3 0.54
Lipinski(0=no;1=yes) 1

FDA
NDA 211964 (pdf not found) INN (VILOXAZINE HYDROCHLORIDE) QELBREE (SUPERNUS PHARMS) APPROVAL= AP YEAR= 2021 NEWMOLECULARENTITY